[1]
|
Asthma Group of Chinese Throacic Society (2020) Guidelines for Bronchial Asthma Prevent and Management (2020 Edition). Chinese Journal of Tuberculosis and Respiratory Diseases, 43, 1023-1048.
|
[2]
|
Soriano, J.B., et al. (2020) Prevalence and Attributable Health Burden of Chronic Respiratory Diseases, 1990-2017: A Systematic Analysis for the Global Burden of Disease Study 2017. The Lancet Respiratory Medicine, 8, 585-596.
|
[3]
|
Viegi, G., Maio, S., Fasola, S. and Baldacci, S. (2020) Global Burden of Chronic Respiratory Diseases. Journal of Aerosol Medicine and Pulmonary Drug Delivery, 33, 171-177. https://doi.org/10.1089/jamp.2019.1576
|
[4]
|
Huang, K., Yang, T., Xu, J., et al. (2019) Prevalence, Risk Factors, and Management of Asthma in China: A National Cross-Sectional Study. The Lancet, 394, 407-418. https://doi.org/10.1016/S0140-6736(19)31147-X
|
[5]
|
Fahy, J.V. (2015) Type 2 Inflammation in Asthma—Present in Most, Absent in Many. Nature Reviews Immunology, 15, 57-65. https://doi.org/10.1038/nri3786
|
[6]
|
Boonpiyathad, T., et al. (2019) Immunologic Mechanisms in Asthma. Sem-inars in Immunology, 46, Article ID: 101333.
https://doi.org/10.1016/j.smim.2019.101333
|
[7]
|
Pain, M., Bermudez, O., Lacoste, P., et al. (2014) Tissue Re-modelling in Chronic Bronchial Diseases: From the Epithelial to Mesenchymal Phenotype. European Respiratory Review, 23, 118-130.
https://doi.org/10.1183/09059180.00004413
|
[8]
|
游曼清, 王宋平. 气道上皮屏障在支气管哮喘防御机制中的研究进展[J]. 中华哮喘杂志(电子版), 2013, 7(5): 345-349.
|
[9]
|
Manzanares, D., Gonzalez, C., Ivonnet, P., et al. (2011) Functional Apical Large Conductance, Ca2+-Activated, and Voltage-Dependent K+ Channels Are Required for Maintenance of Airway Surface Liquid Volume. Journal of Biological Chemistry, 286, 19830-19839. https://doi.org/10.1074/jbc.M110.185074
|
[10]
|
Nicolas, P. (2009) Multifunctional Host Defense Peptides: Intra-cellular-Targeting Antimicrobial Peptides. The FEBS Journal, 276, 6483-6496. https://doi.org/10.1111/j.1742-4658.2009.07359.x
|
[11]
|
Kuperman, D.A., Huang, X., Koth, L.L., et al. (2002) Direct Effects of Interleukin-13 on Epithelial Cells Cause Airway Hyperreactivity and Mucus Overproduction in Asthma. Nature Medicine, 8, 885-889.
https://doi.org/10.1038/nm734
|
[12]
|
Evans, C., Kim, K., Tuvim, M.J. and Dickey, B.F. (2009) Mucus Hypersecretion in Asthma: Causes and Effects. Current Opinion in Pulmonary Medicine, 15, 4-11. https://doi.org/10.1097/MCP.0b013e32831da8d3
|
[13]
|
Kirkham, S., Sheehan, J.K., Knight, D., Richardson, P.S. and Thornton, D.J. (2002) Heterogeneity of Airways Mucus: Variations in the Amounts and Glycoforms of the Major Oligomeric Mucins MUC5AC and MUC5B. Biochemical Journal, 361, 537-546. https://doi.org/10.1042/bj3610537
|
[14]
|
Zaragosi, L., Deprez, M. and Barbry, P. (2020) Using Single-Cell RNA Sequencing to Unravel Cell Lineage Relationships in the Respiratory Tract. Biochemical Society Transactions, 48, 327-336. https://doi.org/10.1042/BST20191010
|
[15]
|
Ma, J., Rubin, B.K. and Voynow, J.A. (2018) Mucins, Mucus, and Goblet Cells. Chest Journal, 154, 169-176.
https://doi.org/10.1016/j.chest.2017.11.008
|
[16]
|
Loxham, M., Davies, D.E. and Blume, C. (2014) Epithelial Function and Dysfunction in Asthma. Clinical & Experimental Allergy, 44, 1299-1313. https://doi.org/10.1111/cea.12309
|
[17]
|
Gon, Y. and Hashimoto, S. (2018) Role of Airway Epithelial Barrier Dysfunction in Pathogenesis of Asthma. Allergology International, 67, 12-17. https://doi.org/10.1016/j.alit.2017.08.011
|
[18]
|
Campbell, H.K., Maiers, J.L. and DeMali, K.A. (2017) Interplay between Tight Junctions & Adherens Junctions. Experimental Cell Research, 358, 39-44. https://doi.org/10.1016/j.yexcr.2017.03.061
|
[19]
|
Walko, G., Castañón, M.J. and Wiche, G. (2015) Molecular Architecture and Function of the Hemidesmosome. Cell and Tissue Research, 360, 529-544. https://doi.org/10.1007/s00441-015-2216-6
|
[20]
|
Georas, S.N. and Rezaee, F. (2014) Epithelial Barrier Function: At the Front Line of Asthma Immunology and Allergic Airway Inflammation. The Journal of Allergy and Clinical Immunology, 134, 509-520.
https://doi.org/10.1016/j.jaci.2014.05.049
|
[21]
|
Nawijn, M.C., Hackett, T.L., Postma, D.S., et al. (2011) E-Cadherin: Gatekeeper of Airway Mucosa and Allergic Sensitization. Trends in Immunology, 32, 248-255. https://doi.org/10.1016/j.it.2011.03.004
|
[22]
|
Jacquet, A. (2011) Interactions of Airway Epithelium with Protease Allergens in the Allergic Response. Clinical & Experimental Allergy, 41, 305-311. https://doi.org/10.1111/j.1365-2222.2010.03661.x
|
[23]
|
Sajjan, U., et al. (2008) Rhinovirus Disrupts the Barrier Function of Polarized Airway Epithelial Cells. American Journal of Respiratory and Critical Care Medicine, 178, 1271-1281. https://doi.org/10.1164/rccm.200801-136OC
|
[24]
|
Shepley-Mc Taggart, A., Sagum, C.A., Oliva, I., et al. (2021) SARS-CoV-2 Envelope (E) Protein Interacts with PDZ-Domain-2 of Host Tight Junction Protein ZO1. PLoS ONE, 16, e0251955.
https://doi.org/10.1371/journal.pone.0251955
|
[25]
|
Martens, K., Pugin, B., De Boeck, I., et al. (2018) Probiotics for the Airways: Potential to Improve Epithelial and Immune Homeostasis. Allergy, 73, 1954-1963. https://doi.org/10.1111/all.13495
|
[26]
|
Forteza, R.M., Casalino-Matsuda, S.M., Falcon, N.S., et al. (2012) Hyaluronan and Layilin Mediate Loss of Airway Epithelial Barrier Function Induced by Cigarette Smoke by Decreasing E-Cadherin. Journal of Biological Chemistry, 287, 42288-42298. https://doi.org/10.1074/jbc.M112.387795
|
[27]
|
Yamamoto, N., et al. (2021) Incense Smoke-Induced Oxidative Stress Disrupts Tight Junctions and Bronchial Epithelial Barrier Integrity and Induces Airway Hyperresponsiveness in Mouse Lungs. Scientific Reports, 11, Article No. 7222. https://doi.org/10.1038/s41598-021-86745-7
|
[28]
|
崔海洋, 马壮, 孙文武. 冷空气诱发支气管哮喘的研究进展[J]. 中华肺部疾病杂志(电子版), 2016, 9(5): 558-561.
|
[29]
|
Zhou, J., Zhou, X.D., Xu, R., et al. (2021) The Degradation of Airway Epithelial Tight Junctions in Asthma under High Airway Pressure Is Probably Mediated by Piezo-1. Frontiers in Physiology, 12, Article ID: 637790.
https://doi.org/10.3389/fphys.2021.637790
|
[30]
|
李敏超, 尤列•皮尔曼, 周向东. MARCKS磷酸化对冷刺激诱导人气道上皮细胞MUC5AC分泌的影响[J]. 中南大学学报(医学版), 2012, 37(5): 447-452.
|
[31]
|
Lambrecht, B.N. and Hammad, H. (2014) Immunology, Allergens and the Airway Epithelium Response: Gateway to Allergic Sensitization. The Journal of Allergy and Clinical Immunology, 134, 499-507.
https://doi.org/10.1016/j.jaci.2014.06.036
|
[32]
|
Xiao, C., et al. (2011) Defective Epithelial Barrier Function in Asthma. The Journal of Allergy and Clinical Immunology, 128, 549-556.E12. https://doi.org/10.1016/j.jaci.2011.05.038
|
[33]
|
Sweerus, K., et al. (2017) Claudin-18 Deficiency Is Associated with Airway Epithelial Barrier Dysfunction and Asthma. The Journal of Allergy and Clinical Immunology, 139, 72-81.E1. https://doi.org/10.1016/j.jaci.2016.02.035
|
[34]
|
Lee, P.H., Kim, B.G., Lee, S.H., et al. (2018) Alteration in Claudin-4 Contributes to Airway Inflammation and Responsiveness in Asthma. Allergy, Asthma & Immunology Research, 10, 25-33.
|
[35]
|
Kumamoto, J., Tsutsumi, M., Goto, M., et al. (2016) Japanese Cedar (Cryptomeria japonica) Pollen Allergen Induces Elevation of Intracellular Calcium in Human Keratinocytes and Impairs Epidermal Barrier Function of Human Skin ex Vivo. Archives of Dermatological Research, 308, 49-54. https://doi.org/10.1007/s00403-015-1602-y
|
[36]
|
Saito, T., Ichikawa, T., Numakura, T., et al. (2021) PGC-1α Regulates Airway Epithelial Barrier Dysfunction Induced by House Dust Mite. Respiratory Research, 22, Article No. 63. https://doi.org/10.1186/s12931-021-01672-5
|
[37]
|
周峥嵘, 等. PGC-1α研究进展[J]. 江苏大学学报(医学版), 2018, 28(4): 362-366.
|
[38]
|
Dong, H.M., Le, Y.Q., Wang, Y.H., et al. (2017) Extracellular Heat Shock Protein 90α Mediates HDM-Induced Bronchial Epithelial Barrier Dysfunction by Activating RhoA/MLC Signaling. Respiratory Research, 18, Article No. 111.
https://doi.org/10.1186/s12931-017-0593-y
|
[39]
|
Rezaee, F., Meednu, N., Emo, J.A., et al. (2011) Polyinosinic: Polycytidylic Acid Induces Protein Kinase D-Dependent Disassembly of Apical Junctions and Barrier Dysfunction in Airway Epithelial Cells. The Journal of Allergy and Clinical Immunology, 128, 1216-1224.E11. https://doi.org/10.1016/j.jaci.2011.08.035
|
[40]
|
Kicic, A., et al. (2016) Impaired Airway Epithelial Cell Responses from Children with Asthma to Rhinoviral Infection. Clinical & Experimental Allergy, 46, 1441-1455. https://doi.org/10.1111/cea.12767
|
[41]
|
Hasan, S., Sebo, P. and Osicka, R. (2018) A Guide to Polarized Airway Epithelial Models for Studies of Host-Pathogen Interactions. The FEBS Journal, 285, 4343-4358. https://doi.org/10.1111/febs.14582
|
[42]
|
Wang, H., He, L., Liu, B., et al. (2018) Establishment and Comparison of Air-Liquid Interface Culture Systems for Primary and Immortalized Swine Tracheal Epithelial Cells. BMC Cell Biology, 19, Article No. 10.
https://doi.org/10.1186/s12860-018-0162-3
|
[43]
|
Ladjemi, M., et al. (2018) Bronchial Epithelial IgA Secretion Is Impaired in Asthma. Role of IL-4/IL-13. American Journal of Respiratory and Critical Care Medicine, 197, 1396-1409. https://doi.org/10.1164/rccm.201703-0561OC
|
[44]
|
Hu, Y., et al. (2017) TSLP Signaling Blocking Alleviates E-Cadherin Dysfunction of Airway Epithelium in a HDM-Induced Asthma Model. Cellular Immunology, 315, 56-63. https://doi.org/10.1016/j.cellimm.2017.02.003
|
[45]
|
柴园园, 徐佳雨, 刘莉. 气道上皮细胞在哮喘肺部炎症中的屏障作用和免疫调节作用[J]. 医学综述, 2021, 27(13): 2509-2515.
|
[46]
|
Sekiyama, A., Gon, Y., Terakedo, M., et al. (2012) Glucocorticoids Enhance Airway Epithelial Barrier Integrity. International Immunopharmacology, 12, 350-357. https://doi.org/10.1016/j.intimp.2011.12.006
|
[47]
|
Coraux, C., Kileztky, C., Polette, M., et al. (2004) Airway Epithelial Integrity Is Protected by a Long-Acting Beta2-Adrenergic Receptor Agonist. American Journal of Respiratory Cell and Molecular Biology, 30, 605-612.
https://doi.org/10.1165/rcmb.2003-0056OC
|
[48]
|
Trinh, H., Pham, D., Choi, Y., et al. (2018) Epithelial Folliculin Enhances Airway Inflammation in Aspirin-Exacerbated Respiratory Disease. Clinical & Experimental Allergy, 48, 1464-1473. https://doi.org/10.1111/cea.13253
|
[49]
|
Yuan, X., Wang, J., Li, Y., et al. (2018) Allergy Immunotherapy Restores Airway Epithelial Barrier Dysfunction through Suppressing IL-25-Induced Endoplasmic Reticulum Stress in Asthma. Scientific Reports, 8, Article No. 7950.
https://doi.org/10.1038/s41598-018-26221-x
|
[50]
|
Richards, L.B., Li, M., Folkerts, G., et al. (2020) Butyrate and Propionate Restore the Cytokine and House Dust Mite Compromised Barrier Function of Human Bronchial Airway Epithelial Cells. International Journal of Molecular Sciences, 22, Article No. 65. https://doi.org/10.3390/ijms22010065
|