[1]
|
中华医学会骨科学分会关节外科学组, 中国医师协会骨科医师分会骨关节炎学组, 国家老年疾病临床医学研究中心, 等. 中国骨关节炎诊疗指南(2021年版) [J]. 中华骨科杂志, 2021, 41(18): 1291-314.
|
[2]
|
赵彦萍, 林志国, 林书典, 等. 骨关节炎诊疗规范[J]. 中华内科杂志, 2022, 61(10): 1136-1143.
|
[3]
|
中华医学会糖尿病学分会. 中国2型糖尿病防治指南(2020年版) [J]. 中华内分泌代谢杂志, 2021, 37(4): 311-398.
|
[4]
|
Waine, H., Nevinny, D., Rosenthal, J., et al. (1961) Association of Osteoarthritis and Diabetes Mellitus. Tufts Folia Medica, 7, 13-19.
|
[5]
|
Berenbaum, F. (2011) Diabetes-Induced Osteoarthritis: From a New Paradigm to a New Phenotype. Annals of Rheumatic Diseases, 70, 1354-1356. https://doi.org/10.1136/ard.2010.146399
|
[6]
|
Schett, G., Kleyer, A., Per-ricone, C., et al. (2013) Diabetes Is an Independent Predictor for Severe Osteoarthritis: Results from a Longitudinal Co-hort Study. Diabetes Care, 36, 403-409. https://doi.org/10.2337/dc12-0924
|
[7]
|
Rios-Arce, N.D., Hum, N.R. and Loots, G.G. (2022) Interactions between Diabetes Mellitus and Osteoarthritis: From Animal Studies to Clinical Data. JBMR Plus, 6, e10626. https://doi.org/10.1002/jbm4.10626
|
[8]
|
Mobasheri, A., Neama, G., Bell, S., et al. (2002) Human Articular Chondrocytes Express Three Facilitative Glucose Transporter Isoforms: GLUT1, GLUT3 and GLUT9. Cell Biology International, 26, 297-300.
https://doi.org/10.1006/cbir.2001.0850
|
[9]
|
Yutaka, N., Mitsuru, S., Shingo, K., et al. (2022) Reduced Dynamic Loads Due to Hip Dislocation Induce Acetabular Cartilage Degeneration by IL-6 and MMP3 via the STAT3/Periostin/NF-κB Axis. Scientific Reports, 12, Article No. 12207. https://doi.org/10.1038/s41598-022-16585-6
|
[10]
|
毛岩, 杨肖, 孙联文. 晚期糖基化终末产物对骨组织生物力学影响的研究进展[J]. 医用生物力学, 2021, 36(5): 811-817.
|
[11]
|
Li, Q.X., et al. (2021) Hyperglycemia-Induced Accumulation of Advanced Glycosylation End Products in Fibroblast-Like Synoviocytes Promotes Knee Osteoarthritis. Experimental & Molecular Medicine, 53, 1735-1747.
https://doi.org/10.1038/s12276-021-00697-6
|
[12]
|
高希武, 吴疆, 张帅, 等. 膝骨关节炎发生发展与糖尿病的相关性研究[J]. 当代医学, 2021, 27(17): 107-108.
|
[13]
|
Kostopoulou, F., Gkretsi, V., Malizos, K.N., et al. (2012) Central Role of SREBP-2 in the Pathogenesis of Osteoarthritis. PLOS ONE, 7, e35753. https://doi.org/10.1371/journal.pone.0035753
|
[14]
|
Sekar, S., Wu, X., Friis, T., et al. (2018) Saturated Fatty Acids Promote Chondrocyte Matrix Remodeling through Reprogramming of Autophagy Pathways. Nutrition, 54, 144-152. https://doi.org/10.1016/j.nut.2018.02.018
|
[15]
|
Choi, W.-S., Lee, G., Song, W.-H., et al. (2019) The CH25H-CYP7B1-RORα Axis of Cholesterol Metabolism Regulates Osteoarthritis. Nature, 566, 254-258. https://doi.org/10.1038/s41586-019-0920-1
|
[16]
|
Chen, Y., Huang, Y.-C., Yan, C.H., et al. (2017) Abnormal Sub-chondral Bone Remodeling and Its Association with Articular Cartilage Degradation in Knees of Type 2 Diabetes Patients. Bone Research, 5, Article No. 17034.
https://doi.org/10.1038/boneres.2017.34
|
[17]
|
Wang, H.-J., Giambini, H., Chen, J.-W., et al. (2021) Diabetes Mellitus Accelerates the Progression of Osteoarthritis in Streptozotocin-Induced Diabetic Mice by Deteriorating Bone Microarchitecture, Bone Mineral Composition, and Bone Strength of Subchondral Bone. Annals of Translational Medi-cine, 9, 768. https://doi.org/10.21037/atm-20-6797
|
[18]
|
Felson, D.T., Mclaughlin, S., Goggins, J., et al. (2003) Bone Marrow Edema and Its Relation to Progression of Knee Osteoarthritis. Annals of Internal Medicine, 139, 330-336.
https://doi.org/10.7326/0003-4819-139-5_Part_1-200309020-00008
|
[19]
|
金明花, 马佳宁, 胡冰, 等. 膝骨关节炎软骨下骨髓病变磁共振成像与临床表现的相关性分析[J]. 安徽医药, 2022, 26(3): 492-495.
|
[20]
|
Veronese, N., Cooper, C., Reginster, J.-Y., et al. (2019) Type 2 Diabetes Mellitus and Osteoarthritis. Seminars in Arthritis and Rheu-matism, 49, 9-19. https://doi.org/10.1016/j.semarthrit.2019.01.005
|
[21]
|
Scanzello, C.R. and Goldring, S.R. (2012) The Role of Synovitis in Osteoarthritis Pathogenesis. Bone, 51, 249-257.
https://doi.org/10.1016/j.bone.2012.02.012
|
[22]
|
柳椰, 邬波, 马旭, 等. 膝关节骨关节炎患者血清及关节液中Eotaxin-1、MCP-1和VEGF水平变化与临床意义[J]. 大连医科大学学报, 2021, 43(6): 514-519.
|
[23]
|
Gui, T., Lin, Y.K., Huan, S.W., et al. (2019) Elevated Expression of ICAM‐1 in Synovium Is Associated with Early Inflammatory Response for Cartilage Degeneration in Type 2 Diabetes Mellitus. Journal of Cellular Biochemistry, 120, 13177-13186. https://doi.org/10.1002/jcb.28592
|
[24]
|
Childs, B.G., Gluscevic, M., Baker, D.J., et al. (2017) Senescent Cells: An Emerging Target for Diseases of Ageing. Nature Reviews Drug Discovery, 16, 718-735. https://doi.org/10.1038/nrd.2017.116
|
[25]
|
Larrañaga-Vera, A., Lamuedra, A., Pérez-Baos, S., et al. (2017) In-creased Synovial Lipodystrophy Induced by High Fat Diet Aggravates Synovitis in Experimental Osteoarthritis. Arthritis Research & Therapy, 19, Article No. 264.
https://doi.org/10.1186/s13075-017-1473-z
|
[26]
|
De Munter, W., Van Den Bosch, M.H.J., Slöetjes, A.W., et al. (2016) High LDL Levels Lead to Increased Synovial Inflammation and Accelerated Ectopic Bone Formation during Ex-perimental Osteoarthritis. Osteoarthritis and Cartilage, 24, 844-855. https://doi.org/10.1016/j.joca.2015.11.016
|
[27]
|
Muneshige, K., Uchida, K., Kenmoku, T., et al. (2022) Elevation of MMP1 and ADAMTS5 mRNA Expression in Glenohumeral Synovia of Patients with Hypercholesterolemia. Journal of Orthopaedic Surgery and Research, 17, Article No. 97. https://doi.org/10.1186/s13018-022-02998-6
|
[28]
|
Berenbaum, F. and Walker, C. (2020) Osteoarthritis and In-flammation: A Serious Disease with Overlapping Phenotypic Patterns. Postgraduate Medicine, 132, 377-384. https://doi.org/10.1080/00325481.2020.1730669
|
[29]
|
Deeba, F., Younis, S., Qureshi, N., et al. (2021) Effect of Diabetes Mellitus and Anti-Diabetic Drugs on Bone Health—A Review. Journal of Bioresource Management, 8, Article No. 13. https://doi.org/10.35691/JBM.1202.0187
|
[30]
|
李震, 李泽晖, 孙赫, 等. 非编码RNA在骨关节炎中的研究进展[J]. 实用骨科杂志, 2022, 28(12): 1093-1098.
|
[31]
|
Wang, Y.-Z., Liang, S.-K., et al. (2021) LncPVT1 Pro-motes Cartilage Degradation in Diabetic OA Mice by Downregulating miR-146a and Activating TGF-β/SMAD4 Signal-ing. Journal of Bone and Mineral Metabolism, 39, 534-546.
https://doi.org/10.1007/s00774-020-01199-7
|
[32]
|
Kim, D., Song, J., Ahn, C., et al. (2014) Peroxisomal Dysfunc-tion Is Associated with Up-Regulation of Apoptotic Cell Death via miR-223 Induction in Knee Osteoarthritis Patients with Type 2 Diabetes Mellitus. Bone, 64, 124-131.
https://doi.org/10.1016/j.bone.2014.04.001
|
[33]
|
Chuang, T.-Y., Wu, H.-L., Chen, C.-C., et al. (2015) Mi-croRNA-223 Expression Is Upregulated in Insulin Resistant Human Adipose Tissue. Journal of Diabetes Research, 2015, Article ID: 943659. https://doi.org/10.1155/2015/943659
|
[34]
|
袁长深, 官岩兵, 容伟明, 等. 骨关节炎与糖尿病的共同疾病基因及其相关微小RNA的筛选与鉴定[J]. 广西医学, 2022, 44(1): 46-50+57.
|
[35]
|
薛伟, 康少英, 郭洪生, 等. lncRNAs H19在糖尿病骨关节炎软骨下骨中的表达及其意义[J]. 中国医药导报, 2022, 19(20): 25-29.
|
[36]
|
Yan, S.J., et al. (2023) Metformin Regulates Chondrocyte Senescence and Proliferation through mi-croRNA-34a/SIRT1 Pathway in Osteoarthritis. Journal of Orthopaedic Surgery and Research, 18, Article No. 198.
https://doi.org/10.1186/s13018-023-03571-5
|
[37]
|
Ma, P., Gu, B., Xiong, W., et al. (2014) Glimepiride Promotes Osteogenic Differentiation in Rat Osteoblasts via the PI3K/Akt/eNOS Pathway in a High Glucose Microenvironment. PLOS ONE, 9, e112243.
https://doi.org/10.1371/journal.pone.0112243
|
[38]
|
邢亨特, 邱波. 二甲双胍治疗骨关节炎的作用机制研究进展[J]. 现代药物与临床, 2022, 37(9): 2155-2159.
|
[39]
|
Zhang, N., Jiang, H., Bai, Y., et al. (2019) The Molecular Mecha-nism Study of Insulin on Proliferation and Differentiation of Osteoblasts under High Glucose Conditions. Cell Biochem-istry and Function, 37, 385-394.
https://doi.org/10.1002/cbf.3415
|
[40]
|
Meurot, C., Jacques, C., Martin, C., et al. (2022) Targeting the GLP-1/GLP-1R Axis to Treat Osteoarthritis: A New Opportunity? Journal of Orthopaedic Translation, 32, 121-129. https://doi.org/10.1016/j.jot.2022.02.001
|
[41]
|
缪卫红. 2型糖尿病的中医治疗研究进展[J]. 实用老年医学, 2023, 37(2): 116-118+127.
|
[42]
|
张文伟, 邰东旭. 膝骨关节炎中医外治法研究进展[J]. 江西中医药, 2022, 53(6): 70-72.
|
[43]
|
陈倩文, 赵继荣, 陈祁青, 等. 中医药靶向miRNA干预骨关节炎研究进展[J]. 中华中医药学刊, 2022: 1-16.
|
[44]
|
Evans, C.H., Ghivizzani, S.C. and Robbins, P.D. (2023) Osteoarthritis Gene Therapy in 2022. Current Opinion in Rheumatology, 35, 37-43. https://doi.org/10.1097/BOR.0000000000000918
|