标题:
Pd催化苯乙烯脱氢氧化偶联研究Pd(II)-Catalyzed Dehydrogenative Oxidative Coupling of Terminal Alkene of Styrene
作者:
龚颖, 王光祖
关键字:
苯乙烯, 共轭二烯烃, 脱氢Heck反应Styrene, Conjugated Dienes, Dehydrogenative Heck Reaction
期刊名称:
《Journal of Organic Chemistry Research》, Vol.3 No.2, 2015-04-03
摘要:
我们对未活化的苯乙烯末端烯烃进行了脱氢Heck反应的研究，运用Pd(acac)2做催化剂，Cu(OAc)2作氧化剂，并添加少量AgF，乙酸乙酯作溶剂，在100℃下反应24 h，苯乙烯直接脱氢得到1,4-二苯基-1,3-丁二烯，具有共轭结构，能作为许多有价值化合物的中间体，具有潜在的应用价值，我们还对该反应提出了一个可能的机理。
The work about dehydrogenative Heck reaction of unactivated terminal alkene of styrene was studied. Using Pd(acac)2 as catalyst, Cu(OAc)2 as oxidant, EtOAc as solvent, and adding some AgF, at 100˚C for 24 h, styrene was directly dehydrogenized to generate 1,4-dipheny-1,3-butadiene with conjugated construction which can be intermediate of many value compounds, so this reaction has potential value. A plausible mechanism was proposed.