[1]
|
Boyton, R.J., Reynolds, C.J., Quigley, K.J. and Altmann, D.M. (2013) Immune Mechanisms and the Impact of the Dis-rupted Lung Microbiome in Chronic Bacterial Lung Infection and Bronchiectasis. Clinical and Experimental Immunology, 171, 117-123. https://doi.org/10.1111/cei.12003
|
[2]
|
孙雪峰, 高金明. 非囊性纤维化性支气管扩张症的免疫调节机制[J]. 国际呼吸杂志, 2014, 34(4): 303-309.
https://doi.org/10.3760/cma.j.issn.1673-436X.2014.04.016
|
[3]
|
Barker, A.F. (2002) Bronchiectasis. The New England Journal of Medicine, 346, 1383-1393.
https://doi.org/10.1056/NEJMra012519
|
[4]
|
Wilson, R., Boyton, R., Laurent, G.J. and Shapiro, S.D. (2006) Bronchiectasis. In: Encyclopedia of Respiratory Medicine, Elsevier, Oxford, UK, 259-268. https://doi.org/10.1016/B0-12-370879-6/00047-8
|
[5]
|
Boyton, R.J. (2009) Regulation of Immunity in Bronchiec-tasis. Medical Mycology, 47, S175-S182.
https://doi.org/10.1080/13693780802163370
|
[6]
|
Martinez-Garcia, M.Á., Oscullo, G. and Garcia-Ortega, A. (2022) Towards a New Definition of Non-Cystic Fibrosis Bronchiectasis. Jornal Brasileiro de Pneumologia, 48, e20220023. https://doi.org/10.36416/1806-3756/e20220023
|
[7]
|
Feng, J., Sun, L., Sun, X., Xu, L., Liu, L., Liu, G., Wang, J., Gao, P., Zhan, S., Chen, Y., Wang, S. and Sun, Y. (2022) Increasing Prevalence and Burden of Bronchiectasis in Urban Chinese Adults, 2013-2017: A Nationwide Population-Based Cohort Study. Respiratory Research, 23, Article No. 111. https://doi.org/10.1186/s12931-022-02023-8
|
[8]
|
Barker, A.F. and Bardana Jr., E.J. (1988) Bronchiecta-sis: Update of an Orphan Disease. American Review of Respiratory Disease, 137, 969-978. https://doi.org/10.1164/ajrccm/137.4.969
|
[9]
|
张艳芳, 冯广满. 大环内酯类药物联合阿米卡星对支气管扩张患者PA形成生物膜的清除作用[J]. 热带医学杂志2017, 17(2): 1593-1596.
|
[10]
|
程克斌, 徐金富, 李惠萍. 支气管扩张症的免疫调节机制及其免疫调节治疗进展[J]. 国际呼吸杂志, 2019, 39(6): 457-461.
|
[11]
|
Cole, P.J. (1986) Inflammation: A Two-Edged Sword—The Model of Bronchiectasis. European Journal of Respiratory Diseases. Sup-plement, 147, 6-15.
|
[12]
|
Chalmers, J.D., Chang, A.B., Chotirmall, S.H., et al. (2018) Bronchiectasis. Nature Reviews Disease Primers, 4, Article No. 45. https://doi.org/10.1038/s41572-018-0042-3
|
[13]
|
Muñoz, G., de Gracia, J., Buxó, M., et al. (2018) Long-Term Benefits of Airway Clearance in Bronchiectasis: A Randomised Placebo-Controlled Trial. European Respiratory Journal, 51, Article ID: 1701926.
https://doi.org/10.1183/13993003.01926-2017
|
[14]
|
Chalmers, J.D., Boersma, W., Lonergan, M., et al. (2019) Long-Term Macrolide Antibiotics for the Treatment of Bronchiectasis in Adults: An Individual Participant Data Me-ta-Analysis. The Lancet Respiratory Medicine, 7, 845-854.
https://doi.org/10.1016/S2213-2600(19)30191-2
|
[15]
|
Haworth, C.S., Bilton, D., Chalmers, J.D., et al. (2019) In-haled Liposomal Ciprofloxacin in Patients with Non-Cystic Fibrosis Bronchiectasis and Chronic Lung Infection with Pseudomonas aeruginosa (ORBIT-3 and ORBIT-4): Two Phase 3, Randomised Controlled Trials. The Lancet Respira-tory Medicine, 7, 213-226.
https://doi.org/10.1016/S2213-2600(18)30427-2
|
[16]
|
Flume, P.A., Chalmers, J.D. and Olivier, K.N. (2018) Ad-vances in Bronchiectasis: Endotyping, Genetics, Microbiome, and Disease Heterogeneity. The Lancet, 392, 880-890. https://doi.org/10.1016/S0140-6736(18)31767-7
|
[17]
|
Xu, J.F., Gao, Y.H., Song, Y.L., Qu, J.M. and Guan, W.J. (2022) Research Advances and Clinical Management of Bronchiectasis: Chinese Perspective. ERJ Open Research, 8, Ar-ticle ID: 00017-2022.
https://doi.org/10.1183/23120541.00017-2022
|
[18]
|
Angrill, J., Agustí, C., De Celis, R., et al. (2002) Bacterial Colonisation in Patients with Bronchiectasis: Microbiological Pattern and Risk Factors. Thorax, 57, 15-19. https://doi.org/10.1136/thorax.57.1.15
|
[19]
|
Watt, A.P., Brown, V., Courtney, J., et al. (2004) Neutrophil Apoptosis, Proinflammatory Mediators and Cell Counts in Bronchiectasis. Thorax, 59, 231-236. https://doi.org/10.1136/thx.2003.008037
|
[20]
|
King, P.T. (2018) The Role of the Immune Response in the Patho-genesis of Bronchiectasis. BioMed Research International, 2018, Article ID: 6802637. https://doi.org/10.1155/2018/6802637
|
[21]
|
Whitters, D. and Stockley, R. (2012) Immunity and Bacterial Colonisa-tion in Bronchiectasis. Thorax, 67, 1006-1013.
https://doi.org/10.1136/thoraxjnl-2011-200206
|
[22]
|
Cowburn, A.S., Condliffe, A.M., Farahi, N., et al. (2008) Ad-vances in Neutrophil Biology: clinical Implications. Chest, 134, 606-612. https://doi.org/10.1378/chest.08-0422
|
[23]
|
Stockley, R.A. (2002) Neutrophils and the Pathogenesis of COPD. Chest, 121, 151S-155S.
https://doi.org/10.1378/chest.121.5_suppl.151S
|
[24]
|
Mikami, M., Llewellyn-Jones, C.G., Bayley, D., et al. (1998) The Chemotactic Activity of Sputum from Patients with Bronchiectasis. American Journal of Respiratory and Critical Care Medicine, 157, 723-728.
https://doi.org/10.1164/ajrccm.157.3.9606120
|
[25]
|
Mitchell, T., Lo, A., Logan, M.R., et al. (2008) Primary Gran-ule Exocytosis in Human Neutrophils Is Regulated by Rac-Dependent Actin Remodelling. American Journal of Physiol-ogy—Cell Physiology, 295, C1354-C1365.
https://doi.org/10.1152/ajpcell.00239.2008
|
[26]
|
Rosenzweig, S.D. (2008) Inflammatory Manifestations in Chronic Granulomatous Disease. Journal of Clinical Immunology, 28, S67-S72. https://doi.org/10.1007/s10875-007-9160-5
|
[27]
|
Reeves, E.P., Lu, H., Jacobs, H.L., et al. (2002) Killing Activity of Neutrophils Is Mediated through Activation of Proteases by Flux. Nature, 416, 291-297. https://doi.org/10.1038/416291a
|
[28]
|
Tung, J.P., Fraser, J.F., Wood, P., et al. (2009) Respiratory Burst Function of Ovine Neurophils. BMC Immunology, 10, Article No. 25. https://doi.org/10.1186/1471-2172-10-25
|
[29]
|
Zheng, L., Shum, I.H., Tipoe, G.L., et al. (2001) Macrophages, Neutrophils and Tumour Necrosis Factor-α Expression in Bronchi-ectatic Airways in Vivo. Respiratory Medicine, 95, 792-798. https://doi.org/10.1053/rmed.2001.1155
|
[30]
|
Stockley, R.A., Hill, S.L., Morrison, H.M. and Starkie, C.M. (1984) Elastolytic Activity of Sputum and Its Relation to Purulence and to Lung Function in Patients with Bronchiectasis. Thorax, 39, 408-413.
https://doi.org/10.1136/thx.39.6.408
|
[31]
|
Shum, D.K.Y., Chan, S.C.H. and Ip, M.S.M. (2000) Neutro-phil-Mediated Degradation of Lung Proteoglycans: Stimulation by Tumor Necrosis Factor-α in Sputum of Patients with Bronchiectasis. American Journal of Respiratory and Critical Care Medicine, 162, 1925-1931. https://doi.org/10.1164/ajrccm.162.5.9907064
|
[32]
|
Paulson, M.L., Freeman, A.F. and Holland, S.M. (2008) Hyper IgE Syndrome: An Update on Clinical Aspects and the Role of Signal Transducer and Activator of Transcription 3. Cur-rent Opinion in Allergy and Clinical Immunology, 8, 527-533. https://doi.org/10.1097/ACI.0b013e3283184210
|
[33]
|
Wood, A.M., Bassford, C., Webster, D., et al. (2011) Vita-min D-Binding Protein Contributes to COPD by Activation of Alveolar Macrophages. Thorax, 66, 205-210. https://doi.org/10.1136/thx.2010.140921
|
[34]
|
Whitwell, F. (1952) A Study of the Pathology and Pathogenesis of Bronchiectasis. Thorax, 7, 213-239.
https://doi.org/10.1136/thx.7.3.213
|
[35]
|
Silva Jones Jr., J.A., Cole, P.J. and Poulter, L.W. (1989) The Immunolog-ical Component of the Cellular Inflammatory Infiltrate in Bronchiectasis. Thorax, 44, 668-673. https://doi.org/10.1136/thx.44.8.668
|
[36]
|
Sepper, R., Konttinen, Y.T., Ingman, T. and Sorsa, T. (1995) Presence, Activities, and Molecular Forms of Cathepsin G, Elastase, α1-Antitrypsin, and α1-Antichymotrypsin in Bronchiectasis. Journal of Clinical Immunology, 15, 27-34.
https://doi.org/10.1007/BF01489487
|
[37]
|
Frija-Masson, J., Martin, C., Regard, L., et al. (2017) Bacteria-Driven Peribronchial Lymphoid Neogenesis in Bronchiectasis and Cystic Fibrosis. European Respiratory Journal, 49, Article ID: 1601873.
https://doi.org/10.1183/13993003.01873-2016
|
[38]
|
Lapa, E., Silva, J.R., Guerreiro, D., Noble, B., et al. (1989) Immunopathology of Experimental Bronchiectasis. The American Journal of Respiratory Cell and Molecular Biology, 1, 297-304. https://doi.org/10.1165/ajrcmb/1.4.297
|
[39]
|
Eller, J., Lapa, E., Silva, J.R., Poulter, L.W., et al. (1994) Cells and Cytokines in Chronic Bronchial Infection. Annals of the New York Academy of Sciences, 725, 331-345. https://doi.org/10.1111/j.1749-6632.1994.tb39816.x
|
[40]
|
Mukae, H., Kadota, J., Kohno, S., et al. (1995) Increase in Activated CD8+ Cells in Bronchoalveolar Lavage Fluid in Patients with Diffuse Panbronchiolitis. American Journal of Respiratory and Critical Care Medicine, 152, 613-618.
https://doi.org/10.1164/ajrccm.152.2.7633715
|
[41]
|
Campbell DA, du Bois RM, Butcher RG, et al. (1986) Density of HLA-DR Antigen Expression on Alveolar Macrophages Is Increased in Pulmonary Sarcoidosis. Clinical and Experi-mental Immunology, 65, 165-171.
|
[42]
|
Saetta, M., Di Stefano, A., Maestrelli, P., et al. (1993) Activated T-Lymphocytes and Macrophages in Bronchial Mucosa of Subjects with Chronic Bronchitis. American Review of Respiratory Disease, 147, 301-306.
https://doi.org/10.1164/ajrccm/147.2.301
|
[43]
|
Bentley, A.M., Menz, G., Storz, C., et al. (1992) Identification of T Lymphocytes, Macrophages and Activated Eosinophils in the Bronchial Mucosa in Intrinsic Asthma. American Review of Respiratory Disease, 146, 500-506.
https://doi.org/10.1164/ajrccm/146.2.500
|
[44]
|
Azzawi, M., Bradley, B., Jeffery, P.K., et al. (1990) Identification of Activated T Lymphocytes and Eosinophils in Bronchial Biopsies in Stable Atopic Asthma. American Review of Respira-tory Disease, 142, 1407-1413.
https://doi.org/10.1164/ajrccm/142.6_Pt_1.1407
|
[45]
|
Poulter, L.W., Russel-Jones, R. and Hobbe, S. (1984) The Significance of Antigen Presenting Cells in Psoriasis. In: Macdonald, D.C., Ed., Immunodermatology, Butterworths, London, 185-188.
https://doi.org/10.1016/B978-0-407-00338-5.50048-X
|
[46]
|
Poulter, L.W., Duke, O., Panayi, G.S., et al. (1985) Activated T Lymphocytes of the Synovial Membrane in Rheumatoid Arthritis and Other Arthropathies. Scandinavian Journal of Immunology, 22, 683-689.
https://doi.org/10.1111/j.1365-3083.1985.tb01931.x
|
[47]
|
Poulter, L.W., Allison, M., Rochardson, A.T., et al. (1987) The Distribution of Lymphocyte Subsets in Inflammatory Bowel Disease and Reactive Synovitis: A Comparison. In: Mielants, H. and Veys, E.M., Eds., Spondyloarthropathies: Involvement of the Gut, Elsevier, Amsterdam, 213-220.
|
[48]
|
Boyton, R.J. and Altmann, D.M. (2016) Bronchiectasis: Current Concepts in Pathogenesis, Immunology, and Microbiology. Annual Review of Pathology: Mechanisms of Disease, 11, 523-554.
https://doi.org/10.1146/annurev-pathol-012615-044344
|
[49]
|
Tan, H.-L., Regamey, N., Brown, S., Bush, A., Lloyd, C.M. and Davies, J.C. (2011) The Th17 Pathway in Cystic Fibrosis Lung Disease. American Journal of Respiratory and Critical Care Medicine, 184, 252-258.
https://doi.org/10.1164/rccm.201102-0236OC
|
[50]
|
Zimmer, J., Andres, E., Donato, L., et al. (2005) Clinical and Immunological Aspects of HLA Class I Deficiency. QJM, 98, 719-727. https://doi.org/10.1093/qjmed/hci112
|
[51]
|
Bard, M., Couderc, L.J., Saimot, A.G., et al. (1998) Accelerated Ob-structive Pulmonary Disease in HIV Infected Patients with Bronchiectasis. European Respiratory Journal, 11, 771-775. https://doi.org/10.1183/09031936.98.11030771
|
[52]
|
Bekir, M., Karakoç Aydıner, E., Yıldızeli, Ş.O., Öğülür, İ., Kocakaya, D., Barış, S., Eryüksel, E., Özen, A. and Ceyhan, B.B. (2021) Primary Immun Deficiency in Patients with Non-Cystic Fibrosis Bronchiectasis and Its Relationship with Clinical Parameters. Turkish Thoracic Journal, 22, 37-44. https://doi.org/10.5152/TurkThoracJ.2020.19077
|
[53]
|
Gaga, M., Bentley, A.M., Humbert, M., et al. (1998) In-creases in CD4+ T Lymphocytes, Macrophages, Neutrophils and Interleukin 8 Positive Cells in the Airways of Patients with Bronchiectasis. Thorax, 53, 685-691.
https://doi.org/10.1136/thx.53.8.685
|
[54]
|
Ip, M., Lauder, I.J., Wong, W.Y., et al. (1993) Multivariate Analysis of Factors Affecting Pulmonary Function in Bronchiectasis. Respiration, 60, 45-50. https://doi.org/10.1159/000196172
|
[55]
|
De Gracia, J., Rodrigo, M.J., Morell, F., et al. (1996) IgG Subclass Defi-ciencies Associated with Bronchiectasis. American Journal of Respiratory and Critical Care Medicine, 153, 650-655. https://doi.org/10.1164/ajrccm.153.2.8564113
|
[56]
|
Hill, S.L., Mitchell, J.L., Burnett, D. and Stockley, R.A. (1998) IgG Subclasses in the Serum and Sputum from Patients with Bronchiectasis. Thorax, 53, 463-468. https://doi.org/10.1136/thx.53.6.463
|
[57]
|
Ooi, G.C., Khong, P.L., Chan-Yeung, M., et al. (2002) High-Resolution CT Quantification of Bronchiectasis: Clinical and Functional Correlation. Radiology, 225, 663-672. https://doi.org/10.1148/radiol.2253011575
|
[58]
|
Pasteur, M.C., Helliwell, S.M., Houghton, S.J., et al. (2000) An Investigation into Causative Factors in Patients with Bronchiectasis. American Journal of Respiratory and Critical Care Medicine, 162, 1277-1284.
https://doi.org/10.1164/ajrccm.162.4.9906120
|
[59]
|
King, P.T., Hutchinson, P., Holmes, P.W., et al. (2006) As-sessing Immune Function in Adult Bronchiectasis. Clinical & Experimental Immunology, 144, 440-446. https://doi.org/10.1111/j.1365-2249.2006.03091.x
|
[60]
|
Vendrell, M., de Gracia, J., Rodrigo, M.-J., et al. (2005) Antibody Production Deficiency with Normal IgG Levels in Bronchiectasis of Unknown Etiology. Chest, 127, 197-204. https://doi.org/10.1378/chest.127.1.197
|
[61]
|
Pilette, C., Detry, B., Guisset, A., et al. (2006) Dual Effect of Neutro-phils on Secretory Component Production by Human Bronchial Epithelial Cells. European Respiratory Review, 15, 175-176.
https://doi.org/10.1183/09059180.00010111
|
[62]
|
Burnett, D., Crocker, J. and Stockley, R.A. (1987) Cells contain-Ing IgA Subclasses in Bronchi of Subjects with and without Chronic Obstructive Pulmonary Disease. Journal of Clinical Pathology, 40, 1217-1220.
https://doi.org/10.1136/jcp.40.10.1217
|
[63]
|
Burnett, D., Hill, S.L. and Bradwell, A.R. (1990) IgA Subclasses in Sputum from Patients with Bronchiectasis. Respiratory Medicine, 84, 123-127. https://doi.org/10.1016/S0954-6111(08)80014-5
|
[64]
|
Skaaby, T., Husemoen, L.L., Thuesen, B.H., et al. (2017) IgE Sensitization to Inhalant Allergens and the Risk of Airway Infection and Disease: A Population-Based Study. PLOS ONE, 12, e0171525.
https://doi.org/10.1371/journal.pone.0171525
|
[65]
|
Chalmers, J.D., McHugh, B.J., Doherty, C., et al. (2013) Man-nose-Binding Lectin Deficiency and Disease Severity in Non-Cystic Fibrosis Bronchiectasis: A Prospective Study. The Lancet Respiratory Medicine, 1, 224-232.
https://doi.org/10.1016/S2213-2600(13)70001-8
|
[66]
|
Rogan, M.P., Geraghty, P., Green, C.M., et al. (2006) Anti-microbial Proteins and Polypeptides in Pulmonary Innate Defence. Respiratory Research, 7, Article No. 29. https://doi.org/10.1186/1465-9921-7-29
|
[67]
|
Guan, W.J., Gao, Y.H., Xu, G., et al. (2015) Sputum Bacteriology in Steady-State Bronchiectasis in Guangzhou, China. The International Journal of Tuberculosis and Lung Disease, 19, 610-619. https://doi.org/10.5588/ijtld.14.0613
|
[68]
|
Asad, S. and Opal, S. (2008) Bench-to-Bedside Review: Quorum Sensing and the Role of Cell-to-Cell Communication during Invasive Bacterial Infection. Critical Care, 12, Ar-ticle No. 236. https://doi.org/10.1186/cc7101
|
[69]
|
Telford, G., Wheeler, D. and Williams, P. (1998) The Pseudo-monas aeruginosa Quorum-Sensing Signal Molecule N- (3-oxododecanoyl)-L-homoserine Lactone Has Immunomodu-latory Activity. Infection and Immunity, 66, 36-42.
https://doi.org/10.1128/IAI.66.1.36-42.1998
|
[70]
|
Ritchie, A.J., Jansson, A., Stallberg, J., et al. (2005) The Pseu-domonas aeruginosa Quorum-Sensing Signal Molecule N-(3-oxododecanoyl)-L-homoserine Lactone Inhibits T-Cell Differentiation and Cytokine Production by a Mechanism Involving an Early Step in T-Cell Activation. Infection and Immunity, 73, 1648-1655.
https://doi.org/10.1128/IAI.73.3.1648-1655.2005
|
[71]
|
Smith, R.S., Harris, S.G., Phipps, R., et al. (2002) The Pseudomonas aeruginosa Quorum-Sensing Molecule N-(3- Oxododecanoyl)Homoserine Lactone Contributes to Viru-lence and Induces Inflammation in Vivo. Journal of Bacteriology, 184, 1132-1139. https://doi.org/10.1128/jb.184.4.1132-1139.2002
|
[72]
|
Wang, H., Ji, X.B., Mao, B., et al. (2018) Pseudomonas aeruginosa Isolation in Patients with Non-Cystic Fibrosis Bronchiectasis: A Retrospective Study. BMJ Open, 8, e014613. https://doi.org/10.1136/bmjopen-2016-014613
|
[73]
|
Luo, R.G., Miao, X.Y., Luo, L.L., et al. (2019) Presence of pldA and exoU in Mucoid Pseudomonas aeruginosa Is Associated with High Risk of Exacerbations in Non-Cystic Fi-brosis Bronchiectasis Patients. Clinical Microbiology and Infection, 25, 601-606. https://doi.org/10.1016/j.cmi.2018.07.008
|
[74]
|
Finch, S., McDonnell, M.J., Abo-Leyah, H., et al. (2015) A Com-prehensive Analysis of the Impact of Pseudomonas aeruginosa Colonization on Prognosis in Adult Bronchiectasis. An-nals of the American Thoracic Society, 12, 1602- 1611. https://doi.org/10.1513/AnnalsATS.201506-333OC
|
[75]
|
Clementi, C.F. and Murphy, T.F. (2011) Non-Typeable Haemophilus influenzae Invasion and Persistence in the Human Respiratory Tract. Frontiers in Cellular and Infection Microbiology, 1, Article 1.
https://doi.org/10.3389/fcimb.2011.00001
|
[76]
|
King, P.T., Hutchinson, P.E., Johnson, P.D., Holmes, P.W., Freez-er, N.J. and Holdsworth, S.R. (2003) Adaptive Immunity to Nontypeable Haemophilus influenzae. American Journal of Respiratory and Critical Care Medicine, 167, 587-592. https://doi.org/10.1164/rccm.200207-728OC
|
[77]
|
Wynn, T.A. (2004) Fibrotic Disease and the TH1/TH2 Paradigm. Nature Reviews Immunology, 4, 538-594.
https://doi.org/10.1038/nri1412
|
[78]
|
Pasteur, M.C., Bilton, D. and Hill, A.T. (2010) British Thoracic Society Guideline for Non-CF Bronchiectasis. Thorax, 65, 577. https://doi.org/10.1136/thx.2010.142778
|
[79]
|
Chang, A.B., Bell, S.C., Torzillo, P.J., et al. (2015) Chronic Suppurative Lung Disease and Bronchiectasis in Children and Adults in Australia and New Zealand Thoracic Society of Australia and New Zealand guidelines. Medical Journal of Australia, 202, 130. https://doi.org/10.5694/mjac14.00287
|
[80]
|
Polverino, E., Goeminne, P.C., McDonnell, M.J., et al. (2017) European Respiratory Society Guidelines for the Management of Adult Bronchiectasis. European Respiratory Journal, 50, Article ID: 1700629.
https://doi.org/10.1183/13993003.00629-2017
|
[81]
|
Hill, A.T., Sullivan, A.L., Chalmers, J.D., et al. (2019) British Thoracic Society Guideline for Bronchiectasis in Adults. Thorax, 74, 1-69. https://doi.org/10.1136/thoraxjnl-2018-212463
|
[82]
|
Bronchiectasis Expert Consensus Writing Group, Pulmonary Infection Assembly, Chinese Thoracic Society (2021) [Expert Consensus on the Diagnosis and Treatment of Adult Bronchiectasis in China]. Chinese Journal of Tuberculosis and Respiratory Diseases, 44, 311-321.
|
[83]
|
Wong, C., Jayaram, L., Karalus, N., et al. (2012) Azithromycin for Prevention of Exacerbations in Non-Cystic Fibrosis Bronchiec-tasis (EMBRACE): A Randomised, Double-Blind, Placebo-Controlled Trial. The Lancet, 380, 660-667.
https://doi.org/10.1016/S0140-6736(12)60953-2
|
[84]
|
Serisier, D.J., Martin, M.L., McGuckin, M.A., et al. (2013) Effect of Long-Term, Low-Dose Erythromycin on Pulmonary Exacerbations among Patients with Non-Cystic Fibrosis Bronchiectasis: The BLESS Randomized Controlled Trial. Journal of the American Medical Association, 309, 1260-1267. https://doi.org/10.1001/jama.2013.2290
|
[85]
|
Altenburg, J., de Graaff, C.S., Stienstra, Y., et al. (2013) Effect of Azithromycin Maintenance Treatment on Infectious Exacerbations among Patients with Non-Cystic Fibrosis Bronchiec-tasis: The BAT Randomized Controlled Trial. The Journal of the American Medical Association, 309, 1251-1259. https://doi.org/10.1001/jama.2013.1937
|
[86]
|
Fan, L.C., Lin, J.L., Yang, J.W., et al. (2017) Macrolides Protect against Pseudomonas aeruginosa Infection via Inhibition of Inflammasomes. American Journal of Physiology-Lung Cellular and Molecular Physiology, 313, L677-L686.
https://doi.org/10.1152/ajplung.00123.2017
|
[87]
|
Hodge, S., Tran, H.B., Hamon, R., et al. (2017) Nonantibiotic Macrolides Restore Airway Macrophage Phagocytic Function with Potential Anti-Inflammatory Effects in Chronic Lung Diseases. American Journal of Physiology-Lung Cellular and Molecular Physiology, 312, L678-L687. https://doi.org/10.1152/ajplung.00518.2016
|
[88]
|
Stevens, T., Ekholm, K., Granse, M., et al. (2011) AZD9668: Pharmacological Characterization of a Novel Oral Inhibitor of Neutrophil Elastase. Journal of Pharmacology and Ex-perimental Therapeutics, 339, 313-320.
https://doi.org/10.1124/jpet.111.182139
|
[89]
|
King, P.T., Sharma, R., O’Sullivan, K.M., et al. (2017) Deoxyribonu-clease 1 Reduces Pathogenic Effects of Cigarette Smoke Exposure in the Lung. Scientific Reports, 7, Article No. 12128. https://doi.org/10.1038/s41598-017-12474-5
|
[90]
|
Brinkmann, V. and Zychlinsky, A. (2012) Neutrophil Extracel-lular Traps: Is Immunity the Second Function of Chromatin? The Journal of Cell Biology, 198, 773-783. https://doi.org/10.1083/jcb.201203170
|
[91]
|
Chen, Z.G., Li, Y.Y., Wang, Z.N., et al. (2018) Aberrant Epithelial Remodeling with Impairment of Cilia Architecture in Non-Cystic Fibrosis Bronchiectasis. Journal of Thoracic Disease, 10, 1753-1764.
https://doi.org/10.21037/jtd.2018.02.13
|
[92]
|
Tamaoki, J., Chiyotani, A., Kobayashi, K., et al. (1992) Effect of In-domethacin on Bronchorrhea in Patients with Chronic Bronchitis, Diffuse Panbronchiolitis or Bronchiectasis. American Review of Respiratory Disease, 145, 548-552.
https://doi.org/10.1164/ajrccm/145.3.548
|
[93]
|
Elborn, J.S., Johnstone, B., Allen, F., et al. (1992) Inhaled Steroids in Patients with Bronchiectasis. Respiratory Medicine, 86, 121-124. https://doi.org/10.1016/S0954-6111(06)80227-1
|
[94]
|
Rayner, C.F., Rutman, A., Dewar, A., et al. (1995) Ciliary Disorientation in Patients with Chronic Upper Respiratory Tract Inflammation. American Journal of Respiratory and Critical Care Medicine, 151, 800-804.
https://doi.org/10.1164/ajrccm/151.3_Pt_1.800
|
[95]
|
Tarzi, M.D., Grigoriadou, S., Carr, S.B., Kuitert, L.M. and Longhurst, H.J. (2009) Clinical Immunology Review Series: An Approach to the Management of Pulmonary Disease in Primary Antibody Deficiency. Clinical & Experimental Immunology, 155, 147-155. https://doi.org/10.1111/j.1365-2249.2008.03851.x
|
[96]
|
Chapel, H.M. (1994) Fortnightly Review: Concensus on Diagnosis and Management of Primary Antibody Deficiencies. BMJ, 308, Article No. 581. https://doi.org/10.1136/bmj.308.6928.581
|
[97]
|
Stubbs, A., Bangs, C., Shillitoe, B., et al. (2018) Bronchiectasis and Deteriorating Lung Function in Agammaglobulinaemia Despite Immunoglobulin Replacement Therapy. Clinical & Ex-perimental Immunology, 191, 212-219.
https://doi.org/10.1111/cei.13068
|
[98]
|
Sumitani, M., Tochino, Y., Kamimori, T., et al. (2008) Additive Inoculation of Influenza Vaccine and 23-Valent Pneumococcal Polysaccharide Vaccine to Prevent Lower Respiratory Tract Infections in Chronic Respiratory Disease Patients. Internal Medicine, 47, 1189-1197. https://doi.org/10.2169/internalmedicine.47.0799
|
[99]
|
成人支气管扩张症诊治专家共识编写组. 成人支气管扩张症诊治专家共识[J]. 中华结核和呼吸杂志, 2012, 35(7):485-492. https://doi.org/10.3760/cma.j.issn.1001-0939.2012.07.003
|
[100]
|
Al-Jahdali, H., Alshimemeri, A., Mobeireek, A., et al. (2017) The Saudi Thoracic Society Guidelines for Diagnosis and Management of Noncystic Fibrosis Bronchiectasis. The Annals of Thoracic Surgery, 12, 135-161.
https://doi.org/10.4103/atm.ATM_171_17
|