基本情况
马翔,华中科技大学同济医院副教授。
教育背景
Jul.2002–Mar.2007, Ph.D,
Department of Pharmacy National University of Singapore
Sept.1998-Jul.2001, M.Sc, Medicinal Chemistry,Department of Medicinal Chemistry
Shanghai Institute of Pharmaceutical Industry,Shanghai, China
Sept.1994–Jun.1998,B.E.,Chemical Pharmaceutics, Department of Chemical
Pharmaceutics School of Pharmaceutical Engineering,Shenyang Pharmaceutical
University,Shenyang, China
工作履历
Jun.2011-current,Associate
Professor,Tongji School of Pharmacy Huazhong University of Science and
Technology,P. R. China
Jan.2010-May.2011,Associate Professor,Shanghai Institute of Pharmaceutical
Industry Shanghai, P. R. China
Jan.2008-Jan.2010,Research Fellow, Department of Pharmacy/Chemical and
Biomolecular Engineering, National University of Singapore,
Singapore
Jul. 2006–Dec.2007, Postdoctoral Research Associate, Biology,
Chemistry and Physics Department, Illinois Institute of Technology (IIT),
Chicago, IL, USA
Jul.2001,-Jun.2002,Research Associate Department of Medicinal
Chemistry Shanghai Institute of Materia Medica Chinese Academy of
Sciences,Shanghai, China
学术兼职
Member, The American
Association of Pharmaceutical Scientists (AAPS)
Member, The American Chemical Society (ACS)
Member, International Society for the Study of Xenobiotics (ISSX)
获得荣誉
The 3rd Asian Pacific
Regional ISSX Meeting, 2009. Best Presenter Award (first place)
Inaugural AAPS-NUS Student Chapter Symposium, 2005, Singapore, Best Presenter
Award
Pharmaceutical Sciences World Congress (PSWC 2004), 2004, Kyoto, Japan, Travel
Grant Winner
主要论文
-
Zichun Ding;
Weicheng Zhou; Xiang Ma*,A facile approach to
synthesize
3-(6-Chloro-thiazolo[5,4-b]pyridin-2-ylmethoxy)-2,6-difluoro-benzamide
(PC190723),Synlett,23 (7), 1039-1042, 2012
-
Zichun Ding; Xiang Ma*; Weicheng Zhou, Convenient and Practical Synthesis of
6-Chloro-2-(Chloromethyl)- Thiazolo[5,4-b]Pyridine, Synthetic Communications,
42 (19), 2791-2796, 2012
-
Xiang Ma*, Guangya Xiang, Chun-Wei Yap, Wai-Keung Chui*, 3D-QSAR Study on
dihydro-1,3,5-triazines and their spiro derivatives as DHFR inhibitors by
comparative molecular field analysis (CoMFA), Bioorganic & Medicinal
Chemistry Letters, 22 (9), 3194-3197, 2012
-
Xiang Ma*, Soo-Tong Tan, Chai-Ling Khoo, Hong-May Sim, Lai-Wah Chan, Wai-Keung
Chui*, Synthesis and antimicrobial activity of N1-benzyl or N1
-benzyloxy-1,6-dihydro-1,3,5-triazine-2,4-diamines, Bioorganic & Medicinal
Chemistry Letters, 21 (18), 5428-5431, 2011
-
Xiang Ma,Eric Chun Yong Chan*.
On-line Chromatographic Screening of Matrix Metalloproteinase Inhibitors using
Immobilized MMP-9 Enzyme Reactor. Journal of Chromatography B, 2010, 878, 1777.
-
Xiang Ma*, Wai-Keung Chui*. Antifolate and Antiproliferative Activity of
6,8,10-Triazaspiro[4.5]deca-6,8-Dienes and
1,3,5-Triazaspiro[5.5]undeca-1,3-Dienes. Bioorganic and Medicinal Chemistry,
2010, 18, 737-743.
-
Xiang Ma, Eric Chun Yong Chan*. Fluorescence-Based Liver Microsomal Assay for
Screening of Pharmaceutical Reactive Metabolites using Glutathione Conjugated
96-Well Plate. Bioconjugate Chem. 2010, 21 (2), 46-55.
-
Xiang Ma, Eric Chun Yong Chan*. Fluorescence-based Screening of Pharmaceutical
Reactive Metabolites Using Glutathione Immobilized 96-Well Microsomal Assay.
Drug Metabol. Rev., 2009; 41(S2): 26.
-
Xiang Ma*, Renee Ser-Peng Woon, Paul Chi-Lui Ho and Wai-Keung Chui*.
Antiproliferative Activity against MCF-7 Breast Cancer Cells by Diamino-Triaza
spirodiene Antifolates. Chemical Biology & Drug Design, 2009, 74, 322-326.
-
Xiang Ma*, Thong-Yuen Poona, Peter TH Wong and Wai-Keung Chui*. Synthesis and
in vitro Evaluation of 2,4-Diamino-1,3,5-Triazines Derivatives as Neuronal
Voltage-Gated Sodium Channel Blockers. Bioorganic & Medicinal Chemistry
Letters, 2009, 19, 5644-5647. (SCI, IF 2.6)
-
Ma Xiang*, Zhou Weicheng,* Brun Reto. Synthesis, in vitro antitrypanomal and
antibacterial activity of phenoxy, phenylthio or benzyloxy substituted
quinolones. Bioorganic & Medicinal Chemistry Letters, 2009, 19, 986-989.
-
Hyun-Soon Chong*, Hyun A Song, Xiang Ma, Sooyoun Lim, Xiang Sun and Santosh
Mhaske. Bile Q1 acid-based polyaminocarboxylate conjugates as targeted
antitumor agents. Chemical Communication, 2009, 21: 3011-3.
-
Hyun-Soon Chong*, Xiang Ma, Thien Le, Baidoo Kwame na, Diane E. Milenic, Erik
D. Brady, Hyun A. Song, Martin W. Brechbiel. Rational Design and Generation of
a Bimodal Bifunctional Ligand for Antibody-Targeted Radiation Cancer Therapy.
J. Med. Chem. 2008, 51, 118–125.
-
Hyun-Soon Chong*, Xiang Ma, Haisung Lee, Phuong Bui, Hyun A. Song, Noah Birch.
Synthesis and Evaluation of Novel Polyaminocarboxylate-Based Antitumor Agents.
J. Med. Chem. 2008, 51, 2208–2215.
-
Hyun-Soon Chong,*, Hyun A. Song, Xiang Ma, Diane E. Milenic, Erik D. Brady,
Sooyoun Lim, Haisung Lee, Kwamena Baidoo, Dengfeng Cheng, Martin W. Brechbiel.
Novel Bimodal Bifunctional Ligands for Radioimmunotherapy and Targeted MRI.
Bioconjugate Chemistry 2008, 19, 1439-1447.
-
Hyun-Soon Chong,* Hyun A. Song, Noah Birch, Thien Le, Sooyoun Lim, Xiang Ma.
Efficient synthesis and evaluation of bimodal ligand NETA. Bioorganic &
Medicinal Chemistry Letters, 2008, 18, 3436-3439.
-
Hyun-Soon Chong,* Hyun A. Song, Sooyoun Lim, Keith Macrenaris, Xiang Ma,
Haisung Lee, Phuong Buia and Thomas Meade. A novel cholic acid-based contrast
enhancement agent for targeted MRI. Bioorganic & Medicinal Chemistry
Letters, 2008, 18, 2505–2508.
-
Kong Kah-Hoe, Chen Yu, Ma Xiang, Chui Wai Keung, Lam Yulin*. Traceless
solid-phase synthesis of nitrogen-containing heterocycles and their biological
evaluations as inhibitors of neuronal sodium channels. Journal of Combinatorial
Chemistry, 2004, 6(6), 928-933.
-
Ma Xiang; Zhou Weicheng*. Progress in research on synthetic antibacterial
agents oxazolidinones. Zhongguo Yiyao Gongye Zazhi (Chinese Journal of
Pharmaceuticals), 2000, 31(8), 370-376.