基本情况
吴佳妍，中科院北京基因组研究所副研究员，硕士生导师。在国际SCI期刊上发表论文40多篇，专著1部，获批专利2项。主持完成国家973计划、863计划、国家科技支撑计划子课题，承担国家自然科学基金、教育部留学回国人员科研启动基金等多项课题。
研究领域
对基因组学、转录组学和表观遗传组学数据进行深度挖掘，进行以精准医疗为目的的个人基因组研究；延续现有原核生物泛基因组学研究成果，进行广泛的比较基因组学研究；发展和改进高通量测序数据深度挖掘分析方法，进行算法，并构建相应的数据库
教育背景
2006年 博士后，美国Emory大学
2005年 博士，吉林大学
2000年 学士，沈阳化工学院
论文发表
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吴佳妍，基因组学核心实验方法（4-6章）。科学出版社（2012）
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Meili Chen, Jingfa Xiao, Jingxing Liu, Zhang Zhang, Jiayan Wu*, Jun Yu*,
Identification of Human HK Genes and Gene Expression Regulation Study in Cancer
from Transcriptomics.PLoS ONE, 8, e54082 (2013)
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Jiayan Wu,Jingfa Xiao, Jun Yu. Latest notable achievements in genomics. Science
in China, 55, 645-648 (2012)
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Yan Ge*, Jiayan Wu,* Ming Yang, Yingjie Xia, Jingfa Xiao, Jun Yu, Molecular
Dynamics Simulation of the Complex PBP-2x with Drug Cefuroxime to Explore the
Drug Resistance Mechanism of Streptococcus suis R61. PLoS ONE, 6, e35941 (2012)
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Dongyu Zhao*, Jiayan Wu*, Wei Gong, Yuanyuan Zhou, Jing Jin, Jingfa Xiao, Jun
Yu, WikiCell: a unified resource platform for human transcriptomics research.
OMICS: A Journal of Integrative Biology, 16 (6) 357-362 (2012)
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Yongbing Zhao*, Jiayan Wu*, Junhui Yang, Shixiang Sun, Jingfa Xiao, Jun Yu,
PGAP: Pan-Genomes Analysis Pipeline. Bioinformatics, 28, 416-418 (2012)
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Jingde Bu*, Jiayan Wu*,Meili Chen, Jingfa Xiao, Jun Yu, Xuebin Chi, Zhong Jin,
BAsplice: Bi-direction Alignment for detecting splice junctions. IEEE ISB 2012,
Xi’an, China, 253-256 (2012)
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Zaichao Zhang†, Jiayan Wu†, Jun
Yu, Jingfa Xiao. A brief review on the evolution of GPCR: conservation and
diversification. Open Journal of Genetics, 2, 11-17 (2012)
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Zhang Zhang, Jingfa Xiao, Jiayan Wu, Haiyan Zhang, Guiming Liu, Xumin Wang, Lin
Dai, ParaAT: a parallel tool for constructing multiple protein-coding DNA
alignments. Biochemical and Biophysical Research Communications, 419, 779-781
(2012)
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Yan Ge*, Jiayan Wu,*Jingfa Xiao, Jun Yu, Exploration of the binding mode of α/β-type small acid soluble proteins (SASPs)
with DNA. Journal of Molecular Modeling, Vol. 17, 3183-3193 (2011)
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Jiayan Wu†,Jingfa Xiao†, Ruosi
Zhang, Jun Yu.DNA sequencing leads to genomics progress in China. Science in
China, 54, 290-292 (2011)
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Zunming Liu, Jingfa Xiao, Jiayan Wu*, Jun Yu*, RNADAP-RNA-Seq Data Annotation
Pipeline. IEEE ISB 2011, Zhuhai, China, 84-86 (2011)
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Ming Yang, Yan Ge, Jiayan Wu, Jingfa Xiao, Jun Yu, Coevolution study of
mitochondria respiratory chain proteins: Toward the understanding of
protein-protein interaction. Journal of Genetics and Genomics, Vol. 38, 201-207
(2011)
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Pan Hu, Ming Yang, Anding Zhang, Jiayan Wu, Bo Chen, Yafeng Hua, Jun Yu,
Huanchun Chen, Jingfa Xiao, Meilin Jin, Comparative Genomics Study of
Multi-Drug-Resistance Mechanisms in the Antibiotic-Resistant Stretococcussuis
R61 Strain. PLOS one. 6, e24988 (2011)
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Anding Zhang, Ming Yang, Pan Hu, Jiayan Wu, Bo Chen, YafengHua, Jun Yu,
Huanchun Chen, Jingfa Xiao and Meilin Jin, Comparative Genomic Analysis of
Stretococcussuis reveals significant genomic diversity among different
serotypes. BMC Genomics, Vol. 12, 523 (2011)
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Pan Hu, Ming Yang, Anding Zhang, Jiayan Wu, Bo Chen, YafengHua, Jun Yu, Jingfa
Xiao, Meilin Jin, Complete Genome Sequence of Stretococcussuis serotype 14
Strain JS14. Journal of Bacteriology, Vol.193, No.9, 2375-2376 (2011)
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Zongjun Du, Zhewen Zhang, Tingting Miao, Jiayan Wu,GuoqiangLü, Jun Yu, Jingfa Xiao, and Guanjun Chen, Draft Genome Sequence of
the Novel Agar-Digesting Marine Bacterium HQM9. Journal of Bacteriology, Vol.
193, No. 17, 4557-4558 (2011)
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Pan Hu, Ming Yang, Anding Zhang, Jiayan Wu, Bo Chen, YafengHua, Jun Yu,
Huanchun Chen, Jingfa Xiao, Meilin Jin, Complete Genome Sequence of
StretococcussuisSerotype 3 strain ST3. Journal of Bacteriology, Vol. 193,
No.13, 3428-3429 (2011)
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Wenming Zhao, Wanfei Liu, DongmeiTian, Bixia Tang, Yanqing Wang, Caixia Yu,
Rujiao Li, Yunchao Ling, Jiayan Wu, Shuhui Song, Songnian Hu, wapRNA: a
web-based application for the processing of RNA sequences, Bioinformatics, Vol.
27(21)
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吴佳妍，肖景发，张若思，于军，DNA测序技术引领中国基因组科学走向未来，中国科学：生命科学，第40卷，第12期：1169-1172，（2010）
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Jiang Zhu, Fuhong He, Dapeng Wang, Kan Liu, Dawei Huang, Jingfa Xiao, Jiayan
Wu, Songnian Hu, Jun Yu. A Novel Role for Minimal Introns: Routing mRNAs to the
Cytosol. PLOS one. 5, e10144 (2010)
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Ewan Birney, Thomas J Hudson, Eric D Green, …,Jiayan
Wu, Jun Yu, Prepublication data sharing. Nature, 461(7261), 168-170 (2009)