标题:
多取代吡喃[2,3-c]吡唑类化合物的在离子液体[Bmim]BF4催化下的四组分一锅法合成One-Pot Four-Component Synthesis of Multi-Substituted Pyrano[2,3-c] Pyrazole under Ionic Liquid [Bmim]BF4 Catalysis
作者:
阿地里江•吾买尔江, 李文博, 夏依努尔•艾力, 梁杰
关键字:
多组分反应, 多取代吡喃[2, 3-c]吡唑类化合物, 一锅法合成, 离子液体Multi-Component Reaction, Multi-Substituted Pyrano[2, 3-c]pyrazole, One-Pot Synthesis, Ionic Liquid
期刊名称:
《Journal of Organic Chemistry Research》, Vol.4 No.2, 2016-06-22
摘要:
本文报道了在离子液体[Bmim]BF4催化下以丙酰乙酸甲酯或丙酰乙酸乙酯，苯肼，芳醛和丙二腈等四组分为原料经过一锅法合成了一系列多取代吡喃[2,3-c]吡唑类化合物的方法。该方法具有方便，产率较高等特点，为合成此类化合物提供了一个参考依据。产物的结构通过IR，1H NMR和MS进行表征。
A series of multi-substituted pyrano[2,3-c]pyrazole derivatives were synthesized by one-pot reac-tion of ethyl propionyl acetate, phenylhydrazine, aromatic aldehyde and malononitrile. We developed an efficient and convenient method for the synthesis of multi-substituted pyrano[2,3-c]pyrazoles in high yields using ionic liquid [Bmim]BF4 as a catalyst. And structures of the products were characterized by IR, 1H NMR and MS.