基本情况

郑世军，免疫学博士，中国农业大学特聘教授、博士生导师，国家杰出青年基金获得者，新世纪百千万人才工程国家级人选，中国农科院教学名师，全国华侨侨眷先进个人，获国务院特殊专家津贴。

 

研究领域

目前主要从事抗感染免疫的分子机理以及畜禽传染病免疫防制的研究

 

教育背景

2000年12月至2005年6月 博士后，美国宾夕法尼亚大学

1996年8月至2000年12月 博士，美国麻省大学

1987年9月至1990年7月 硕士，中国农业大学

1982年9月至1987年7月 学士，中国农业大学

 

工作经历

2005年7月至今 特聘教授，中国农业大学

2000年12月至2005年6月 博士后，美国宾夕法尼亚大学

1996年8月至2000年12月 研究助理，美国麻省大学

1993年1月至1996年8月 讲师，中国农业大学

1990年7月至1993年1月 助教，中国农业大学

 

学术兼职

中国农学会理事会理事

中国免疫学会北京市免疫学分会理事

中国免疫学会动物免疫学分会常务理事


中国畜牧兽医学会动物传染病学分会常务理事

农业生物技术国家重点实验室研究员

全国动物疫病防控专家委员会委员

 

所获荣誉

国家杰出青年基金获得者

新世纪百千万人才工程国家级人选

获国务院特殊专家津贴

中国农科院教学名师

全国华侨侨眷先进个人

 

主要论著

  1. Zhao D, Li J, Wang Y, Li X, Gao L, Cao H, and Zheng SJ*. Critical role for G3BP1 ininfectious bursal disease virus (IBDV)-induced stress granule formation and viral replication. Vet Microbiology 2020, 248: 108806. doi.org/10.1016/j.vetmic.2020.108806.
  2. Li J and Zheng SJ*. Role of microRNAs in host defense against infectious bursal disease virus (IBDV) infection: a hidden front line. Viruses 2020, May 14, 12(543): 1-18. doi:10.3390/v12050543
  3. Duan X, Zhao M, Li X, Gao L, Cao H, Wang Y*, and Zheng SJ*. gga-miR-27b-3p Enhances Type I Interferon Expression and Suppresses Infectious Bursal Disease Virus Replication via Targeting Cellular Suppressors of Cytokine Signaling 3 and 6 (SOCS3 and 6). Virus Research 2020, Feb 29:197910. doi: 10.1016/j.virusres.2020.197910. PMID: 32126296
  4. Duan X, Zhao M, Wang Y, Li X, Cao H, and Zheng SJ*. Epigenetic upregulation of chicken microRNA-16-5p expression in DF-1 cells following infection with Infectious Bursal Disease Virus (IBDV) enhances IBDV-induced apoptosis and viral replication. J Virology 2020, 94（2）. pii: e01724-19. doi: 10.1128/JVI.01724-19
  5. Zhao M, Duan X, Wang Y, Gao L, Cao H, Li X*, and Zheng SJ*. A novel role for PX, a structural Protein of Fowl Adenovirus Serotype 4 (FAdV4), as an Apoptosis-inducer in Leghorn Male Hepatocellular Cells. Viruses 2020, Feb 18;12(2). pii: E228. doi: 10.3390/v12020228
  6. Zhou L and Zheng SJ* The roles of microRNAs(miRNAs) in avian response to viral infection and pathogenesis of avian immunosuppressive diseases. Itnl J of Mol Sci  2019, Nov 1;20(21). pii: E5454. doi: 10.3390/ijms20215454
  7. Gao J, Zhao M, Duan X, Wang Y, Cao H, Li X* and Zheng SJ* Requirement of cellular protein CCT7 for the replication of fowl adenovirus serotype 4 (FAdV-4) in leghorn male hepatocellular cells via interaction with the viral hexon protein. Viruses 2019, 11, 107; doi:10.3390/v11020107
  8. He Z, Chen X, Fu M, Tang J, Li X, Cao H, Wang Y*, and Zheng SJ*.Inhibition of fowl adenovirus serotype 4 replication in Leghorn male hepatoma cells by SP600125 via blocking JNK MAPK pathway. Vet Microbiology 2019, 228: 45-52
  9. Gao J, Duan X, Li XQ, Cao H, Wang Y* and Zheng SJ* Emerging of A Highly Pathogenic and Multi-drug resistant Strain of Escherichia Coli Causing an outbreak of Colibacillosis in Chickens, Infection, Genetics and Evolution 2018, 65: 392-398
  10. Fu M, Wang B, Chen X, He Z, Wang Y, Li X, Cao H, Zheng SJ*. gga-miR-454 suppresses infectious bursal disease virus (IBDV) replication via directly targeting IBDV genomic segment B and cellular Suppressors of Cytokine Signaling 6 (SOCS6). Virus Research 2018, 252: 29-40
  11. Wang B, Fu M, Liu Y, Wang Y, Li X, Cao H, and Zheng SJ* gga-miR-155 Enhances Type I Interferon Expression and Suppresses Infectious Burse Disease Virus Replication via Targeting SOCS1 and TANK. Front Cell Infect Microbiol 2018, 8(55); 1-13
  12. Chen X, He Z, Fu M, Wang Y, Wu H, Li X, Cao H, and Zheng SJ* The E3 ubiquitin ligase Siah-1 suppresses avian reovirus infection by targeting p10 for degradation, J Virology 2018, 92(6). pii: e02101-17
  13. Wang B, Duan X, Fu M, Liu Y, Wang Y, Li X, Cao H, and Zheng SJ* The Association of Ribosomal Protein L18 (RPL18) with IBDV VP3 Enhances Viral Replication, Virus Research 2018, 245:69-79
  14. He Z, Chen X, Fu M, Tang J, Li X, Cao H, Wang Y, and Zheng SJ*. Infectious bursal disease virus protein VP4 suppresses, type I interferon expression via inhibiting K48-linked ubiquitylation of glucocorticoid-induced leucine zipper (GILZ), Immunobiology 2018, 223(4-5):374-382
  15. Fu M, Wang B, Chen X, He Z, Wang Y, Li X, Cao H, and Zheng SJ*, gga-miR-130b suppresses infectious bursal disease virus replication via targeting the viral genome and cellular SOCS5,J Virology 2017, 92(1). pii: e01646-17
  16. Qin Y, Xu Z, Wang Y, Li X, Cao H, and Zheng SJ*, VP2 of Infectious Bursal Disease Virus induces apoptosis via triggering Oral Cancer Overexpressed 1 (ORAOV1) protein degradation. Front Microbiology 2017, July, 8(1): doi: 10.3389/fmicb.2017.01351
  17. Li X, Liu Y, Wang Y, Liu J, Li XQ, Cao H, Gao X and Zheng SJ*, Negative regulation of hepatic inflammation by the Soluble Resistance-Related Calcium Binding Protein via STAT3. Front Immunology 2017, 8: 1-14
  18. Qin Y and Zheng SJ* .Infectious Bursal Disease Virus-Host Interactions: Multifunctional Viral Proteins that Perform Multiple and Differing Jobs. Itnl J of Mol Sci 2017, 18, 161; doi:10.3390/ijms18010161
  19. Xu Z, Qin Y, Wang Y, Li X,Cao H, and Zheng SJ*,  A Critical role of bacterioferritin in Salmonella pullorum-induced IFN-β expression in DF-1 cells, Front Microbiology 2016, 7(1): doi: 10.3389/fmicb.2016.00020
  20. Wu H, H Z, Tang J, Li X,Cao H, Wang Y*, and Zheng SJ* A critical role of LAMP-1 inavian reovirus P10 degradation associated with inhibition of apoptosis and virus release. Arch Virol 2016, 161:899–911
  21. Lin W, Zhang Z, Xu Z, Wang B, Wang Y, Li XQ, Cao H, and Zheng SJ*. The Association of Receptor of Activated Protein Kinase C 1(RACK1) with Infectious Bursal Disease Virus Protein VP5 and VDAC2 Inhibits Apoptosis and Enhances Viral Replication. J Biol Chem. 2015, 290(13): 8500-10
  22. Zhang Z, Lin W, Wu H, Wang Y, Li XQ, Cao H, and Zheng SJ*, Critical Roles of Eukaryotic Elongation Factor 1 alpha(eEF1A1)in Avian Reovirus Sigma C-induced Apoptosis and Inhibition of Viral Growth. Archives of Virology 2015, 160:1449–1461
  23. Zheng W, Li X, Wang J, Li XQ, Cao H, Wang Y, Zeng Q, and Zheng SJ*. A critical role of interferon-induced protein IFP35 inFoot-and-Mouth Disease Virus(FMDV) protein2C-induced type I interferon response in cells. Archives of Virology 2014, 159(11):2925-35
  24. Li X, Wang J, Liu J, Li Z, Wang Y, Xue Y, and Zheng SJ*. Engagement of Soluble Resistance-Related Calcium Binding Protein (sorcin) with foot-and-mouth disease virus (FMDV) VP1 inhibits type I interferon response in cells, Vet Microbiology 2013,166: 35–46
  25. Li Z, Wang Y, Li X, Li XQ, Cao H, and Zheng SJ*. Critical Roles of Glucocorticoid-Induced Leucine Zipper in Infectious Bursal Disease Virus (IBDV)-induced Suppression of Type I Interferon Expression and Enhancement of IBDV Growth in Host Cells via Interaction with VP4. J Virology 2013, 87(2):1221-1231
  26. Li X, Li XQ, Cao H, Wang Y, and Zheng SJ*. Engagement of new castle disease virus (NDV) matrix (M) protein with charged multivesicular body protein (CHMP) 4 facilitates viral replication. Virus Research 2013, 171: 80-88
  27. Wang J, Wang Y, Liu J, Ding L, Zhang Q, Li X, Cao H, Tang J, and Zheng SJ*. A critical role of N-myc and STAT interactor (Nmi) in foot-and-mouth disease virus (FMDV)2C-induced apoptosis. Virus Research 2012, 170 (2012) 59– 65
  28. Luo Z, Li Z, Chen K, Liu R, Li X, Cao H, and Zheng SJ*. Engagement of Heterogeneous Nuclear Ribonucleoprotein M with Listeriolysin O Induces Type I Interferon Expression and Restricts Listeria Monocytogenes Growth in Host Cells. Immunobiology 2012, 217(10): 972-981
  29. Li Z, Wang Y, Xue Y, Li X, Cao H, and Zheng SJ*. A critical role for voltage-dependent anion channel (VDAC)2 ininfectious bursal disease virus (IBDV)-induced apoptosis in host cells via interacting with VP5. J Virology 2012, 86(3): 1328-1338
  30. Ruan W, Wu Y, Zheng SJ*. Different genetic patterns in avian Toll-like receptor (TLR)5 genes. Mol Biol Rep. 2012,39(4)3419-26
  31. Ruan WK, Wu YH, An J, Cui DF, Li HR, Zheng SJ*. Toll-like receptor 2 type 1 and type 2 polymorphisms in different chicken breeds. Poultry Science. 2012, Jan; 91(1):101-6
  32. Ruan Q, Kameswaran V, Zhang Y, Zheng S, Sun J, Wang J, Devirgiliis J, Liou HC, Beg AA, Chen YH. The Th17 immune response is controlled by the Rel-ROR{gamma}-ROR{gamma}T transcriptional axis. J Exp Med. 2011 Oct 24; 208 (11):2321-33
  33. Ruan WK, Zheng SJ*. Polymorphisms of chicken toll-like receptor 1 type 1 and type2 indifferent breeds. Poultry Science 2011, Sep; 90(9):1941-7
  34. Li H, Li X, Lu Y, Wang X, Zheng SJ*. Staphylococcus sciuri exfoliative toxin C is a dimer that modulates macrophage functions. Can. J. of Microbiology 2011, 57: 722-729
  35. Li H, Wang Y, Ding L, and Zheng SJ*. Staphylococcus sciuri exfoliative toxin C (ExhC) is a necrosis-inducer for mammalian cells. PLoS ONE 2011, 6 (7): e23145: 1-9
  36. Li H, He F, Zhang Z, Zheng SJ*. Critical roles of amino acids Ser231, His107 and Asp156 of Staphylococcus sciuri exfoliative toxin C (ExhC) in the induction of skin exfoliations of neonate. Biologia 2011: 90-11C
  37. Chen K, Luo Z, Tang J, Zheng SJ*. A critical role of heat shock cognate protein70 inApoptin-induced phosphorylation of Akt. Biochem Biophys Res Commun. 2011 Jun 3; 409(2):200-4
  38. Chen K, Luo Z, Zheng SJ*. Gallus Heat shock cognate protein 70, a novel binding partner of Apoptin. Virol J. 2011 Jun 27; 8: 324-333
  39. 付梦娇，王永强，李晓齐，曹红，陈福勇，郑世军*，一株传染性法氏囊病毒野毒株的分离与鉴定，亚洲兽医病例研究，2016，5(1), 5-10
  40. 甘孟侯、郑世军《中国猪病学/甘孟侯、杨汉春主编》第九章：猪传染病的发生、发展及流行，123-133页，2005年8月，中国农业出版社
  41. 甘孟侯、郑世军、李文刚《养鸡500天-第五版/甘孟侯主编》第八部分：疫病防治，121-231页，2007年1月，中国农业出版社
  42. 郑世军（参编）《新编人兽共患病学》（金宁一等主编），1050-1082页，2007年9月，中国科技出版社
  43. 郑世军参编《畜禽群发病防治》第三版（甘孟侯蒋金书主编）第一章：畜禽传染病流行规律和防控措施，3-18页，2009年10月，中国农业大学出版社
  44. 郑世军参编《抗病毒天然免疫》（舒红兵主编），第一章：天然免疫简介，1-11页，2009年9月，科学出版社
  45. 郑世军、宋清明主编《现代动物传染病学》郑世军撰写（1-13页；177-197页）、2013年12月，中国农业大学出版社（获国家出版基金项目资助）
  46. 甘孟侯主编，郑世军、郎震美副主编《养鸡500天-第六版》第八部分：疫病防治，138-237页，2014年1月，中国农业出版社
  47. 郑世军著《动物分子免疫学》2015年，2015年9月，中国农业大学出版社
  48. Zheng SJ, contributor to the IBDV chapter for the Book “Avian Virology-Current Research and Future Trends” by Caister Academic Press, Sept. 2019
  49. 郑世军著《动物分子免疫学-第二版》2020年，2021年6月出版，中国农业大学出版社