[1]
|
Shi, Y.L., Chen, Z.Y., Zhao, Z.H., et al. (2019) IL-21 Induces an Imbalance of Th17/Treg Cells in Moderate-to-Severe Plaque Psoriasis Patients. Frontiers in Immunology, 10, Article 1865. https://doi.org/10.3389/fimmu.2019.01865
|
[2]
|
Di Cesare, A., Di Meglio, P. and Nestle, F.O. (2009) The IL-23/Th17 Axis in the Immunopathogenesis of Psoriasis. Journal of Investigative Dermatology, 129, 1339-1350. https://doi.org/10.1038/jid.2009.59
|
[3]
|
Yang, L.T., Li, B., Dang, E.L., et al. (2016) Impaired Function of Regulatory T Cells in Patients with Psoriasis Is Mediated by Phosphorylation of STAT3. Journal of Dermatological Science, 81, 85-92.
https://doi.org/10.1016/j.jdermsci.2015.11.007
|
[4]
|
Miyoshi, K., Takaishi, M., Nakajima, K., et al. (2011) Stat3 as a Therapeutic Target for the Treatment of Psoriasis: A Clinical Feasibility Study with STA-21, a Stat3 Inhibitor. Journal of Investigative Dermatology, 131, 108-117.
https://doi.org/10.1038/jid.2010.255
|
[5]
|
Yang, L.T., Jin, L., Ke, Y., et al. (2018) E3 Ligase Trim21 Ubiquitylates and Stabilizes Keratin 17 to Induce STAT3 Activation in Psoriasis. Journal of Investigative Dermatology, 138, 2568-2577.
https://doi.org/10.1016/j.jid.2018.05.016
|
[6]
|
Rapp, S.R., Feldman, S.R., Exum, M.L., et al. (1999) Psoriasis Causes as Much Disability as Other Major Medical Diseases. Journal of the American Academy of Dermatology, 41, 401-407.
https://doi.org/10.1016/S0190-9622(99)70112-X
|
[7]
|
于研, 刘晓洁, 张峻岭. 白细胞介素-17抑制剂在银屑病中的应用进展[J]. 中国中西医结合皮肤性病学杂志, 2022, 21(5): 472-476.
|
[8]
|
Li, B.B., He, S.C., Liu, R., et al. (2019) Total Glucosides of Paeony Attenuates Animal Psoriasis Induced Inflammatory Response through Inhibiting STAT1 and STAT3 Phosphorylation. Journal of Ethnopharmacology, 243, Article ID: 112121. https://doi.org/10.1016/j.jep.2019.112121
|
[9]
|
刘芳, 庞晓文, 张萍, 等. 银屑病患者血清IL-6、IL-25、IL-31表达及其临床意义[J]. 中国临床医学, 2022, 29(6): 987-991.
|
[10]
|
Parrish-Novak, J., Dillon, S.R., et al. (2000) Interleukin21 and Its Receptor Are Involved in NK Cell Expansion and Regulation of Lymphocyte Function. Nature, 408, 57-63. https://doi.org/10.1038/35040504
|
[11]
|
Frhlich, C., Ehrhardt, J., Krüger, D., et al. (2020) Pregnancy Status Alters IL-21-Mediated Effects on Murine B Lymphocytes. Reproduction, 159, 351-359. https://doi.org/10.1530/REP-19-0407
|
[12]
|
Long, D., Chen, Y.J., Wu, H.J., Zhao, M. and Lu, Q.J. (2019) Clinical Significance and Immunobiology of IL-21 in Autoimmunity. Journal of Autoimmunity, 111, 1-14. https://doi.org/10.1016/j.jaut.2019.01.013
|
[13]
|
吕萌, 沈萃萃. 银屑病患者外周血滤泡辅助性T细胞比例、血清IL-21水平变化及其与病情的关系[J]. 山东医药, 2018, 58(8): 93-95.
|
[14]
|
吴越阳, 铁璐. IL-21参与银屑病表皮增生过程[J]. 生理科学进展, 2010(1): 21.
|
[15]
|
薛国辉, 华琳, 刘晓峰, 等. 外周血循环滤泡辅助性T细胞及IL-21在银屑病中的表达及意义[J]. 中国免疫学杂志, 2016, 32(11): 1645-1648, 1652.
|
[16]
|
Caruso, R., Bott, E., Sarra, M., et al. (2009) Involvement of Interleukin-21 in the Epidermal Hyperplasia of Psoriasis. Nature Medicine, 15, 1013-1015. https://doi.org/10.1038/nm.1995
|
[17]
|
Costanzo, A., Chimenti, M.S., Botti, E., et al. (2010) IL-21 in the Pathogenesis and Treatment of Skin Diseases. Journal of Dermatological Science, 60, 61-66. https://doi.org/10.1016/j.jdermsci.2010.08.016
|
[18]
|
胡萍, 何丽, 申焕君, 等. IL-21与疾病关系的研究进展[J]. 细胞与分子免疫学杂志, 2014, 30(9): 996-999.
|
[19]
|
李思彤. 滤泡性辅助性T细胞、IL-21及B细胞对HaCaT细胞增殖及细胞周期的影响[D]: [硕士学位论文]. 北京: 北京协和医学院, 2021.
|
[20]
|
Wilmsen, P.K., Spada, D.S. and Salvador, M. (2005) Antioxidant Activity of the Flavonoid Hesperidin in Chemical and Biological Systems. Journal of Agricultural and Food Chemistry, 53, 4757-4761.
https://doi.org/10.1021/jf0502000
|
[21]
|
Li, S.M., Sang, S.M., Pan, M.H., et al. (2007) Anti-Inflammatory Property of the Urinary Metabolites of Nobiletin in Mouse. Bioorganic & Medicinal Chemistry Letters, 17, 5177-5181. https://doi.org/10.1016/j.bmcl.2007.06.096
|
[22]
|
Miyazawa, M., Okuno, Y., Fukuyama, M., Nakamura, S. and Kosaka, H. (1999) Antimutagenic Activity of Polymethoxyflavonoids from Citrus aurantium. Journal of Agricultural and Food Chemistry, 47, 5239-5244.
https://doi.org/10.1021/jf990176o
|
[23]
|
Guthrie, N., Kurowska, E.M. and Manthey, J.A. (2010) Compositions and Methods of Treating, Reducing and Preventing Cardiovascular Diseases and Disorders with Polymethoxyflavones. US Patent No. WO2001070029A1.
|
[24]
|
Walle, T. (2007) Methoxylated Flavones,a Superior Cancer Chemopreventive Flavonoid Subclass? Seminars in Cancer Biology, 17, 354-362. https://doi.org/10.1016/j.semcancer.2007.05.002
|
[25]
|
刘中兵. 川陈皮素抑制IL-21/IL-21R介导类风湿关节炎的炎症反应研究[D]: [博士学位论文]. 苏州: 苏州大学, 2020.
|
[26]
|
Zhang, Q., Song, X., Chen, X., et al. (2021) Antiosteoporotic Effect of Hesperidin against Ovariectomy-Induced Osteoporosis in Rats via Reduction of Oxidative Stress and Inflammation. Journal of Biochemical and Molecular Toxicology, 35, e22832. https://doi.org/10.1002/jbt.22832
|
[27]
|
周铭, 马丽华, 崔颖, 等. 雷公藤甲素对类风湿性关节炎患者外周血T细胞的免疫抑制作用[J]. 中国药房, 2014, 25(47): 4441-4443.
|
[28]
|
王小强, 刘刚. 芪藤地黄颗粒联合雷公藤多苷片治疗Ⅳ期糖尿病肾病的研究[J]. 现代中西医结合杂志, 2015(19): 2060-2064.
|
[29]
|
张榕, 吴春玲, 李舒帆, 等. 雷公藤多苷联合来氟米特治疗老年活动性类风湿关节炎的疗效[J]. 中国老年学杂志, 2011(12): 2194-2196.
|
[30]
|
陈晶晶, 赵巧萍. 雷公藤多苷片联合低分子肝素钙治疗小儿紫癜性肾炎的临床疗效及免疫调节机制研究[J]. 儿科药学杂志, 2015, 21(6): 32-35.
|
[31]
|
孙凤艳, 姜淑华, 平利峰, 等. 雷公藤多苷对类风湿关节炎患者滤泡辅助性T细胞及IL-21的影响[J]. 医学综述, 2016(3): 566-569.
|
[32]
|
杨培花, 范娟, 马格. 雷公藤多苷对儿童紫癜性肾炎TGF-β1和IL-21表达的影响以及临床价值研究[J]. 中国中西医结合肾病杂志, 2016, 17(4): 341-342.
|
[33]
|
Wang, Y.Q., Dai, M., Zhong, J.C. and Yin, D.K. (2012) Paeonol Inhibits Oxidized Low Density Lipoprotein-Induced Monocyte Adhesion to Vascular Endothelial Cells by Inhibiting the Mitogen Activated Protein Kinase Pathway. Biological & Pharmaceutical Bulletin, 35, 767-772. https://doi.org/10.1248/bpb.35.767
|
[34]
|
郭琳, 郭伟. 英丹皮酚制剂不同给药途径在家兔体内的药动学研究[J]. 辽宁医学院学报, 2007, 28(4): 4-8.
|
[35]
|
刘霞. 丹皮酚对溃疡性结肠炎的治疗效果及机制研究[D]: [博士学位论文]. 郑州: 郑州大学, 2017.
|
[36]
|
于磊, 唐尧, 张蕊, 等. 肝苏颗粒治疗慢性乙型肝炎的系统评价[J]. 中国药业, 2012, 21(10): 20-22.
|
[37]
|
唐奇远, 何清, 白冰, 等. 肝苏治疗慢性乙型肝炎的系统评价[J]. 中国循证医学杂志, 2010, 10(8): 978-984.
|
[38]
|
Ma, S.W., Huang, X., Li, Y.Y., et al. (2012) High Serum IL-21 Levels after 12 Weeks of Antiviral Therapy Predict HBeAg Seroconversion in Chronic Hepatitis B. Journal of Hepatology, 56, 775-781.
https://doi.org/10.1016/j.jhep.2011.10.020
|
[39]
|
邹敏, 李珉珉, 李晓娟, 等. 不同治疗方案对慢性乙型肝炎患者血清白介素21水平的影响[J]. 南方医科大学学报, 2012, 32(9): 1284-1286, 1289.
|
[40]
|
莫菁莲, 王政. 肝苏颗粒对慢性乙型肝炎患者IL-21的影响[J]. 中国实验方剂学杂志, 2013, 19(8): 284-286.
|
[41]
|
马琴国, 李天庆. 紫草化学成分及药理作用研究进展[J]. 甘肃中医学院学报, 2013, 30(2): 78-80.
|
[42]
|
王勋. 紫草素调控白细胞介素-6治疗肺动脉高压的机制研究[D]: [硕士学位论文]. 衡阳: 南华大学, 2021.
|
[43]
|
Tao, T.J., Chen, Y., Lai, B.C., et al. (2022) Shikonin Combined with Methotrexate Regulate Macrophage Polarization to Treat Psoriasis. Bioengineered, 13, 11146-11155. https://doi.org/10.1080/21655979.2022.2062090
|
[44]
|
Shao, K.F., Guan, F.G., and Dong, C. (2021) [Clinical Effect and Mechanism of Total Glucosides of Paeony in the Adjuvant Therapy for Children with Henoch-Schönlein Purpura Nephritis: A Prospective Randomized Controlled Study]. Chinese Journal of Contemporary Pediatrics, 23, 49-54.
|
[45]
|
Wang, Y.N., Zhang, Y., Wang, Y., et al. (2013) The Beneficial Effect of Total Glucosides of Paeony on Psoriatic Arthritis Links to Circulating Tregs and Th1 Cell Function. Phytotherapy Research, 28, 372-381.
https://doi.org/10.1002/ptr.5005
|
[46]
|
Li, H., Cao, X.Y., Dang, W.Z., et al. (2019) Total Glucosides of Paeony Protects against Collagen-Induced Mouse Arthritis via Inhibiting Follicular Helper T Cell Differentiation. Phytomedicine, 65, Article ID: 153091.
https://doi.org/10.1016/j.phymed.2019.153091
|
[47]
|
Kerstin, W., Ellen, W., Elizabeth, W., et al. (2006) IL-22 Regulates the Expression of Genes Responsible for Antimicrobial Defense, Cellular Differentiation, and Mobility in Keratinocytes: A Potential Role in Psoriasis. European Journal of Immunology, 36, 1309-1323. https://doi.org/10.1002/eji.200535503
|
[48]
|
Yan, Z., Dimitry, M.D., Patricia, V., et al. (2007) Interleukin-22, a TH17 Cytokine, Mediates IL-23-Induced Dermal Inflammation and Acanthosis. Nature, 445, 648-651. https://doi.org/10.1038/nature05505
|
[49]
|
Hueber, W., Patel, D.D., Dryja, T., et al. (2010) Effects of AIN457, a Fully Human Antibody to Interleukin-17 A, on Psoriasis, Rheumatoid Arthritis and Uveitis. Science Translational Medicine, 2, 52-72.
https://doi.org/10.1126/scitranslmed.3001107
|