基本情况
冯红,四川大学生命科学学院教授,博士生导师;中国遗传学会微生物遗传专委会委员和四川省遗传学会理事及微生物及生物技术专业委员会主任;先后主持国家863、国家支撑计划、自然科学基金等多项研究。
研究领域
分子微生物学、生物技术
工作经历
2004年12月至至今,四川大学生命科学学院任教,从事教学与科研工作。
2001年12月至2004年9月,美国Clemson University遗传学与生物化学系博士后,参与美国国家卫生研究院(NIH)项目的研究。
2000年7月至2001年12月,成都百奥生物信息科技有限公司研发部经理,负责主持公司的科技研究发展工作。
1988年7月至1997年9月,四川农业大学任教,从事教学与科研工作。
论文发表
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Liu Y-C, Han L-L, Chen T-Y, Lu Y-B, Feng H*. (2020) Characterization of a protease hyper-productive mutant of Bacillus pumilus by comparative genomic and transcriptomic analysis. Curr Microbiol. 77: 3612-3622.
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Miao Cui-Cui, Han Lin-Li, Lu Yan-Bing, Feng Hong* (2020) Construction of a high-expression system in Bacillus through transcriptomic profiling and promoter engineering. Microorganisms. 8:103.
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Liu G, Jiang Y-M, Liu Y-C, Han L-L, Feng H* (2020) A novel DNA methylation motif identified in Bacillus pumilus BA06 and possible roles in the regulation of gene expression. Appl. Microbiol. Biotechnol. 104:3445-3457.
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Yong B, Fei X, Shao H, Xu P, Hu Y, Ni W, Xiao Q, Tao X, He X, Feng H* (2020) Recombinant expression and biochemical characterization of a novel keratinase BsKer71 from feather degrading bacterium Bacillus subtilis S1-4. AMB Express. 10:9.
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Wu L-Y, Xu J-J, Xu P, Yong B, Feng H*. (2019) Enhancement of soluble expression and biochemical characterization of two epoxide hydrolases from Bacillus. Iran J Biotech. 17(2):e2189.
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Han L-L, Liu Y-C, Miao C-C, Feng H*. (2019). Disruption of the pleiotropic gene scoC causes transcriptomic and phenotypical changes in Bacillus pumilus BA06. BMC Genomics. 20,327.
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杨诗明,梁波,王新星,冯红. (2018)重组人角质细胞生长因子-2工程菌的发酵条件研究.生物过程.8(2):40-47.
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Zhao H-Y, Feng H*. (2018) Engineering Bacillus pumilus alkaline serine protease to increase its low-temperature proteolytic activity by directed evolution. BMC Biotechnology. 18:34.
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李雷,冯红*. (2018) 两株芽孢杆菌降解羽毛比较及抗氧化肽分离. 应用与环境生物学报. 24(1):0172-0176.
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Li L, Xie T, Liu Z, Feng H*, Wang G*. (2018) Activity enhancement of CotA laccase by hydrophilic engineering, histidine tag optimization and static culture. Prot. Eng. Des. Sel. 31(1):1-5.
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Han, Lin-Li, Huan-Huan Shao, Yong-Cheng Liu, Gang Liu, Chao-Ying Xie, Xiao-Jie Cheng, Hai-Yan Wang, Xue-Mei Tan and Feng H* (2017) Transcriptome profiling analysis reveals metabolic changes across various growth phases in Bacillus pumilus BA06. BMC Microbiology. 17:156.
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Cheng X-J, He B, Chen L, Xiao S-Q, Fu J, Chen Y, Yu T-Q, Cheng Z-Q, Feng H*. (2016) Transcriptome analysis confirms a complex disease resistance network in wild rice Oryza meyeriana against Xanthomonas oryzae pv. oryzae. Scientific Reports. 6:38215.
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Zhao H-Y, Wu L-Y, Liu G, Feng H* (2016) Single-site substitutions improve cold activity and increase thermostability of the dehairing alkaline protease (DHAP). Biosci Biotech Biochem. 80(12), 2480-2485.
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Dong G, M-X He, Feng H* (2016) Functional characterization of CRISPR-Cas system in the ethanologenic bacterium Zymomonas mobilis ZM4. Adv Microbiol. 6: 178-189.
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Wan M-Y, Dong G, Yang B-Q, Feng H* (2016) Identification and characterization of a novel antioxidant peptide from feather keratin hydrolysate. Biotech Lett. 38(4): 643-649.
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Wang XC, Zhao HY, Liu G, Cheng XJ, Feng H*. (2016) Improving production of extracellular proteases by random mutagenesis and biochemical characterization of a serine protease in Bacillus subtilis S1-4. Genetics and Molecular Research. 15(2): gmr.15027831.
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姬杨,冯红*. (2016) 短小芽孢杆菌BA06产表面活性培养基组分的优化. 四川大学学报(自然版). 53(4):925-930.
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黄蓉, 冯红*. (2015) 脱毛碱性蛋白酶(DHAP)的饱和突变. 四川大学学报(自然版). 52(5):1177-1181.
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Huang R, Yang Q, Feng H*. (2015) Single amino acid mutation alters thermostability of the alkaline protease from Bacillus pumilus: thermodynamics and temperature dependence. Acta Biochim. Biophys. Sin. 47(2): 98-105.
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Shao H, Cao Q, Zhao, H, Tan X, Feng H* (2015) Construction of novel shuttle expression vectors for gene expression in Bacillus subtilis and Bacillus pumilus. J. Gen. Appl. Microbiol. 61(2): 124-131.
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Jing Z, Feng H*(2015) Studies on the molecular docking and amino acid residues involving in recognition of substrate in proline iminopeptidase by site-directed mutagenesis. Protein J. 34(3):173-180.
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Liu RF, Huang CL, Feng H* (2015) Salt stress represses production of extracellular proteases in Bacillus pumilus. Genet. Mol. Res. 14(2): 4339-4948.
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Zhang K, Shao H, Cao Q, He M-X, Wu B, Feng H* (2015) Transcriptional analysis of adaptation to high glucose concentrations in Zymomonas mobilis. Appl. Microbiol. Biotechnol. 99(4), 2009-2022.