基本情况

王久存（Jiucun Wang），复旦大学生命科学学院副教授。任复旦大学现代人类学教育部重点实验室科研主管，复旦大学泰州健康科学研究院研究员、复旦大学风湿、免疫、过敏性疾病研究中心副主任。

研究领域

肺癌等肿瘤致病机理的遗传学及表观遗传学研究、硬皮病等自身免疫性疾病的基因组学研究及分子致病机理研究

教育背景

1999年 博士，日本福井大学

1991年 硕士，复旦大学

1988年 学士，复旦大学

论文发表

1. Wang JC, Sonnylal S, Arnett FC, de Crombrugghe B, Zhou X. Attenuation of gene expression of extracellular matrix elements with siRNAs of Sparc and Ctgf in cultured skin fibroblasts from Ctgf transgenic mice. International Journal of Immunopathology and Pharmacology. In press.
2. Liu Q, Yao F, Wang M, Zhou B, Cheng H, Wang W, Jin L, Lin Q, Wang JC*. Novel human BTB/POZ domain-containing zinc finger protein ZBTB1 inhibits transcriptional activities of CRE. Mol Cell Biochem. 2011 Jun 25. [Epub ahead of print]
3. Jiang Y, Wang W, Wang J, Lu Y, Chen Y, Jin L, Lin D, He F, Wang H. Functional regulatory variants of MCL1 contribute to enhanced promoter activity and reduced risk of lung cancer in non-smokers. Cancer. In press
4. Wang JC, Lai S, Guo X, Zhang X, de Crombrugghe B, Arnett FC, Zhou X. Attenuation of fibrosis in vitro and in vivo with Sparc siRNA. Arthritis Res Ther. 2010;12(2):R60
5. Hua R, Xu JB, Wang JC, Zhu L, Li B, Liu Y, Huang SD, Jin L, Xu ZY, Wang XF. Association of TNFAIP3 polymorphism with rheumatic heart disease in Chinese Han population. Immunogenetics. 2009;61(11-12):739-44
6. Wang YL, Wang JC*, Wu Y, Zhang L, Huang CP, Shen Q, Zhu YX, Li DS, Ji QH*. Incidentally simultaneous occurrence of RET/PTC, H4-PTEN and BRAF mutation in papillary thyroid carcinoma. Cancer Letters. 2008. 34(1):77-81
7. Wang JC, Su CC, Xu JB, Chen LZ, Hu XH, Wang GY, Bao Y, Huang Q, Fu SB, Li P, Lu CQ, Zhang RM, Luo ZW. A novel microdeletion in the transforming growth factor β type II receptor gene (TGFBR2) is associated with giant and large cell variants of non-small cell lung carcinoma. Genes, Chromosomes and Cancer. 2007. 46: 192-201
8. Xu JB, Bao Y, Liu X, Liu Y, Huang HD, Wang JC*. Defective expression of transforming growth factor-β type II receptor (TGFBR2) in the large cell variant of non-small cell lung carcinoma. Lung Cancer. 2007. 58 (1):36-43