基本情况
戴克胜,北京航空航天大学“蓝天学者”特聘教授、苏州大学“特聘教授”,苏州大学附属第一医院、江苏省血液研究所教授、博士生导师,血栓与止血研究室副主任。
研究领域
血栓与止血,细胞信号转导及凋亡调控机制
论文发表
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Suping Li, Zhicheng Wang, Yi
Liao, Weilin Zhang, Quanwei Shi, Rong Yan, Changgeng Ruan, Kesheng Dai*. The
glycoprotein Ibalpha-von Willebrand factor interaction induces platelet
apoptosis. Journal of Thrombosis and Haemostasis 2010, 8: 341-50. (IF2009:
6.069)
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Zhicheng Wang, Quanwei Shi,
Rong Yan, Guanglei Liu, Weilin Zhang, Kesheng Dai*. The role of calpain in the
regulation of ADAM17-dependent GPIb ectodomain shedding. Archives of Biochemistry and Biophysics 2010, 495:
136-143. (IF2009: 3.046)
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Suping Li, Quanwei Shi,
Guanglei Liu, Weilin Zhang, Zhicheng Wang, Yuedan Wang, Kesheng Dai*. Mechanism
of platelet functional changes and the effects of anti-platelet agents on in
vivo hemostasis under different gravity conditions. Journal of Applied Physiology
2010, 108: 1241-1249. (IF2009: 3.732)
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Zhicheng Wang, Quanwei Shi,
Suping Li, Juan Du, Jun Liu, Kesheng Dai*. Hyperthermia induces platelet
apoptosis and glycoprotein Ibα ectodomain
shedding. Platelets 2010, 21: 229-237. (IF2009: 2.272)
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Zhicheng Wang, Suping Li,
Quanwei Shi, Rong Yan, Guanglei Liu, Kesheng Dai*. Calmodulin antagonists
induce platelet apoptosis. Thrombosis Research 2010, 125: 340-350. (IF2009:
2.406)
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Guoming Li, Qiang Cheng,
Kesheng Dai, Xiaofeng Zheng. The Ca2+-dependent multimerization of Homo sapiens
S100 domain in Cornulin protects cells from injury. Progress in Biochemistry
and Biophysics 2010, (e-pub ahead of print). (IF2009:0.193)
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Guoming Li, Linglong Qu,Geng
Meng, Xiaoyun Bai, Kesheng Dai and Xiaofeng Zheng. Crystallization and
preliminary X-ray crystallographic studies of human FAIM protein. Structural
Biology and Crystallization Communications 2010, F66: 935–937. (IF2009:0.551)
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Yanhong Yuan, Weilin Zhang,
Rong Yan, Yi Liao, Lili Zhao, Changgeng Ruan, Xiaoping Du, Kesheng Dai*.
Identification of a novel 14-3-3ζ binding site within the cytoplasmic domain of platelet glycoprotein
Ib that plays a key role in regulating the VWF binding function of
glycoprotein Ib-IX. Circulation Research 2009, 105: 1177-85. (IF2009: 9.214)
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Kesheng Dai*, Yuedan Wang,
Rong Yan, Quanwei Shi, Zhicheng Wang, Yanhong Yuan, Hong Cheng, Suping Li, Yubo
Fan, Fengyuan Zhuang. Effects of microgravity and hypergravity on platelet
function. Thrombosis and Haemostasis 2009, 101: 902-910. (Cover, Editorial focus)(IF2009: 4.451)
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Hong Cheng, Suping Li,
Yanhong Yuan, Rong Yan, Changgeng Ruan, Kesheng Dai*. Shear-induced von
Willebrand factor-dependent platelet glycoprotein Ibα shedding. The American Journal of
Physiology-Heart and Circulatory Physiology 2009, 297: H2128-35. (IF2009: 3.712)
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Rong Yan, Zhicheng Wang,
Yanhong Yuan, Hong Cheng, Kesheng Dai*. Role of cAMP-dependent protein kinase
in the regulation of platelet procoagulant activity. Archives of Biochemistry
and Biophysics 2009, 485: 41-48. (IF2009: 3.046)
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Suping Li, Quanwei Shi,
Zhicheng Wang, Rong Yan, Hong Cheng, Kesheng Dai*. Hypergravity Results in
Human Platelet Hyperactivity. Journal of Physiology and Biochemistry 2009, 65:
147-156. (IF2009: 0.891)
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Rong Yan, Suping Li, Kesheng
Dai*. The critical roles for cyclic AMP/cyclic AMP-dependent protein kinase in
platelet physiology. Frontiers of Biology in China, 2009; 4: 7-14.
(Review)
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Kesheng Dai*, Rong Yan,
Suping Li, Yubo Fan, Fengyuan Zhuang, Changgeng Ruan. Prolonged inhibition of
protein kinase A results in the dysfunction of platelet by GPIb shedding. Thrombosis Research 2009, 124: 101-109. (IF2009:
2.406)
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G. Li, Z. Tang, G. Meng, K.
Dai, J. Zhao and X. Zheng. Crystallization and preliminary X-ray
crystallographic studies of O-methyltransferase from Anabaena PCC 7120. Acta
Cryst Structural Biology and Crystallization Communications 2009; F65: 1039-41.
(IF2009: 0.606)
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Kesheng Dai, Richard J.
Bodnar, Michael C. Berndt, Xiaoping Du. A critical role for 14-3-3 protein
in platelet adhesion and its therapeutic implications. Blood 2005, 106:
1975-1981. (IF2009: 10.555)
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Kesheng Dai, Huaiping Zhu,
Changgeng Ruan. Construction, expression and characterization of a single chain
Fv specific against platelets GP Ibα. Thrombosis Research 2003; 109: 137-144. (IF2009: 2.406)
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Kesheng Dai, Weiqing Gao,
Changgeng Ruan. The Sma I polymorphism in the von Willebrand factor gene
associated with acute ischemic stroke. Thrombosis Research 2001; 104: 389-395.
(IF2009: 2.406)
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元艳宏,康佳蕊,闫荣,程虹,庄逢源,王月丹,戴克胜*。血小板膜糖蛋白Ibα第559位丝氨酸磷酸化多克隆抗体制备及应用。中华医学杂志 2009,89:826-830
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戴克胜,阮长耿*。流变与血小板功能(综述)。中国血液流变学杂志 2009,19(2):167-170