[1]
|
Dominissini, D., Moshitch-Moshkovitz, S., Schwartz, S., et al. (2012) Topology of the Human and Mouse m6A RNA Methylomes Revealed by m6A-seq. Nature, 485, 201-206. https://doi.org/10.1038/nature11112
|
[2]
|
Wang, X., Zhao, B.S., Roundtree, I.A., et al. (2015) N6-Methyladenosine Modulates Messenger RNA Translationefficiency. Cell, 161, 1388-1399. https://doi.org/10.1016/j.cell.2015.05.014
|
[3]
|
Wu, Y., Yang, X., Chen, Z., et al. (2019) m6A-Induced lncRNA RP11 Triggers the Dissemination of Colorectal Cancer Cells via Upregulation of Zeb1. Molecular Cancer, 18, Article No. 87. https://doi.org/10.1186/s12943-019-1014-2
|
[4]
|
Han, J., Wang, J.Z., Yang, X., et al. (2019) METTL3 Promote Tumor Proliferation of Bladder Cancer by Accelerating Pri-miR221/222 Maturation in m6A-Dependent Manner. Molecular Cancer, 18, 110.
https://doi.org/10.1186/s12943-019-1036-9
|
[5]
|
Zhu, W., Si, Y., Xu, J., et al. (2020) Methyl-Transferase like 3 Promotes Colorectal Cancer Proliferation by Stabilizing CCNE1 mRNA in an m6A-Dependent Manner. Cellular and Molecular Medicine, 24, 3521-3533.
https://doi.org/10.1111/jcmm.15042
|
[6]
|
Zhao, X., Yang, Y., Sun, B.F., et al. (2014) FTO-Dependent Demethyla-tion of N6-Methyladenosine Regulates mRNA Splicing and Is Required for Adipogenesis. Cell Research, 24, 1403-1419. https://doi.org/10.1038/cr.2014.151
|
[7]
|
Luo, G.Z., MacQueen, A., Zheng, G., et al. (2014) Unique Features of the m6A Methylome in Arabidopsis Thaliana. Nature Communications, 5, Article No. 5630. https://doi.org/10.1038/ncomms6630
|
[8]
|
Zhu, W., Wang, J.Z., Xu, Z., et al. (2019) Detection of N6methyladenosine Modification Residues (Review). International Journal of Molecular Medicine, 43, 2267-2278. https://doi.org/10.3892/ijmm.2019.4169
|
[9]
|
Ping, X.L., Sun, B.F., Wang, L., et al. (2014) Mammalian WTAP Is a Regulatory Subunit of the RNA N6-Methyla- denosine Methyltransferase. Cell Research, 24, 177-189. https://doi.org/10.1038/cr.2014.3
|
[10]
|
Zhu, W., Wang, J.Z., Wei, J.F., et al. (2021) Role of m6A Methyltransferase Component VIRMA in Multiple Human cancers (Review). Cancer Cell International, 7, Article No. 172. https://doi.org/10.1186/s12935-021-01868-1
|
[11]
|
Qian, J.Y., Gao, J., Sun, X., et al. (2019) KIAA1429 acts as an Oncogenic Factor in Breast Cancer by Regulating CDK1 in an N6-Methyladenosine-Independent Manner. Oncogene, 38, 6123-6141.
https://doi.org/10.1038/s41388-019-0861-z
|
[12]
|
Pendleton, K.E., Chen, B., Liu, K., et al. (2017) The U6 snRNA m6A Methyltransferase METTL16 Regulates SAM Synthetase Intron Retention. Cell, 169, 824-835.E14. https://doi.org/10.1016/j.cell.2017.05.003
|
[13]
|
Knuckles, P., Lence, T., Haussmann, I.U., et al. (2018) Zc3h13/Flacc Is Required for Adenosine Methylation by Bridging the mRNA-Binding Factor Rbm15/ Spenito to the m6A Machinery Component Wtap/Fl(2)d. Genes & Development, 32, 415-429. https://doi.org/10.1101/gad.309146.117
|
[14]
|
Deng, X., Su, R., Weng, H., et al. (2018) RNA N6-Methyladenosine Modification in Cancers: Current Status and Perspectives. Cell Research, 28, 507-517. https://doi.org/10.1038/s41422-018-0034-6
|
[15]
|
Ruzicka, K., Zhang, M., Campilho, A., et al. (2017) Identification of Factors Required for m6 A mRNA Methylation in Arabidopsis Reveals a Role for the Conserved E3 Ubiquitin Ligase HAKAI. New Phytologist, 215, 157-172.
https://doi.org/10.1111/nph.14586
|
[16]
|
Chen, T., Hao, Y.J., Zhang, Y., et al. (2015) m6A RNA Methylation Is Regulated by MicroRNAs and Promotes Reprogramming to Pluripotency. Cell Stem Cell, 16, 289-301. https://doi.org/10.1016/j.stem.2015.01.016
|
[17]
|
Geula, S., Moshitch-Moshkovitz, S., Dominissini, D., et al. (2015) Stem Cells. m6A mRNA Methylation facilitates Resolution of Naive Pluripotency toward Differentiation. Science, 347, 1002-1006.
https://doi.org/10.1126/science.1261417
|
[18]
|
Fustin, J.M., Kojima, R., Itoh, K., et al. (2018) Two Ck1delta Tran-scripts Regulated by m6A Methylation Code for Two Antagonistic Kinases in the Control of the Circadian Clock. Cell Bi-ology, 115, 5980-5985.
https://doi.org/10.1073/pnas.1721371115
|
[19]
|
Lan, T., Li, H., Zhang, D., Xu, L., et al. (2019) KIAA1429 Contrib-utes to Liver Cancer Progression through N6-me- thyl-0denosine-Dependent Post-Transcriptional Modification of GATA3. Molecular Cancer, 18, Article No. 186.
https://doi.org/10.1186/s12943-019-1106-z
|
[20]
|
Miao, R., Dai, C.C., Mei, L., et al. (2020) KIAA1429 Regulates Cell Proliferation by Targeting C-Jun Messenger RNA-Directly in Gastric Cancer. Journal of Cellular Physiology, 235, 7420-7432. https://doi.org/10.1002/jcp.29645
|
[21]
|
Yang, D.S., Chang, S., Li, F.C., et al. (2021) m6A Transferase KIAA1429-Stabilized LINC00958 Accelerates Gastric Cancer Aerobic Glycolysis through Targeting GLUT1. IUBMB Life, 73, 1325-1333. https://doi.org/10.1002/iub.2545
|
[22]
|
Paramasivam, A., George, R. and Vijayashree Pri-yadharsini, J. (2021) Aberrations of m6A Regulators Are Associated with Tumorigenesis and Metastasis in Head and Neck Squamous Cell Carcinoma. Archives of Oral Biology, 122, Article ID: 105030. https://doi.org/10.1016/j.archoralbio.2020.105030
|
[23]
|
Lobo, J., Costa, A.L., Cantante, M., et al. (2019) m6A RNA Modification and Its Writer/Reader VIRMA/YTHDF3 in Testicular Germ Cell Tumors: A Role in Seminoma Phenotype Maintenance. Journal of Translational Medicine, 17, Article No. 79. https://doi.org/10.1186/s12967-019-1837-z
|
[24]
|
Horiuchi, K., Kawamura, T., Iwanari, H., et al. (2013) Identifica-tion of Wilms’ Tumor 1-Associating Protein Complex and Its Role in Alternative Splicing and the Cell Cycle. Biological Chemistry, 288, 33292-33302.
https://doi.org/10.1074/jbc.M113.500397
|
[25]
|
Wen, J., Lv, R., Ma, H., et al. (2018) Zc3h13 Regulates Nuclear RNA m6A Methylation and Mouse Embryonic Stem Cell Self-Renewal. Molecular Cancer, 69, 1028-1038.E6. https://doi.org/10.1016/j.molcel.2018.02.015
|
[26]
|
Yue, Y., Liu, J., Cui, X., et al. (2018) VIRMA Mediates Prefer-ential m6A mRNA Methylation in 3’UTR and near Stop Codon and Associates with Alternative Polyadenylation. Cell Discovery, 4, Article No. 10.
https://doi.org/10.1038/s41421-018-0019-0
|
[27]
|
Li, Y.K., Xiao, J., Bai, J., et al. (2019) Molecular Characterization and Clinical Relevance of m6A Regulators across 33 Cancer Types. Molecular Cancer, 18, Article No. 137. https://doi.org/10.1186/s12943-019-1066-3
|
[28]
|
XU, D., SHAO, J., SONG, H., et al. (2020) The YTH Domain Family of N6-Methyladenosine“Readers”in the Diagnosis and Prognosis of Colonic Adenocarcinoma. BioMed Research International, 2020, Article ID: 9502560.
https://doi.org/10.1155/2020/9502560
|
[29]
|
Liu, L., Liu, X., Dong, Z., et al. (2019) N6-Methyladenosine-Related Genomic Targets Are Altered in Breast Cancer Tissue and Associated with Poor Survival. Cancer, 10, 5447-5459. https://doi.org/10.7150/jca.35053
|
[30]
|
Cheng, X., Li, M., Rao, X., et al. (2019) KIAA1429 Regulates the Migra-tion and Invasion of Hepatocellular Carcinoma by Altering m6A Modification of ID2 mRNA. OncoTargets and Thera-py, 12, 3421-3428.
https://doi.org/10.2147/OTT.S180954
|
[31]
|
Wang, Y.Z., Ren, F., Song, Z.X., et al. (2020) Multiomics Profile and Prognostic Gene Signature of m6A Regulators in Uterine Corpus Endometrial Carcinoma. Journal of Cancer, 11, 6390-6401. https://doi.org/10.7150/jca.46386
|
[32]
|
Li, F.W., Wang, H., Huang, H.R., et al. (2020) m6A RNA Methylation Regulators Participate in the Malignant Progression and Have Clinical Prognostic Value in Lung Adenocar-cinoma. Frontiers in Genetics, 11, Article No. 994.
https://doi.org/10.3389/fgene.2020.00994
|
[33]
|
Zhao, H.Y., Xu, Y., Xie, Y.L., et al. (2021) m6A Regulators Is Differently Expressed and Correlated with Immune Response of Esophageal Cancer. Frontiers in Cell and Developmen-tal Biology, 9, Article ID: 650023.
https://doi.org/10.3389/fcell.2021.650023
|
[34]
|
Lobo, J., Barros-Silva, D., Henrique, R., et al. (2018) The Emerging role of Epitranscriptomics in Cancer: Focus on Urological Tumors. Genes, 9, Article No. 552. https://doi.org/10.3390/genes9110552
|
[35]
|
Fan, L., Lin, Y., Lei, H., et al. (2020) A Newly Defined Risk Signature, Consisting of Three m6A RNA Methylation Regulators, Predicts the Prognosis of Ovarian Cancer. Aging, 12, 18453-18475. https://doi.org/10.18632/aging.103811
|
[36]
|
Hou, J., Shan, H., Zhang, Y., et al. (2020) m6A RNA Methylation Regulators Have Prognostic Value in Papillary Thyroid Carcinoma. American Journal of Otolaryngology, 41, Article ID: 102547.
https://doi.org/10.1016/j.amjoto.2020.102547
|
[37]
|
Qu, N., Qin, S., Zhang, X., et al. (2020) Multiple m6 A RNA Methylation Modulators Promote the Malignant Progression of Hepatocellular Carcinoma and Affect Its Clinical Progno-sis. BMC Cancer, 20, Article No. 165.
https://doi.org/10.1186/s12885-020-6638-5
|
[38]
|
Wang, M., Yang, Y., Yang, J., et al. (2020) Circ_KIAA1429 Accelerates Hepatocellular Carcinoma Advancement through the Mechanism of m6 A-YTHDF3-Zeb1. Life Sciences, 257, Article ID: 118082.
https://doi.org/10.1016/j.lfs.2020.118082
|
[39]
|
Chen, M., Nie, Z.Y., Wen, X.H., et al. (2019) m6A RNA Methyla-tion Regulators Can Contribute to Malignant Progression and Impact the Prognosis of Bladder Cancer. Bioscience Re-ports, 39, Article ID: BSR20192892.
https://doi.org/10.1042/BSR20192892
|
[40]
|
Sun, Z., Jing, C., Xiao, C., et al. (2020) Prognostic Risk Signature Based on the Expression of Three m6A RNA Methylation Regulatory Genes in Kidney Renal Papillary Cell Carcinoma. Aging, 12, 22078-22094.
https://doi.org/10.18632/aging.104053
|
[41]
|
Tsunedomi, R., Iizuka, N., Tamesa, T., et al. (2008) Decreased ID2 Promotes Metastatic Potentials of Hepatocellular Carcinoma by Altering Secretion of Vascular Endothelial Growth Fac-tor. Clinical Cancer Research, 14, 1025-1031.
https://doi.org/10.1158/1078-0432.CCR-07-1116
|
[42]
|
Lasorella, A., Benezra, R. and Iavarone, A. (2014) The ID Proteins: Master Regulators of Cancer Stem Cells and Tumour Aggressiveness. Nature Reviews Cancer, 14, 77-91. https://doi.org/10.1038/nrc3638
|
[43]
|
Havrda, M.C., Paolella, B.R., Ran, C., et al. (2014) Id2 Mediates Oligoden-drocyte Precursor Cell Maturation Arrest and Is Tumorigenic in a PDGF-Rich Microenvironment. Cancer Research, 74, 1822-1832.
https://doi.org/10.1158/0008-5472.CAN-13-1839
|
[44]
|
Jacob, R., Zander, S. and Gutschner, T. (2018) The Dark Side of the Epitranscriptome: Chemical Modifications in Long Non-Coding RNAs. International Journal of Molecular Sciences, 18, Article No. 2387.
https://doi.org/10.3390/ijms18112387
|
[45]
|
Barros-Silva D, Lobo, J., Guimarães-Teixeira, C., et al. (2020) VIRMA-Dependent N6-Methyladenosine Modifications Regulate the Expression of Long Non-Coding RNAs CCAT1 and CCAT2 in Prostate Cancer. Cancers, 12, Article No. 771. https://doi.org/10.3390/cancers12040771
|
[46]
|
Barros-Silva, D. and Costa-Pinheiro, P. (2018) Duarte HMi-croRNA-27a-5p Regulation by Promoter Methylation and MYC Signaling in Prostate Carcinogenesis. Cell Death & Disease, 9, Article No. 167.
https://doi.org/10.1038/s41419-017-0241-y
|
[47]
|
Hamilton, M.J., Young, M.D., Sauer, S., et al. (2015) The Inter-play of Long Non-Coding RNAs and MYC in Cancer. Aims Biophysics, 2, 794-809. https://doi.org/10.3934/biophy.2015.4.794
|
[48]
|
Zhuang, K., Wu, Q., Jiang, S., et al. (2016) CCAT1 Promotes Laryngeal Squamous Cell Carcinoma Cell Proliferation and Invasion. American Journal of Translational Research, 8, 4338-4345.
|
[49]
|
Yu, Y., Nangia-Makker, P., Farhana, L., et al. (2017) A Novel Mechanism of lncRNA and miRNA Interaction: CCAT2 Regulates miR-145 Expression by Suppressing Its Maturation Process in Colon Cancer Cells. Mo-lecular Cancer, 16, Article No. 155. https://doi.org/10.1186/s12943-017-0725-5
|