Personal Information
Wei Yan
Postdoctoral Research Fellow of Johns Hopkins University School of Medicine
Research Interests
Stem cell and gene targeting
Publications
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Yan W, Zhang, H., Wu, M., Inoue, T. and Li, M. Monitoring iodide ion flux through TMEM16a with a new split TEV protease (to be submitted in Feb 2013)
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Zhang H, Zou B, Yu H, Moretti A, Wang X, Yan W, Babcock JJ, Bellin M, McManus OB, Tomaselli G, Nan F,Laugwitz KL and Li M (2012) Modulation of hERG potassium channel gating normalizes action potential duration prolonged by dysfunctional KCNQ1 potassium channel, Proc. Natl. Acad. Sci. USA 109, 11866-11871
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Imanishi M, Imamura C, Higashi C, Yan W, Negi S, Futaki S and Sugiura Y (2010) Zinc finger-zinc finger interaction between the transcription factors, GATA-1 and Sp1, Biochem. Biophys. Res. Commun. 400, 625-630
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Jia H, Liu Y, Yan W and Jia J (2009) PP4 and PP2A regulate Hedgehog signaling by controlling Smo and Ci phosphorylation, Development 136, 307-316
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Yan W, Imanishi M, Futaki S and Sugiura Y (2007) α-helical linker of an artificial 6-zinc finger peptide contributes to selective DNA binding to a discontinuous recognition sequence, Biochemistry 46, 8517-8524
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Imanishi M, Yan W, Morisaki T and Sugiura Y (2005) An artificial six-zinc finger peptide with polyarginine linker: selective binding to the discontinuous DNA sequences, Biochem. Biophys. Res. Commun. 333, 167-173
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Yan W and Cheng L, Correction of the sickle mutation in human iPS cells using TALEN designer nuclease (poster presentation at 5th Annual Meeting of Maryland Stem Cell Research Symposium in Oct 4-5 2012 at Maryland, USA)
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Zou B, Yu H, Zhang H, Yan W and Li M, Proteins and heart-when vast chemical diversity meets human cells (poster presentation at 4th Annual Meeting of Maryland Stem Cell Research Symposium in Oct 4-5 2012 at Maryland, USA)
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Yan W, Imanishi M, Futaki S and Sugiura Y, The effect of the α-helical linker in an artificial 6-zinc finger peptide on DNA binding (poster presentation at 2nd Annual Meeting of Japanese Society for Chemical Biology in May 9-10 2007 at Kyoto, Japan)
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Yan W, Imanishi M, Futaki S and Sugiura Y, The DNA binding of an artificial 6-zinc finger peptide with α helical linker (oral presentation at 127th Annual meeting of the Pharmaceutical Society of Japan in Mar 28-30 2007 at Toyama, Japan)
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Yan W, Imanishi M and Futaki S, The distinction of the target DNA phases by an novel 6-zinc finger peptide with α helical linker (poster presentation at 106th Presentation Meeting of Institute for Chemical Research, Kyoto University in Dec 15 2006 at Uji, Japan)
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Yan W, Imanishi M, Morisaki T and Sugiura Y, The high selectivity of a novel 6-zinc finger peptide with polyarginine linker (oral presentation at 8th Annual Meeting for Kansai Chinese Association of Life Science in Nov 5 2006 at Nara, Japan)
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Imanishi M, Yan W, Futaki S and Sugiura Y, DNA binding properties of multi-zinc finger peptides with artificial linkers (poster presentation at 126th Annual meeting of the Pharmaceutical Society of Japan in Mar 27-30 2006 at Sendai, Japan)
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Imanishi M, Yan W, Futaki S and Sugiura Y, The DNA binding of zinc finger peptides with various linker(poster presentation at 4th SORST Joint Symposium in Nov 28-29 2005 at Suita, Japan)
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Yan W, Imanishi M, Morisaki T and Sugiura Y, Increase in DNA binding selectivity by introducing polyarginine as the linker of a 6-zinc finger peptide (oral presentation at The International Symposium of Chinese Academy of Science and Engineering in Japan in Oct 29-30 2005 at Fujihakone, Japan)
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Imanishi M, Yan W, Morisaki T, Futaki S and Sugiura Y, Selective binding to the discontinuous DNA sequences by an artificial zinc finger peptide with polyarginine linker (poster presentation at Metalloprotein and Protein Design Conference in Jul 28-30 2005 at Chicago, USA)
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Yan W, Imanishi M, Morisaki T and Sugiura Y, Increase in DNA binding selectivity by introducing polyarginine as the linker of a 6-zinc finger peptide (poster presentation at 4th International Symposium of the Kyoto COE Project “Elements Science” in Jan 6-7 2005 at Kyoto, Japan)
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Yan W, Imanishi M and Sugiura Y, The DNA binding selectivity of an artificial 6-zinc finger peptide with arginine linker (oral presentation at 54th General Meeting of the Kinki Branch of the Pharmaceutical Society of Japan in Oct 23 2004 at Kobe, Japan)
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Imanishi M, Yan W and Sugiura Y, The investigation about the DNA binding selectivity of an artificial 6-zinc finger peptide (poster presentation at 14th Symposium on Roles of Metals in Biological Reaction, Biology and Medicine in Jun 10-11 2004 at Shizuoka, Japan)
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Yan W, Imanishi M and Sugiura Y, The DNA binding selectivity of an artificial 6-zinc finger peptide with arginine linker (poster presentation at 124th Annual meeting of the Pharmaceutical Society of Japan in Mar 29-31 2004 at Osaka, Japan)