[1]
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Keck, C.M. and Müller, R.H. (2006) Drug Nanocrystals of Poorly Soluble Drugs Produced by High Pressure Homogenisation. European Journal of Pharmaceutics & Biopharmaceutics, 62, 3-16.
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[2]
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Möschwitzer, J., Achleitner, G., Pomper, H., et al. (2004) Development of an Intravenously Injectable Chemically Stable Aqueous Omeprazole Formulation Using Nanosuspension Technology. European Journal of Pharmaceutics & Biopharmaceutics, 58, 615-619.
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[3]
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Yang, H., Teng, F., Wang, P., et al. (2014) Investigation of a Nanosuspension Stabilized by Soluplus® to Improve Bioavailability. International Journal of Pharmaceutics, 477, 88-95.
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[4]
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Ahuja, M., Dhake, A.S., Sharma, S.K., et al. (2011) Diclofenac-Loaded Eudragit S100 Nanosuspension for Ophthalmic Delivery. Journal of Microencapsulation, 28, 37-45. https://doi.org/10.3109/02652048.2010.523794
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[5]
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Jacobs, C. and Müller, R.H. (2002) Production and Characterization of a Budesonide Nanosuspension for Pulmonary Administration. Pharmaceutical Research, 19, 189-194. https://doi.org/10.1023/A:1014276917363
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[6]
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Zakir, F., Sharma, H., Kaur, K., et al. (2011) Nanocrystallization of Poorly Water Soluble Drugs for Parenteral Administration. Journal of Biomedical Nanotechnology, 7, 127-129. https://doi.org/10.1166/jbn.2011.1234
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[7]
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Raula, J., Rahikkala, A., Halkola, T., et al. (2013) Coated Particle Assemblies for the Concomitant Pulmonary Administration of Budesonide and Salbutamol Sulphate. International Journal of Pharmaceutics, 441, 248-254.
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[8]
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Du, J., Zhou, Y., Wang, L., et al. (2016) Effect of PEGylated Chitosan as Multifunctional Stabilizer for Deacetyl Mycoepoxydience Nanosuspension Design and Stability Evaluation. Carbohydrate Polymers, 153, 471-481.
|
[9]
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Sharma, P., Zujovic, Z.D., Bowmaker, G.A., et al. (2011) Evaluation of a Crystalline Nanosuspension: Polymorphism, Process Induced Transformation and in Vivo Studies. International Journal of Pharmaceutics, 408, 138-151.
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[10]
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Hasegawa, Y., Higashi, K., Yamamoto, K., et al. (2015) Direct Evaluation of Molecular States of Piroxicam/Polox- amer Nanosuspension by Suspended-State NMR and Raman Spectroscopies. Molecular Pharmaceutics, 12, 1564- 1572. https://doi.org/10.1021/mp500872g
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[11]
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Pireddu, R., Sinico, C., Ennas, G., et al. (2015) Novel Nanosized Formulations of Two Diclofenac Acid Polymorphs to Improve Topical Bioavailability. European Journal of Pharmaceutical Sciences, 77, 208-215.
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[12]
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Wu, L., Zhang, J. and Watanabe, W. (2011) Physical and Chemical Stability of Drug Nanoparticles. Advanced Drug Delivery Reviews, 63, 456-469.
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[13]
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Ali, H.S., York, P. and Blagden, N. (2009) Preparation of Hydrocortisone Nanosuspension through a Bottom-Up Nanoprecipitation Technique Using Microfluidic Reactors. International Journal of Pharmaceutics, 375, 107-113.
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[14]
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谢向阳, 陈晨, 廖祥茹, 韩亮. 纳米混悬剂的物理稳定性研究进展[J]. 国际药学研究杂志, 2011, 1(5): 369-374.
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[15]
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Taneja, S., Shilpi, S. and Khatri, K. (2016) Formulation and Optimization of Efavirenz Nanosuspensions Using the Precipitation-Ultrasonication Technique for Solubility Enhancement. Artificial Cells, Nanomedicine, and Biotechnology, 44, 978-984.
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[16]
|
Yong, L., Zhao, X., Zu, Y., et al. (2015) Preparation and Characterization of Paclitaxel Nanosuspension Using Novel Emulsification Method by Combining High Speed Homogenizer and High Pressure Homogenization. International Journal of Pharmaceutics, 490, 324-333.
|
[17]
|
Lou, H., Liu, M., Qu, W., et al. (2013) The Influence of Sodium Salts (Iodide, Chloride And Sulfate) on the Formation Efficiency of Sulfamerazine Nanocrystals. Pharmaceutical Development & Technology, 19, 548-555.
https://doi.org/10.3109/10837450.2013.805777
|
[18]
|
Mishra, B., Sahoo, J. and Dixit, P.K. (2016) Enhanced Bioavailability of Cinnarizine Nanosuspensions by Particle Size Engineering: Optimization and Physicochemical Investigations. Materials Science & Engineering C: Materials for Biological Applications, 63, 62-69.
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[19]
|
George, M. and Ghosh, I. (2012) Identifying the Correlation Between Drug/Stabilizer Properties and Critical Quality Attributes (CQAs) of Nanosuspension Formulation Prepared by wet Media Milling Technology. European Journal of Pharmaceutical Sciences, 48, 142-152.
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[20]
|
Ezhilarasi, P.N., Karthik, P., Chhanwal, N., et al. (2013) Nanoencapsulation Techniques for Food Bioactive Components: A Review. Food and Bioprocess Technology, 6, 628-647. https://doi.org/10.1007/s11947-012-0944-0
|
[21]
|
Meriskoliversidge, E. and Liversidge, G.G. (2011) Nanosizing for Oral and Parenteral Drug Delivery: A Perspective on Formulating Poorly-Water Soluble Compounds Using Wet Media Milling Technology. Advanced Drug Delivery Reviews, 63, 427-440.
|
[22]
|
Liu, D., Xu, H., Tian, B., et al. (2012) Fabrication of Carvedilol Nanosuspensions through the Anti-Solvent Precipitation-Ultrasonication Method for the Improvement of Dissolution Rate and Oral Bioavailability. AAPS PharmSciTech, 13, 295-304. https://doi.org/10.1208/s12249-011-9750-7
|
[23]
|
Hong, C., Dang, Y., Lin, G., et al. (2014) Effects of Stabilizing Agents on the Development of Myricetin Nanosuspension and Its Characterization: An in Vitro and in Vivo Evaluation. International Journal of Pharmaceutics, 477, 251- 260.
|
[24]
|
He, W., Lu, Y., Qi, J., et al. (2013) Food Proteins as Novel Nanosuspension Stabilizers for Poorly Water-Soluble Drugs. International Journal of Pharmaceutics, 441, 269-278.
|
[25]
|
Bi, Y., Liu, J., Wang, J., et al. (2015) Particle Size Control and the Interactions between Drug and Stabilizers in an Amorphous Nanosuspension System. Journal of Drug Delivery Science & Technology, 29, 167-172.
|
[26]
|
Zhang, Y., Furyk, S., Bergbreiter, D.E., et al. (2005) Specific Ion Effects on the Water Solubility of Macromolecules: PNIPAM and the Hofmeister Series. Journal of the American Chemical Society, 127, 14505-14510.
https://doi.org/10.1021/ja0546424
|
[27]
|
Van, E.B., Froyen, L., Van, H.J., et al. (2008) Drying of Crystalline Drug Nanosuspensions—The Importance of Surface Hydrophobicity on Dissolution Behavior upon Redispersion. European Journal of Pharmaceutical Sciences, 35, 127-135.
|
[28]
|
Zhang, Y. and Cremer, P.S. (2006) Interactions between Macromolecules and Ions: The Hofmeister Series. Current Opinion in Chemical Biology, 10, 658-663.
|
[29]
|
Lee, J., Lee, S.J., Choi, J.Y., et al. (2005) Amphiphilic Amino Acid Copolymers as Stabilizers for the Preparation of Nanocrystal Dispersion. European Journal of Pharmaceutical Sciences, 24, 441-449.
|
[30]
|
Ploehn, H.J. and Russel, W.B. (1990) Interactions between Colloidal Particles and Soluble Polymers. Advances in Chemical Engineering, 15, 137-228.
|
[31]
|
Keck, C.M. and Müller, R.H. (2006) Drug Nanocrystals of Poorly Soluble Drugs Produced by High Pressure Homogenisation. European Journal of Pharmaceutics & Biopharmaceutics, 62, 3-16.
|
[32]
|
Möschwitzer, J., Achleitner, G., Pomper, H., et al. (2004) Development of an Intravenously Injectable Chemically Stable Aqueous Omeprazole Formulation Using Nanosuspension Technology. European Journal of Pharmaceutics & Biopharmaceutics, 58, 615-619.
|
[33]
|
Yang, H., Teng, F., Wang, P., et al. (2014) Investigation of a Nanosuspension Stabilized by Soluplus® to Improve Bioavailability. International Journal of Pharmaceutics, 477, 88-95.
|
[34]
|
Ahuja, M., Dhake, A.S., Sharma, S.K., et al. (2011) Diclofenac-Loaded Eudragit S100 Nanosuspension for Ophthalmic Delivery. Journal of Microencapsulation, 28, 37-45. https://doi.org/10.3109/02652048.2010.523794
|
[35]
|
Jacobs, C. and Müller, R.H. (2002) Production and Characterization of a Budesonide Nanosuspension for Pulmonary Administration. Pharmaceutical Research, 19, 189-194. https://doi.org/10.1023/A:1014276917363
|
[36]
|
Zakir, F., Sharma, H., Kaur, K., et al. (2011) Nanocrystallization of Poorly Water Soluble Drugs for Parenteral Administration. Journal of Biomedical Nanotechnology, 7, 127-129. https://doi.org/10.1166/jbn.2011.1234
|
[37]
|
Raula, J., Rahikkala, A., Halkola, T., et al. (2013) Coated Particle Assemblies for the Concomitant Pulmonary Administration of Budesonide and Salbutamol Sulphate. International Journal of Pharmaceutics, 441, 248-254.
|
[38]
|
Du, J., Zhou, Y., Wang, L., et al. (2016) Effect of PEGylated Chitosan as Multifunctional Stabilizer for Deacetyl Mycoepoxydience Nanosuspension Design and Stability Evaluation. Carbohydrate Polymers, 153, 471-481.
|
[39]
|
Sharma, P., Zujovic, Z.D., Bowmaker, G.A., et al. (2011) Evaluation of a Crystalline Nanosuspension: Polymorphism, Process Induced Transformation and in Vivo Studies. International Journal of Pharmaceutics, 408, 138-151.
|
[40]
|
Hasegawa, Y., Higashi, K., Yamamoto, K., et al. (2015) Direct Evaluation of Molecular States of Piroxicam/Polox- amer Nanosuspension by Suspended-State NMR and Raman Spectroscopies. Molecular Pharmaceutics, 12, 1564- 1572. https://doi.org/10.1021/mp500872g
|
[41]
|
Pireddu, R., Sinico, C., Ennas, G., et al. (2015) Novel Nanosized Formulations of Two Diclofenac Acid Polymorphs to Improve Topical Bioavailability. European Journal of Pharmaceutical Sciences, 77, 208-215.
|
[42]
|
Wu, L., Zhang, J. and Watanabe, W. (2011) Physical and Chemical Stability of Drug Nanoparticles. Advanced Drug Delivery Reviews, 63, 456-469.
|
[43]
|
Ali, H.S., York, P. and Blagden, N. (2009) Preparation of Hydrocortisone Nanosuspension through a Bottom-Up Nanoprecipitation Technique Using Microfluidic Reactors. International Journal of Pharmaceutics, 375, 107-113.
|
[44]
|
谢向阳, 陈晨, 廖祥茹, 韩亮. 纳米混悬剂的物理稳定性研究进展[J]. 国际药学研究杂志, 2011, 1(5): 369-374.
|
[45]
|
Taneja, S., Shilpi, S. and Khatri, K. (2016) Formulation and Optimization of Efavirenz Nanosuspensions Using the Precipitation-Ultrasonication Technique for Solubility Enhancement. Artificial Cells, Nanomedicine, and Biotechnology, 44, 978-984.
|
[46]
|
Yong, L., Zhao, X., Zu, Y., et al. (2015) Preparation and Characterization of Paclitaxel Nanosuspension Using Novel Emulsification Method by Combining High Speed Homogenizer and High Pressure Homogenization. International Journal of Pharmaceutics, 490, 324-333.
|
[47]
|
Lou, H., Liu, M., Qu, W., et al. (2013) The Influence of Sodium Salts (Iodide, Chloride And Sulfate) on the Formation Efficiency of Sulfamerazine Nanocrystals. Pharmaceutical Development & Technology, 19, 548-555.
https://doi.org/10.3109/10837450.2013.805777
|
[48]
|
Mishra, B., Sahoo, J. and Dixit, P.K. (2016) Enhanced Bioavailability of Cinnarizine Nanosuspensions by Particle Size Engineering: Optimization and Physicochemical Investigations. Materials Science & Engineering C: Materials for Biological Applications, 63, 62-69.
|
[49]
|
George, M. and Ghosh, I. (2012) Identifying the Correlation Between Drug/Stabilizer Properties and Critical Quality Attributes (CQAs) of Nanosuspension Formulation Prepared by wet Media Milling Technology. European Journal of Pharmaceutical Sciences, 48, 142-152.
|
[50]
|
Ezhilarasi, P.N., Karthik, P., Chhanwal, N., et al. (2013) Nanoencapsulation Techniques for Food Bioactive Components: A Review. Food and Bioprocess Technology, 6, 628-647. https://doi.org/10.1007/s11947-012-0944-0
|
[51]
|
Meriskoliversidge, E. and Liversidge, G.G. (2011) Nanosizing for Oral and Parenteral Drug Delivery: A Perspective on Formulating Poorly-Water Soluble Compounds Using Wet Media Milling Technology. Advanced Drug Delivery Reviews, 63, 427-440.
|
[52]
|
Liu, D., Xu, H., Tian, B., et al. (2012) Fabrication of Carvedilol Nanosuspensions through the Anti-Solvent Precipitation-Ultrasonication Method for the Improvement of Dissolution Rate and Oral Bioavailability. AAPS PharmSciTech, 13, 295-304. https://doi.org/10.1208/s12249-011-9750-7
|
[53]
|
Hong, C., Dang, Y., Lin, G., et al. (2014) Effects of Stabilizing Agents on the Development of Myricetin Nanosuspension and Its Characterization: An in Vitro and in Vivo Evaluation. International Journal of Pharmaceutics, 477, 251- 260.
|
[54]
|
He, W., Lu, Y., Qi, J., et al. (2013) Food Proteins as Novel Nanosuspension Stabilizers for Poorly Water-Soluble Drugs. International Journal of Pharmaceutics, 441, 269-278.
|
[55]
|
Bi, Y., Liu, J., Wang, J., et al. (2015) Particle Size Control and the Interactions between Drug and Stabilizers in an Amorphous Nanosuspension System. Journal of Drug Delivery Science & Technology, 29, 167-172.
|
[56]
|
Zhang, Y., Furyk, S., Bergbreiter, D.E., et al. (2005) Specific Ion Effects on the Water Solubility of Macromolecules: PNIPAM and the Hofmeister Series. Journal of the American Chemical Society, 127, 14505-14510.
https://doi.org/10.1021/ja0546424
|
[57]
|
Van, E.B., Froyen, L., Van, H.J., et al. (2008) Drying of Crystalline Drug Nanosuspensions—The Importance of Surface Hydrophobicity on Dissolution Behavior upon Redispersion. European Journal of Pharmaceutical Sciences, 35, 127-135.
|
[58]
|
Zhang, Y. and Cremer, P.S. (2006) Interactions between Macromolecules and Ions: The Hofmeister Series. Current Opinion in Chemical Biology, 10, 658-663.
|
[59]
|
Lee, J., Lee, S.J., Choi, J.Y., et al. (2005) Amphiphilic Amino Acid Copolymers as Stabilizers for the Preparation of Nanocrystal Dispersion. European Journal of Pharmaceutical Sciences, 24, 441-449.
|
[60]
|
Ploehn, H.J. and Russel, W.B. (1990) Interactions between Colloidal Particles and Soluble Polymers. Advances in Chemical Engineering, 15, 137-228.
|