基本情况

刘万红,武汉大学基础医学院免疫学系,博士,教授,博士生导师。中华医学会微生物与免疫学分会青年委员会委员、武汉市免疫学会第七届理事会常务理事、湖北省微生物与免疫学会委员、湖北省细胞学会理事、中国免疫学学会会员、中国细胞生物学学会会员、中国微生物学学会会员、国际期刊Infectious Disorders - Drug Targets等杂志编委。曾受邀担任National Science ReviewBBA - Reviews on CancerCancer letterCell Death & DiseaseNanoscaleCellular MicrobiologyJournal of Medical Virology30多种国际期刊杂志审稿专家以及国家自然科学基金通讯评审专家。

 

研究领域

1)研究人泡沫病毒(Human foamy virus, HFV)的感染及其作用机制,以及HFV载体的构建及其在神经系统疾病中的应用。

2)研究肠道病毒71型(Human enterovirus 71, EV71)和柯萨奇病毒A16型(Coxsachievirus A16, CA16)等病毒的感染及其致病机制,特别是其导致手足口病患儿脑部神经系统疾病的作用机理;同时致力于EV71/ CA16病毒新型疫苗和免疫诊断的研发。

 

教育背景

2014.02-2015.02 访问学者,美国Texas A&M University生理与药理学系

2007.03-2008.12 博士后,新加坡国立大学医学院及Temasek Life Sciences Laboratory

2002.09-2005.06 博士,武汉大学微生物学专业

1999.09-2002.07 硕士,武汉大学微生物学专业

1990.09-1994.07 本科,武汉大学病毒学专业

 

论文发表

  1. Chen L, Chen L, Zuo L, Gao Z, Shi Y, Yuan P, Han S, Yin J, Peng B, He X, Liu W*.  Long Noncoding RNA GAS5 Inhibits HIV-1 Replication Through Interaction with miR-873. AIDS Res Hum Retroviruses. 2018 Jun, 34(6): 544-549.
  2. Yuan P, Dong L, Cheng Q, Wang S, Li Z, Sun Y, Han S, Yin J, Peng B, He X, Liu W*. Prototype foamy virus elicits complete autophagy involving the ER stress-related UPR pathway. Retrovirology. 2017 Mar 7, 14(1): 16.
  3. Xu S, Dong L, Shi Y, Chen L, Yuan P, Wang S, Li Z, Sun Y, Han S, Yin J, Peng B, He X, Liu W*. The Novel Landscape of Long Non-coding RNAs in Response to Human Foamy Virus Infection Characterized by RNA-seq. AIDS Res Hum Retroviruses. 2017 May, 33(5): 452-464
  4. Zhou B, Chu M, Xu S, Chen X, Liu Y, Wang Z, Zhang F, Han S, Yin J, Peng B, He X*, Liu W*. Hsa-let-7c-5p augments enterovirus 71 replication through viral subversion of cell signaling in rhabdomyosarcoma cells. Cell Biosci. 2017 Jan 14,  7: 7.
  5. Wang Z, Hu P, Tang F, Lian H, Chen X, Zhang Y, He X, Liu W*, Xie C*. HDAC6 promotes cell proliferation and confers resistance to temozolomide in glioblastoma. Cancer Lett. 2016 Jun 3, 379(1): 134-142.
  6. Shi Y, Tu H, Chen X, Zhang Y, Chen L, Liu Z, Sheng J, Han S, Yin J, Peng B, He X, Liu W*. The long non-coding RNA expression profile of Coxsackievirus A16 infected RD cells identified by RNA-seq. Virol Sin. 2016 Apr, 31(2): 131-41.
  7. Dong L, Cheng Q, Wang Z, Yuan P, Li Z, Sun Y, Han S, Yin J, Peng B, He X*, Liu W*. Human Pirh2 is A Novel Inhibitor of Prototype Foamy Virus Replication. Viruses. 2015 Apr 2, 7(4): 1668-84.
  8. Zhang F, Liu Y, Chen X, Dong L, Zhou B, Cheng Q, Han S, Liu Z, Peng B, He X*, Liu W*. RASSF4 promotes EV71 replication to accelerate the inhibition of the phosphorylation of AKT. Biochem Biophys Res Commun. 2015 Mar 20, 458(4) :810-5.
  9. Li Z#, Liu WH#, Han S, Peng BW, Yin J, Wu YL, He XH*, Li WX*. Selective inhibition of CCR7(-) effector memory T cell activation by a novel peptide targeting Kv1.3 channel in a rat experimental autoimmune encephalomyelitis model. J Biol Chem. 2012 Aug 24, 287(35): 29479-94.
  10. Liu W, Liu Z, Cao X, Cao Z, Xue L, Zhu F, He X*, Li W*. Recombinant human foamy virus, a novel vector for neurological disorders gene therapy, drives production of GAD in cultured astrocytes. Mol Ther. 2007 Oct, 15(10): 1834-41.