[1]
|
Hunter, D.J. and Bierma-Zeinstra, S. (2019) Osteoarthritis. The Lancet, 393, 1745-1759. https://doi.org/10.1016/S0140-6736(19)30417-9
|
[2]
|
Bortoluzzi, A., Furini, F. and Scirè, C.A. (2018) Osteoarthritis and Its Management-Epidemiology, Nutritional Aspects and Environmental Factors. Autoimmunity Reviews, 17, 1097-1104. https://doi.org/10.1016/j.autrev.2018.06.002
|
[3]
|
Long, H., Liu, Q., Yin, H., et al. (2022) Prevalence Trends of Site-Specific Osteoarthritis from 1990 to 2019: Findings from the Global Burden of Disease Study 2019. Arthritis & Rheumatology, 74, 1172-1183. https://doi.org/10.1002/art.42089
|
[4]
|
Grässel, S. and Muschter, D. (2020) Recent Advances in the Treatment of Osteoarthritis. F1000Research, 9, Article 325. https://doi.org/10.12688/f1000research.22115.1
|
[5]
|
An, S., Hu, H., Li, Y., et al. (2020) Pyroptosis Plays a Role in Osteoarthritis. Aging and Disease, 11, 1146-1157. https://doi.org/10.14336/AD.2019.1127
|
[6]
|
Shen, P., Jia, S., Wang, Y., et al. (2022) Mechanical Stress Protects Against Chondrocyte Pyroptosis through Lipoxin A4 via Synovial Macrophage M2 Subtype Polarization in an Osteoarthritis Model. Biomedicine & Pharmacotherapy, 153, Article 113361. https://doi.org/10.1016/j.biopha.2022.113361
|
[7]
|
Yao, X., Sun, K., Yu, S., et al. (2021) Chondrocyte Ferroptosis Contribute to the Progression of Osteoarthritis. Journal of Orthopaedic Translation, 27, 33-43. https://doi.org/10.1016/j.jot.2020.09.006
|
[8]
|
Zhang, S., Xu, J., Si, H., et al. (2022) The Role Played by Ferroptosis in Osteoarthritis: Evidence Based on Iron Dyshomeostasis and Lipid Peroxidation. Antioxidants, 11, Article 1668. https://doi.org/10.3390/antiox11091668
|
[9]
|
Wang, W., Chen, Z. and Hua, Y. (2023) Bioinformatics Prediction and Experimental Validation Identify a Novel Cuproptosis-Related Gene Signature in Human Synovial Inflammation during Osteoarthritis Progression. Biomolecules, 13, Article 127. https://doi.org/10.3390/biom13010127
|
[10]
|
Huang, Y.F., Wang, G., Ding, L., et al. (2023) Lactate-Upregulated NADPH-Dependent NOX4 Expression via HCAR1/PI3K Pathway Contributes to ROS-Induced Osteoarthritis Chondrocyte Damage. Redox Biology, 67, Article 102867. https://doi.org/10.1016/j.redox.2023.102867
|
[11]
|
Sasaki, E., Yamamoto, H., Matsuta, R., et al. (2022) Metabolomics of Osteoarthritis with Synovitis in Middle Aged Women from the Iwaki Health Promotion Project. Osteoarthritis and Cartilage, 30, S96-S97. https://doi.org/10.1016/j.joca.2022.02.122
|
[12]
|
Lambrecht, S., Verbruggen, G., Verdonk, P.C.M., et al. (2008) Differential Proteome Analysis of Normal and Osteoarthritic Chondrocytes Reveals Distortion of Vimentin Network in Osteoarthritis. Osteoarthritis and Cartilage, 16, 163-173. https://doi.org/10.1016/j.joca.2007.06.005
|
[13]
|
Liu, X., Olszewski, K., Zhang, Y., et al. (2020) Cystine Transporter Regulation of Pentose Phosphate Pathway Dependency and Disulfide Stress Exposes a Targetable Metabolic Vulnerability in Cancer. Nature Cell Biology, 22, 476-486. https://doi.org/10.1038/s41556-020-0496-x
|
[14]
|
Liu, X., Nie, L., Zhang, Y., et al. (2023) Actin Cytoskeleton Vulnerability to Disulfide Stress Mediates Disulfidptosis. Nature Cell Biology, 25, 404-414. https://doi.org/10.1038/s41556-023-01091-2
|
[15]
|
Woetzel, D., Huber, R., Kupfer, P., et al. (2014) Identification of Rheumatoid Arthritis and Osteoarthritis Patients by Transcriptome-Based Rule Set Generation. Arthritis Research & Therapy, 16, Article No. R84. https://doi.org/10.1186/ar4526
|
[16]
|
Broeren, M.G.A., De Vries, M., Bennink, M.B., et al. (2016) Functional Tissue Analysis Reveals Successful Cryopreservation of Human Osteoarthritic Synovium. PLOS ONE, 11, e0167076. https://doi.org/10.1371/journal.pone.0167076
|
[17]
|
Guo, Y., Walsh, A.M., Fearon, U., et al. (2017) CD40L-Dependent Pathway Is Active at Various Stages of Rheumatoid Arthritis Disease Progression. Journal of Immunology, 198, 4490-4501. https://doi.org/10.4049/jimmunol.1601988
|
[18]
|
Leek, J.T., Johnson, W.E., Parker, H.S., et al. (2023) sva: Surrogate Variable Analysis. https://bioconductor.org/packages/sva
|
[19]
|
Ritchie, M.E., Phipson, B., Wu, D., et al. (2015) Limma Powers Differential Expression Analyses for RNA-Sequencing and Microarray Studies. Nucleic Acids Research, 43, e47. https://doi.org/10.1093/nar/gkv007
|
[20]
|
Greenacre, M., Groenen, P.J.F., Hastie, T., et al. (2022) Principal Component Analysis. Nature Reviews Methods Primers, 2, Article No. 100. https://doi.org/10.1038/s43586-022-00184-w
|
[21]
|
Lê, S., Josse, J. and Husson, F. (2008) FactoMineR: An R Package for Multivariate Analysis. Journal of Statistical Software, 25, 1-18. https://doi.org/10.18637/jss.v025.i01
|
[22]
|
Wilkerson, M.D. and Hayes, D.N. (2010) ConsensusClusterPlus: A Class Discovery Tool with Confidence Assessments and Item Tracking. Bioinformatics, 26, 1572-1573. https://doi.org/10.1093/bioinformatics/btq170
|
[23]
|
Villanueva, R.A.M. and Chen, Z.J. (2019) Ggplot2: Elegant Graphics for Data Analysis (2nd Ed.). Measurement: Interdisciplinary Research and Perspectives, 17, 160-167. https://doi.org/10.1080/15366367.2019.1565254
|
[24]
|
Hänzelmann, S., Castelo, R. and Guinney, J. (2013) GSVA: Gene Set Variation Analysis for Microarray and RNA-Seq Data. BMC Bioinformatics, 14, Article No. 7. https://doi.org/10.1186/1471-2105-14-7
|
[25]
|
Jassal, B., Matthews, L., Viteri, G., et al. (2020) The Reactome Pathway Knowledgebase. Nucleic Acids Research, 48, D498-D503. https://doi.org/10.1093/nar/gkz1031
|
[26]
|
Ashburner, M., Ball, C.A., Blake, J.A., et al. (2000) Gene Ontology: Tool for the Unification of Biology. Nature Genetics, 25, 25-29. https://doi.org/10.1038/75556
|
[27]
|
Wu, T., Hu, E., Xu, S., et al. (2021) ClusterProfiler 4.0: A Universal Enrichment Tool for Interpreting Omics Data. The Innovation, 2, Article 100141. https://doi.org/10.1016/j.xinn.2021.100141
|
[28]
|
Kanehisa, M., Furumichi, M., Tanabe, M., et al. (2017) KEGG: New Perspectives on Genomes, Pathways, Diseases and Drugs. Nucleic Acids Research, 45, D353-D361. https://doi.org/10.1093/nar/gkw1092
|
[29]
|
Karatzoglou, A., Smola, A., Hornik, K., et al. (2004) Kernlab—An S4 Package for Kernel Methods in R. Journal of Statistical Software, 11, 1-20. https://doi.org/10.18637/jss.v011.i09
|
[30]
|
Liaw, A. and Wiener, M. (2002) Classification and Regression by randomForest. The R Journal, 2, 18-22.
|
[31]
|
Zheng, P., Zhou, C., Ding, Y., et al. (2023) Disulfidptosis: A New Target for Metabolic Cancer Therapy. Journal of Experimental & Clinical Cancer Research, 42, Article No. 103. https://doi.org/10.1186/s13046-023-02675-4
|
[32]
|
Liu, H., Deng, Z., Yu, B., et al. (2022) Identification of SLC3A2 as a Potential Therapeutic Target of Osteoarthritis Involved in Ferroptosis by Integrating Bioinformatics, Clinical Factors and Experiments. Cells, 11, Article 3430. https://doi.org/10.3390/cells11213430
|
[33]
|
Elsasser, S., Gali, R.R., Schwickart, M., et al. (2002) Proteasome Subunit Rpn1 Binds Ubiquitin-Like Protein Domains. Nature Cell Biology, 4, 725-730. https://doi.org/10.1038/ncb845
|
[34]
|
You, K., Wang, L., Chou, C.H., et al. (2021) QRICH1 Dictates the Outcome of ER Stress through Transcriptional Control of Proteostasis. Science, 371, eabb6896. https://doi.org/10.1126/science.abb6896
|
[35]
|
Cao, Q., Hong, A., Shen, R., et al. (2023) Disulfidptosis-Related NCK Associated Protein 1 as a Potential Biomarker for Multiple Tumor Types: A Pan-Cancer Analysis Based on Public Databases. https://www.researchsquare.com
|
[36]
|
Shi, M., Wang, J., Xiao, Y., et al. (2018) Glycogen Metabolism and Rheumatoid Arthritis: The Role of Glycogen Synthase 1 in Regulation of Synovial Inflammation via Blocking AMP-Activated Protein Kinase Activation. Frontiers in Immunology, 9, Article 1714. https://www.frontiersin.org/articles/10.3389/fimmu.2018.01714 https://doi.org/10.3389/fimmu.2018.01714
|
[37]
|
Mccorvie, T.J., Loria, P.M., Tu, M., et al. (2022) Molecular Basis for the Regulation of Human Glycogen Synthase by Phosphorylation and Glucose-6-Phosphate. Nature Structural & Molecular Biology, 29, 628-638. https://doi.org/10.1038/s41594-022-00799-3
|
[38]
|
Kohan, A.B., Talukdar, I., Walsh, C.M., et al. (2009) A Role for AMPK in the Inhibition of Glucose-6-Phosphate Dehydrogenase by Polyunsaturated Fatty Acids. Biochemical and Biophysical Research Communications, 388, 117-121. https://doi.org/10.1016/j.bbrc.2009.07.130
|
[39]
|
Yen, W.C., Wu, Y.H., Wu, C.C., et al. (2020) Impaired Inflammasome Activation and Bacterial Clearance in G6PD Deficiency Due to Defective NOX/P38 MAPK/AP-1 Redox Signaling. Redox Biology, 28, Article 101363. https://doi.org/10.1016/j.redox.2019.101363
|
[40]
|
Kawai, T. and Akira, S. (2007) Signaling to NF-κB by Toll-Like Receptors. Trends in Molecular Medicine, 13, 460-469. https://doi.org/10.1016/j.molmed.2007.09.002
|
[41]
|
Zhang, G. and Ghosh, S. (2001) Toll-Like Receptor-Mediated NF-κB Activation: A Phylogenetically Conserved Paradigm in Innate Immunity. The Journal of Clinical Investigation, 107, 13-19. https://doi.org/10.1172/JCI11837
|
[42]
|
Schütze, S., Wiegmann, K., Machleidt, T., et al. (1995) TNF-Induced Activation of NF-κB. Immunobiology, 193, 193-203. https://doi.org/10.1016/S0171-2985(11)80543-7
|
[43]
|
Wang, C.Y., Mayo, M.W. and Baldwin, A.S. (1996) TNF-and Cancer Therapy-Induced Apoptosis: Potentiation by Inhibition of NF-κB. Science, 274, 784-787. https://doi.org/10.1126/science.274.5288.784
|
[44]
|
Hayden, M.S. and Ghosh.S. (2014) Regulation of NF-κB by TNF Family Cytokines. Seminars in Immunology, 26, 253-266. https://doi.org/10.1016/j.smim.2014.05.004
|
[45]
|
Gu, F.M., Li, Q.L., Gao, Q., et al. (2011) IL-17 Induces AKT-Dependent IL-6/JAK2/STAT3 Activation and Tumor Progression in Hepatocellular Carcinoma. Molecular Cancer, 10, Article No. 150. https://doi.org/10.1186/1476-4598-10-150
|
[46]
|
Hu, Z., Luo, D., Wang, D., et al. (2017) IL-17 Activates the IL-6/STAT3 Signal Pathway in the Proliferation of Hepatitis B Virus-Related Hepatocellular Carcinoma. Cellular Physiology and Biochemistry, 43, 2379-2390. https://doi.org/10.1159/000484390
|
[47]
|
Sun, M., Sheng, H., Wu, T., et al. (2021) PIKE-A Promotes Glioblastoma Growth by Driving PPP Flux through Increasing G6PD Expression Mediated by Phosphorylation of STAT3. Biochemical Pharmacology, 192, Article 114736. https://doi.org/10.1016/j.bcp.2021.114736
|
[48]
|
Piao, Y.J., Seo, Y.H., Hong, F., et al. (2005) Nox 2 Stimulates Muscle Differentiation via NF-κB/INOS Pathway. Free Radical Biology and Medicine, 38, 989-1001. https://doi.org/10.1016/j.freeradbiomed.2004.11.011
|
[49]
|
Pérez, L., Vallejos, A., Echeverria, C., et al. (2019) OxHDL Controls LOX-1 Expression and Plasma Membrane Localization through a Mechanism Dependent on NOX/ROS/NF-κB Pathway on Endothelial Cells. Laboratory Investigation, 99, 421-437. https://doi.org/10.1038/s41374-018-0151-3
|
[50]
|
Manea, A., Tanase, L.I., Raicu, M., et al. (2010) JAK/STAT Signaling Pathway Regulates Nox1 and Nox4-Based NADPH Oxidase in Human Aortic Smooth Muscle Cells. Arteriosclerosis, Thrombosis, and Vascular Biology, 30, 105-112. https://doi.org/10.1161/ATVBAHA.109.193896
|
[51]
|
Braunersreuther, V., Montecucco, F., Ashri, M., et al. (2013) Role of NADPH Oxidase Isoforms NOX1, NOX2 and NOX4 in Myocardial Ischemia/Reperfusion Injury. Journal of Molecular and Cellular Cardiology, 64, 99-107. https://doi.org/10.1016/j.yjmcc.2013.09.007
|
[52]
|
Tschopp, J. and Schroder, K. (2010) NLRP3 Inflammasome Activation: The Convergence of Multiple Signalling Pathways on ROS Production? Nature Reviews Immunology, 10, 210-215. https://doi.org/10.1038/nri2725
|
[53]
|
Snelling, S., Sinsheimer, J.S., Carr, A., et al. (2007) Genetic Association Analysis of LRCH1 as an Osteoarthritis Susceptibility Locus. Rheumatology, 46, 250-252. https://doi.org/10.1093/rheumatology/kel265
|
[54]
|
Sanchez, D. and Ganfornina, M.D. (2021) The Lipocalin Apolipoprotein D Functional Portrait: A Systematic Review. Frontiers in Physiology, 12, Article 738991. https://doi.org/10.3389/fphys.2021.738991
|
[55]
|
Li, C., Ding, H., Tian, J., et al. (2016) Forkhead Box Protein C2 Promotes Epithelial-Mesenchymal Transition, Migration and Invasion in Cisplatin-Resistant Human Ovarian Cancer Cell Line (SKOV3/CDDP). Cellular Physiology and Biochemistry, 39, 1098-1110. https://doi.org/10.1159/000447818
|
[56]
|
Lin, F., Li, X., Wang, X., et al. (2022) Stanniocalcin 1 Promotes Metastasis, Lipid Metabolism and Cisplatin Chemoresistance via the FOXC2/ITGB6 Signaling Axis in Ovarian Cancer. Journal of Experimental & Clinical Cancer Research, 41, Article No. 129. https://doi.org/10.1186/s13046-022-02315-3
|
[57]
|
Stobdan, T., Zhou, D., Ao-Ieong, E., et al. (2015) Endothelin Receptor B, a Candidate Gene from Human Studies at High Altitude, Improves Cardiac Tolerance to Hypoxia in Genetically Engineered Heterozygote Mice. Proceedings of the National Academy of Sciences, 112, 10425-10430. https://doi.org/10.1073/pnas.1507486112
|
[58]
|
Zhou, J., Deo, B.K., Hosoya, K., et al. (2005) Increased JNK Phosphorylation and Oxidative Stress in Response to Increased Glucose Flux through Increased GLUT1 Expression in Rat Retinal Endothelial Cells. Investigative Ophthalmology & Visual Science, 46, 3403-3410. https://doi.org/10.1167/iovs.04-1064
|
[59]
|
Jiang, X., Deng, X., Wang, J., et al. (2022) BPIFB1 Inhibits Vasculogenic Mimicry via Downregulation of GLUT1-Mediated H3K27 Acetylation in Nasopharyngeal Carcinoma. Oncogene, 41, 233-245. https://doi.org/10.1038/s41388-021-02079-8
|
[60]
|
Spector, T.D., Reneland, R.H., Mah, S., et al. (2006) Association between a Variation InLRCH1 and Knee Osteoarthritis: A Genome-Wide Single-Nucleotide Polymorphism Association Study Using DNA Pooling. Arthritis & Rheumatism, 54, 524-532. https://doi.org/10.1002/art.21624
|
[61]
|
Liu, C., Xu, X., Han, L., et al. (2020) LRCH1 Deficiency Enhances LAT Signalosome Formation and CD8 T Cell Responses against Tumors and Pathogens. Proceedings of the National Academy of Sciences, 117, 19388-19398. https://doi.org/10.1073/pnas.2000970117
|
[62]
|
Koenig, A. and Buskiewicz-Koenig, I.A. (2022) Redox Activation of Mitochondrial DAMPs and the Metabolic Consequences for Development of Autoimmunity. Antioxidants & Redox Signaling, 36, 441-461. https://doi.org/10.1089/ars.2021.0073
|
[63]
|
Vitry, G., Paulin, R., Grobs, Y., et al. (2021) Oxidized DNA Precursors Cleanup by NUDT1 Contributes to Vascular Remodeling in Pulmonary Arterial Hypertension. American Journal of Respiratory and Critical Care Medicine, 203, 614-627. https://doi.org/10.1164/rccm.202003-0627OC
|
[64]
|
Agarwal, S. and De Jesus Perez, V.A. (2021) In Defense of the Nucleus: NUDT1 and Oxidative DNA Damage in Pulmonary Arterial Hypertension. American Journal of Respiratory and Critical Care Medicine, 203, 541-542. https://doi.org/10.1164/rccm.202009-3706ED
|