基本情况

马翔,华中科技大学同济医院副教授。

教育背景
Jul.2002–Mar.2007, Ph.D, Department of Pharmacy National University of Singapore 
Sept.1998-Jul.2001, M.Sc, Medicinal Chemistry,Department of Medicinal Chemistry Shanghai Institute of Pharmaceutical Industry,Shanghai, China
Sept.1994–Jun.1998,B.E.,Chemical Pharmaceutics, Department of Chemical Pharmaceutics School of Pharmaceutical Engineering,Shenyang Pharmaceutical University,Shenyang, China

工作履历
Jun.2011-current,Associate Professor,Tongji School of Pharmacy  Huazhong University of Science and Technology,P. R. China
Jan.2010-May.2011,Associate Professor,Shanghai Institute of Pharmaceutical Industry Shanghai, P. R. China
Jan.2008-Jan.2010,Research Fellow, Department of Pharmacy/Chemical and Biomolecular Engineering,  National University of Singapore,  Singapore
Jul. 2006–Dec.2007, Postdoctoral Research Associate, Biology, Chemistry and Physics Department, Illinois Institute of Technology (IIT), Chicago, IL, USA 
Jul.2001,-Jun.2002,Research Associate Department of Medicinal Chemistry  Shanghai Institute of Materia Medica  Chinese Academy of Sciences,Shanghai, China

学术兼职
Member, The American Association of Pharmaceutical Scientists (AAPS)
Member, The American Chemical Society (ACS)
Member, International Society for the Study of Xenobiotics (ISSX)

获得荣誉
The 3rd Asian Pacific Regional ISSX Meeting, 2009. Best Presenter Award (first place)
Inaugural AAPS-NUS Student Chapter Symposium, 2005, Singapore, Best Presenter Award
Pharmaceutical Sciences World Congress (PSWC 2004), 2004, Kyoto, Japan, Travel Grant Winner

主要论文

  1. Zichun Ding; Weicheng Zhou; Xiang Ma*,A facile approach to synthesize 3-(6-Chloro-thiazolo[5,4-b]pyridin-2-ylmethoxy)-2,6-difluoro-benzamide (PC190723),Synlett,23 (7), 1039-1042, 2012
  2. Zichun Ding; Xiang Ma*; Weicheng Zhou, Convenient and Practical Synthesis of 6-Chloro-2-(Chloromethyl)- Thiazolo[5,4-b]Pyridine, Synthetic Communications, 42 (19), 2791-2796, 2012
  3. Xiang Ma*, Guangya Xiang, Chun-Wei Yap, Wai-Keung Chui*, 3D-QSAR Study on dihydro-1,3,5-triazines and their spiro derivatives as DHFR inhibitors by comparative molecular field analysis (CoMFA), Bioorganic & Medicinal Chemistry Letters, 22 (9), 3194-3197, 2012
  4. Xiang Ma*, Soo-Tong Tan, Chai-Ling Khoo, Hong-May Sim, Lai-Wah Chan, Wai-Keung Chui*, Synthesis and antimicrobial activity of N1-benzyl or N1 -benzyloxy-1,6-dihydro-1,3,5-triazine-2,4-diamines, Bioorganic & Medicinal Chemistry Letters, 21 (18), 5428-5431, 2011
  5. Xiang Ma,Eric Chun Yong Chan*. On-line Chromatographic Screening of Matrix Metalloproteinase Inhibitors using Immobilized MMP-9 Enzyme Reactor. Journal of Chromatography B, 2010, 878, 1777.
  6. Xiang Ma*, Wai-Keung Chui*. Antifolate and Antiproliferative Activity of 6,8,10-Triazaspiro[4.5]deca-6,8-Dienes and 1,3,5-Triazaspiro[5.5]undeca-1,3-Dienes. Bioorganic and Medicinal Chemistry, 2010, 18, 737-743.
  7. Xiang Ma, Eric Chun Yong Chan*. Fluorescence-Based Liver Microsomal Assay for Screening of Pharmaceutical Reactive Metabolites using Glutathione Conjugated 96-Well Plate. Bioconjugate Chem. 2010, 21 (2), 46-55.
  8. Xiang Ma, Eric Chun Yong Chan*. Fluorescence-based Screening of Pharmaceutical Reactive Metabolites Using Glutathione Immobilized 96-Well Microsomal Assay. Drug Metabol. Rev., 2009; 41(S2): 26.
  9. Xiang Ma*, Renee Ser-Peng Woon, Paul Chi-Lui Ho and Wai-Keung Chui*. Antiproliferative Activity against MCF-7 Breast Cancer Cells by Diamino-Triaza spirodiene Antifolates. Chemical Biology & Drug Design, 2009, 74, 322-326. 
  10. Xiang Ma*, Thong-Yuen Poona, Peter TH Wong and Wai-Keung Chui*. Synthesis and in vitro Evaluation of 2,4-Diamino-1,3,5-Triazines Derivatives as Neuronal Voltage-Gated Sodium Channel Blockers. Bioorganic & Medicinal Chemistry Letters, 2009, 19, 5644-5647. (SCI, IF 2.6)
  11. Ma Xiang*, Zhou Weicheng,* Brun Reto. Synthesis, in vitro antitrypanomal and antibacterial activity of phenoxy, phenylthio or benzyloxy substituted quinolones. Bioorganic & Medicinal Chemistry Letters, 2009, 19, 986-989. 
  12. Hyun-Soon Chong*, Hyun A Song, Xiang Ma, Sooyoun Lim, Xiang Sun and Santosh Mhaske. Bile Q1 acid-based polyaminocarboxylate conjugates as targeted antitumor agents. Chemical Communication, 2009, 21: 3011-3. 
  13. Hyun-Soon Chong*, Xiang Ma, Thien Le, Baidoo Kwame na, Diane E. Milenic, Erik D. Brady, Hyun A. Song, Martin W. Brechbiel. Rational Design and Generation of a Bimodal Bifunctional Ligand for Antibody-Targeted Radiation Cancer Therapy. J. Med. Chem. 2008, 51, 118–125. 
  14. Hyun-Soon Chong*, Xiang Ma, Haisung Lee, Phuong Bui, Hyun A. Song, Noah Birch. Synthesis and Evaluation of Novel Polyaminocarboxylate-Based Antitumor Agents. J. Med. Chem. 2008, 51, 2208–2215. 
  15. Hyun-Soon Chong,*, Hyun A. Song, Xiang Ma, Diane E. Milenic, Erik D. Brady, Sooyoun Lim, Haisung Lee, Kwamena Baidoo, Dengfeng Cheng, Martin W. Brechbiel. Novel Bimodal Bifunctional Ligands for Radioimmunotherapy and Targeted MRI. Bioconjugate Chemistry 2008, 19, 1439-1447. 
  16. Hyun-Soon Chong,* Hyun A. Song, Noah Birch, Thien Le, Sooyoun Lim, Xiang Ma. Efficient synthesis and evaluation of bimodal ligand NETA. Bioorganic & Medicinal Chemistry Letters, 2008, 18, 3436-3439. 
  17. Hyun-Soon Chong,* Hyun A. Song, Sooyoun Lim, Keith Macrenaris, Xiang Ma, Haisung Lee, Phuong Buia and Thomas Meade. A novel cholic acid-based contrast enhancement agent for targeted MRI. Bioorganic & Medicinal Chemistry Letters, 2008, 18, 2505–2508. 
  18. Kong Kah-Hoe, Chen Yu, Ma Xiang, Chui Wai Keung, Lam Yulin*. Traceless solid-phase synthesis of nitrogen-containing heterocycles and their biological evaluations as inhibitors of neuronal sodium channels. Journal of Combinatorial Chemistry, 2004, 6(6), 928-933. 
  19. Ma Xiang; Zhou Weicheng*.  Progress in research on synthetic antibacterial agents oxazolidinones. Zhongguo Yiyao Gongye Zazhi (Chinese Journal of Pharmaceuticals), 2000, 31(8), 370-376.