基本情况

叶明，博士，先后于合肥工业大学任教授（4级至2级）、硕士生导师、博士生导师、系主任、安徽省教学名师。先后主持国家及省部级纵向项目20余项、横向项目10余项，主持省、校级教学质量工程项目10余项，以第一（或通讯）作者在国内外核心期刊发表论文120余篇，其中SCI收录40余篇，以第一发明人申报国家发明专利近40项，其中30多项已经获得授权（部分在实审中）；培养硕士研究生、博士研究生（境外2名）、博士后50余名。安徽省微生物学精品课程建设项目负责人，安徽省微生物学会常务理事，安徽省食用菌学会理事，安徽省食品质量安全委员会委员。《微生物学杂志》编委，《生物学杂志》编委，《微生物前沿》编委，《食品研究与开发》编委。先后参加国家科技部863项目、国家科技进步奖项目、教育部高等学校优秀科技成果奖、国家自然科学基金项目、国家精品课程项目评审。

 

研究领域

1. 微生物源活性物质结构、功能及其作用机理

2. 新型功能食品研制及其功能评价

3. 食品生物技术及特色农产品精深加工

 

科研项目

  1. 国家自然科学基金面上项目：粒毛盘菌属多糖结构、分子修饰与生物活性研究.(31470146，主持）
  2. 安徽省科研计划重大专项项目：植源型功能发酵乳加工关键技术研究及其产业化（15czz03106，主持）
  3. 国家自然科学基金面上项目：粒毛盘菌属黑色素活性筛选、分子修饰及构效关系研究.(31270060，主持)
  4. 科技部企业创新项目：高产粒毛盘菌菌株选育与水溶性活性黑色素产品.(12C26213403307，主持)
  5. 中央高校基本科研业务费专项资金项目：粒毛盘菌降脂、抗衰老多糖胶囊关键技术研究.( 2012HGZY0020，主持)
  6. 安徽省科技攻关重点项目：瓜蒌深加工关键技术研发及新产品研发. (12010302071，主持)
  7. 国家自然科学基金面上项目：华东地区粒毛盘菌资源与活性物质研究（31070021，主持）
  8. 企业委托项目：宣酒酿造微生物菌群改良、发酵工艺及其保健功能成分研究（W2016JSKF0081主持）
  9. 企业委托项目：坚果保藏及深加工关键技术研究 （W2017JSKF0044，主持）
  10. 企业委托项目：山核桃新产品研发及其保质期研究（W2014JSKF0229，主持）

 

部分专著

叶明主编，安徽省“十一五”规划教材《微生物学》（化学工业出版社 2010年版）

叶明主编，安徽省“十一五”规划教材《微生物实验技术》（合肥工业大学出版社 2009年版）

 

论文发表

  1. Hou GH, Chen X, Li JL, Ye ZY, Zong S, Ye M*. Physicochemical properties, immunostimulatory activity of the Lachnum polysaccharide and polysaccharide-dipeptide conjugates. Carbohydrate Polymers, 2019, 206: 446-454.
  2. Zhang WQ, Si GR, Li JL, Ye M*, Feng SS, Mei J, Yang QH, Wang JS, Zhou P. Tetramethylpyrazine in Chinese sesame flavour liquor and changes during the production process. Journal of the Institute of Brewing, 2019, 125(1): 155-161.
  3. Hou GH, Surhio MM, Ye HL, Gao XM, Ye ZY, Li JL, Ye M*. Protective effects of a Lachnum polysaccharide against liver and kidney injury induced by lead exposure in mice. International Journal of Biological Macromolecules, 2019, 124: 716-723.
  4. Shi F, Li JL, Yang LQ, Hou GH, Ye M*. Hypolipidemic effect and protection ability of liver-kidney functions of melanin from Lachnum YM226 in high-fat diet fed mice. Food & Function, 2018, 9(2): 880-889.
  5. Shi F, Li JL, Ye ZY, Yang LQ, Chen TT, Chen X, Ye M*. Antitumor effects of melanin from Lachnum YM226 and its derivative in H22 tumor-bearing mice. MedChemComm, 2018, 9(6): 1059-1068.
  6. Su NN, Li JL, Yang LQ, Hou GH, Ye M*. Hypoglycemic and hypolipidemic effects of fermented milks with added roselle ( Hibiscus sabdariffa, L.) extract. Journal of Functional Foods, 2018, 43: 234-241.
  7. Su NN, Li JL, Ye ZY, Chen TT, Ye M*. Quality properties, flavor and hypoglycemia activity of, Kiwifruit-Bitter gourd, fermented milks. Food Bioscience, 2018, 22: 139-145.
  8. Xu P, Yuan RY, Hou GH, Li JL, Ye M*. Structural Characterization and In Vitro Antitumor Activity of a Novel Exopolysaccharide from Lachnum YM130. Applied Biochemistry and Biotechnology, 2018, 185: 541-554.
  9. Wang YF, Hou GH, Li JL, Surhio MM, Ye M*. Structure characterization, modification through carboxymethylation and sulfation, and in vitro antioxidant and hypoglycemic activities of a polysaccharide from Lachnum sp. Process Biochemistry, 2018, 72: 177-187.
  10. Ye ZY, Lu Y, Zong S, Yang LQ, Shaikh F, Li JL, Ye M*. Structure, molecular modification and anti-tumor activity of melanin from Lachnum singerianum. Process Biochemistry, 2018, DOI: https://doi.org/10.1016/j.procbio.2018.09.007.
  11. Li SL, Yang LQ, Li JL, Chen TT, Ye M*. Structure, Molecular Modification, and Anti-radiation Activity of Melanin from Lachnum YM156 on Ultraviolet B-Induced Injury in Mice. Applied Biochemistry and Biotechnology, 2018(4): 1-13.
  12. Zong S, Li JL, Yang L, Huang QL, Hou GH, Ye M*. Synergistic antitumor effect of polysaccharide from, Lachnum sp. in combination with cyclophosphamide in hepatocellular carcinoma. Carbohydrate Polymers, 2018, 196: 33-46.
  13. Fang Shi, Jinglei Li, Liuqing Yang, Guohua Hou and Ming Ye*. Hypolipidemic effect and protection ability of liver-kidney functions of melanin from Lachnum YM226 in high-fat diet fed mice. Food & Function, 2018. DOI: 10.1039/C7FO01294B. (SCI)
  14. Maheen Mahwish Surhio, Yufen Wang, Ping Xu, Shah Faisal, Jinglei Li, Ming Ye*. Antihyperlipidemic and hepatoprotective properties of selenium modified polysaccharide from Lachnum, sp. International Journal of Biological Macromolecules, 2017, 99: 88–95. (SCI)
  15. Tianle Chen, Ping Xu, Shuai Zong, Yufen Wang, Nana Su, Ming Ye*. Purification, structural features, antioxidant and moisture-preserving activities of an exopolysaccharide from Lachnum YM262. Bioorganic & Medicinal Chemistry Letters, 2017, 27: 1225–1232. (SCI)
  16. Lan Li, Fang Shi, Jinglei Li, Qianli Huang, Can Xu, Liuqing Yang, Qinghua Yang, Farnaz Shaikh, Ming Ye*. Immunoregulatory effect assessment of a novel melanin and its carboxymethyl derivative. Bioorganic & Medicinal Chemistry Letters, 2017, 27(8): 1831-1834. (SCI)
  17. Shenglan Li, Jinglei Li, Fang Shi, Liuqing Yang and Ming Ye*. Protection effect of intracellular melanin from Lachnum YM156 and Haikunshenxi capsule combination on adenine-induced chronic renal failure in mice, MedChemComm, 2017, 8(5): 917-923. (SCI)
  18. Yufen Wang, Nana Su, Guohua Hou, Jinglei Li and Ming Ye*. Hypoglycemic and hypolipidemic effects of a polysaccharide from Lachnum YM240 and its derivatives in mice induced by high fat diet and low dose STZ. Medchemcomm, 2017, 8: 964-974. (SCI)
  19. Can Xu, Jinglei Li, Liuqing Yang, Fang Shi, Liu Yang, Ming Ye*. Antibacterial activity and a membrane damage mechanism of Lachnum YM30 melanin against Vibrio parahaemolyticus and Staphylococcus aureus, Food Control, 2017, 73: 1445-1451. (SCI)
  20. Ping Xu, Jinglei Li, Guohua Hou, Fang Shi, Ming Ye*. Cardioprotective effect of an exopolysaccharide from Lachnum YM130 and its derivatives on diabetic mice. Process Biochemistry, 2017, 58, 333-340. (SCI)
  21. Min Zhang, Nana Su, Qianli Huang, Qiang Zhang, Yufen Wang, Jinglei Li, Ming Ye*. Phosphorylation and antiaging activity of polysaccharide from Trichosanthes peel. Journal of Food and Drug Analysis, 2017, 25(4): 976-983. (SCI)
  22. Lianyan Jing, Shuai Zong, Jinglei Li, Ming Ye*, Maheen Surahio, Liu Yang. Potential mechanism of protection effect of exopolysaccharide from Lachnum YM406 and its derivatives on carbon tetrachloride-induced acute liver injury in mice. Journal of Functional Foods, 2017, 36: 203–214. (SCI)
  23. Wenqing Zhang, Guanru Si, Ming Ye*, Shoushuai Feng, Fan Cheng, Jinglei Li, Jie Mei, Shuai Zong, Jiasheng Wang, Ping Zhou. An Efficient Assay for Simultaneous Quantification of Ethyl Carbamate and Phthalate Esters in Chinese Liquor by Gas Chromatography-Mass Spectrometry. Food Analytical Methods, 2017, 10, 3487–3495. (SCI)
  24. Maheen Mahwish Surhio, Yufen Wang, Shi Fang, Jinglei Li, MingYe*. Anti-fatigue activity of a Lachnum polysaccharide and its carboxymethylated derivative in mice. Bioorganic & Medicinal Chemistry Letters, 2017, 27, 4777–4780. (SCI)
  25. Sheng Song, Liu Yang, Ming Ye*, Xue Chen, Fang Shi, Farnaz Shaikh. Antioxidant activity of a Lachnum YM226 melanin–iron complex and its influence on cytokine production in mice with iron deficiency anemia. Food & Function, 2016, 7(3): 1508-1514. (SCI)
  26. Sheng Song, Shenglan Li, Nana Su, Jinglei Li, Fang Shi and Ming Ye*. Structural characterization, molecular modification and hepatoprotective effect of melanin from Lachnum YM226 on acute alcohol-induced liver injury in mice. Food & Function, 2016, 7(8): 3617-3627. (SCI)
  27. Tianle Chen, Min Zhang , Jinglei Li, Maheen Mahwish Surhio, Beibei Li, Ming Ye*. Structural characterization and hypoglycemic activity of Trichosanthes peel polysaccharide. LWT-Food Science and Technology, 2016, 70: 55-62. (SCI)
  28. Tianle Chen, Yufen Wang, Jinglei Li, Nana Su, Maheen Mahwish Surhio, Liu Yang, Ming Ye*. Phthaloyl modification of a polysaccharide from Lachnum YM262 and immunomodulatory activity. Process Biochemistry, 2016, 51(10), 1599-1609. (SCI)
  29. Zhanzhan Du, Shuai Zong, Maheen Mahwish Surhio, Ping Xu, Liu Yang, Ming Ye*. Structural characterization and anti-hypoxia activity of an exopolysaccharide isolated from fermentation broth of Lachnum sp. Process Biochemistry, 2016, 51, 1290–1298. (SCI)
  30. Lianyan Jing, Shuai Zong, Jinglei Li, Maheen Mahwish Surhio, Ming Ye*. Purification, structural features and inhibition activity on α-glucosidase of a novel polysaccharide from Lachnum YM406. Process Biochemistry, 2016, 51(10): 1706-1713. (SCI)
  31. Ping Xu, Liu Yang, Ruyue Yuan, Ziyang Ye, Huiran Ye, Ming Ye*. Structure and preventive effects against ethanol-induced gastric ulcer of an expolysaccharide from Lachnum sp. International Journal of Biological Macromolecules, 2016, 86: 10-17. (SCI)
  32. Rong Zhang, Liu Yang, Jing Ji, Bei-bei Li, Lan Li, Ming Ye*. Physicochemical properties and hypoglycaemic activity of fermented milks prepared with Anemarrhena asphodeloides water extracts. Journal of the Science of Food and Agriculture, 2016, 96(2): 492-496. (SCI)
  33. Zhanzhan Du, Fang Shi, Dong Liu, Hongling Ye, Maheen Mahwish Surhio, Jinglei Li, Ming Ye*. Anticoagulant activity of a sulfated Lachnum polysaccharide in mice with a state of hypercoagulability. Bioorganic & Medicinal Chemistry Letters, 2016, 26: 550–5556. (SCI)
  34. Yunlong He, Ming Ye*, Lianyan Jing, Zhanzhan Du, Maheen Surahio, Hongmei Xu, Jie Li. Preparation, characterization and bioactivities of derivatives of an exopolysaccharide from Lachnum. Carbohydrate Polymers, 2015, 117: 788–796. (SCI)
  35. Yanna Wu, Ming Ye*, Zhanzhan Du, Lianyan Jing, Maheen Surahio, Liu Yang. Carboxymethylation of an exopolysaccharide from Lachnum and effect of its derivatives on experimental chronic renal failure. Carbohydrate Polymers, 2014, 114:190-195. (SCI)
  36. Yunlong He, Ming Ye*, Zhanzhan Du, Huiyan Wang, Yanna Wu, Liu Yang. Purification, characterization and promoting effect on wound healing of an exopolysaccharide from Lachnum YM405. Carbohydrate Polymers, 2014, 105: 169-176. (SCI)
  37. Ming Ye*, Geng-yi Guo, Ying Lu, Sheng Song, Hui-yan Wang, Liu Yang. Purification, structure and anti-radiation activity of melanin from Lachnum YM404. International Journal of Biological Macromolecules, 2014, 63: 170-176. (SCI)
  38. Ming Ye*, Geng-yi Guo, Ying Lu, Sheng Song, Hui-yan Wang, Liu Yang. Purification, structure and anti-radiation activity of melanin from fungus Lachnum YM404. International Journal of Biological Macromolecules, 2014, 63: 170–176. (SCI)
  39. Ming Ye*, Li Ren, Yanna Wu, Yan Wang, Yong Liu. Quality characteristics and antioxidant activity of hickory-black soybean yogurt. LWT - Food Science and Technology, 2013, 51: 314-318. (SCI)
  40. Ming Ye*, Zhanzhan Du, Xiaojing Ma. Phosphorylation and anti-tumor activity of expopolysaccharide from Lachnum YM120. Carbohydrate Polymers, 2013, 97(2): 690-694. (SCI)
  41. Tao Qiu, Xiaojing Ma, Ming Ye*, Yanna Wu. Purification, structure, lipid lowering and liver protecting effects of polysaccharide from Lachnum YM281. Carbohydrate Polymers, 2013, 98(1): 922-930. (SCI)
  42. Ming Ye*, Dong Liu, Rong Zhang, Liu Yang, Jing Wang. Effect of hawk tea (Litsea coreana L.) on the numbers of lactic acid bacteria and flavour compounds of yoghurt. International Dairy Journal, 2012, 23: 68-71. (SCI)
  43. Ming Ye*, Wu-xi Chen, Tao Qiu, Ru-yue Yuan, Ying-wang Ye, Jing-min Cai. Structural characterization and anti-aging activity of extracellular polysaccharide from a strain of Lachnum sp. Food Chemistry, 2012, 132: 338–343. (SCI)
  44. Ming Ye*, Yan Wang, Geng-yi Guo, Yun-long He, Ying Lu, Ying-wang Ye, Qing-hua Yang, Pei-zhou Yang. Physicochemical characteristics and antioxidant activity of arginine-modified melanin from Lachnum YM-346. Food Chemistry, 2012, 135: 2490–2497. (SCI)
  45. Ming Ye*, Tao Qiu, Wei Peng, Wu-xi Chen, and Ying-wang Ye, Ying-ren Lin. Purification, characterization and hypoglycemic activity of extracellular polysaccharides from Lachnum calyculiforme. Carbohydrate Polymers, 2011, 86: 285–290. (SCI)

 

专利

  1. 一种水溶性粒毛盘菌黑色素及其作为促排铅药物的用途(2014103063017，2017年授权)
  2. 一种磷酸酯化瓜蒌皮多糖及其医药用途(201510030199.7，2017年授权)
  3. 一种硫酸酯化粒毛盘菌胞外多糖及其在抗凝血医药方面的用途（201510418916.3，2017年授权）
  4. 水溶性粒毛盘菌黑色素在制备抑制肝癌药物中的用途（L201410022755.1，2016年授权）
  5. 一种瓜蒌米乳复合发酵乳饮料的制备方法（ZL201310258166.9，2015年授权）
  6. 瓜蒌皮发酵乳饮料及其制备方法（ZL 201310516111.3，2015年授权）
  7. 一种瓜蒌饮料及其制备方法（ZL201210544013.6，2015年授权）
  8. 复合中草药乳酸菌发酵饮料及其制备方法（ZL201310214814.0，2014年授权）
  9. 以粒毛盘菌胞外多糖作为制备预防胃溃疡药的应用（ZL201210443889.1，2014年授权）
  10. 一种自银杏叶中提取高黄酮含量活性物质的方法（ZL2011101817 94.5，2013年授权）
  11. 粒毛盘菌胞外多糖的降脂利肝用途(ZL20110184104.9，2013年授权)
  12. 一种富锌酸奶发酵剂及富锌酸奶的制备方法（ZL201010231602.X，2013年授权）
  13. 一种将粒毛盘菌胞外黑色素改性为水溶性黑色素的方法（ZL201210218401.5，2013年授权）一种粒毛盘菌多糖新的医药用途（ZL201010582408.6，2012年授权）
  14. 一种粒毛盘菌胞外多糖单一组分的制备方法（ZL200910144922.9，2012年授权）
  15. 一种利用泔水发酵生产饲料蛋白的方法（ZL2009101447854.9，2012年授权）
  16. 一种护齿软糖及其制备方法（ZL201010281801.1，2012年授权）
  17. 一种大豆蜂蜜酸奶及其制备方法（ZL20110323632.8，2012年授权）
  18. 一种老鹰茶酸奶及其制备方法和用途（ZL201110009848.7，2012年授权）
  19. 山核桃黑豆酸奶及其制备方法（ZL201110127796.3，2012年授权）
  20. 一株辛格粒毛盘菌及其液态发酵制备胞内黑色素的方法（ZL201110072469，2012年授权）
  21. 一种粒毛盘菌黑色素染发剂及其制备方法（ZL201110094762.9， 2012年授权）
  22. 从老鹰茶中提取茶多酚的方法（ZL200910117149.7，2011年授权）
  23. 一种粒毛盘菌及由其液态发酵制备黑色素的方法（ZL200910145058.4，2011年授权）