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L. Carretero-Paulet, I. Ahumada, N. Cunillera, et al. Expression and molecular analysis of the Arabidopsis DXR gene encoding 1-deoxy-D-xylulose-5-phosphate reductoisomerase, the first com- mitted enzyme of the 2-C-methyl-D-erythritol-4-phosphate path- way. Plant Physiology, 2002, 129(3): 1581-1591.

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• 标题: 药用植物类异戊二烯代谢途径及其活性产物合成调控研究进展Recent Research on Isoprenoid Biosynthetic Pathway and Metabolic Regulation of Functional Isoprenoids in Medicinal Plants

  作者: 王秋军, 张犇, 王剑文

  关键字: 类异戊二烯化合物, 生物合成, 甲羟戊酸途径, 2C-甲基4-磷酸-4D-赤藓糖醇途径Isoprenoids; Biosynthesis; Mevalonate (MVA) Pathway; -2-C-Methyl-D-Erythritol-4-Phosphate Pathway (MEP)

  期刊名称: 《Botanical Research》, Vol.1 No.2, 2012-07-27

  摘要: 植物类异戊二烯化合物是一类具有多种药理活性的天然产物，其生物合成主要通过甲羟戊酸途径与2C-甲基-4-磷酸-4D-赤藓糖醇途径，对这两条途径的调控研究已成为近年来热点之一。本文就近年来植物类异戊二烯代谢途径的研究进展以及相关活性成分的生物合成调控研究做一综述。 Isoprenoids originally from medicinal plants are natural products of diverse bioactivities. Isopre-noids were synthesized in plants via the mevalonate (MVA) pathway and the 2-C-methyl-D-erythritol-4- phosphate (MEP) pathway whose regulation mechanisms are research hotspots in recent years. This article gives a summary of recent explorations on isoprenoid biosynthetic pathway and metabolic regulation of func-tional isoprenoids in medicinal plants.