基本情况

王立伟，暨南大学国际学院副院长，医学院生理学系主任，教授，博士生导师。1983年获广东医学院学士学位。1989获中山医科大学硕士学位。1994年至2005年在英国Liverpool大学和Cardiff大学学习及工作。1999年获Cardiff大学博士学位。2005年底被暨南大学作为学科带头人引进回国工作。

 

研究领域

细胞离子通道及其相关基因与细胞功能和疾病发生的关系

 

论文发表

  1. Mao J, Wang L, Fan A, Wang J, Xu B, Jacob TJC, Chen L*. Blockage of volume-activated chloride channels inhibits migration of nasopharyngeal carcinoma cells. Cell Physiol Biochem. 2007, 19: 249-258
  2. Boulkroune N, Wang L, March A, Walker N, Jacob TJ*. Repetitive olfactory exposure to the biologically significant steroid androstadienone causes a hedonic shift and gender dimorphic changes in olfactory evoked potentials. Neuropsychopharmacology. 2007, 32(8): 1822-1829
  3. Yang Y, Wang, L, Gaviria A, Yuan Z*, Berry C*. Proteolytic stability of insecticidal toxins expressed in recombinant bacilli. Appl Environ Microbiol. 2007, 73(1): 218-225
  4. Jacob TJC*, Wang L, Jaffer S, McPhee S. Changes in the odor quality of androstadienone during exposure-induced sensitization. Chem Senses. 2006, 31(1)-3-8
  5. Jacob TJC*, Wang L. A new method for measuring reaction times for odour detection at iso-intensity: Comparison between an unpleasant and pleasant odour. Physiol Behav. 2006, 87(3): 500-505
  6. Mao JW, Wang LW, Jacob T, Sun XR, Li H, Zhu LY, Li P, Zhong P, Nie SH, Chen LX*. Involvement of regulatory volume decrease in the migration of nasopharyngeal carcinoma cells. Cell Res. 2005, 15(5): 371-378
  7. Wang L, Chen L, Jacob TJC*. Evidence for peripheral plasticity in human odour response. J Physiol. 2004, 554: 236-244
  8. Wang L, Hari C, Chen L, Jacob T*. A new non-invasive method for recording the electro-olfactogram using external electrodes. Clin Neurophysiol. 2004, 115(7): 1631-1640
  9. Wang L, Chen L, Jacob T. ClC-3 expression in the cell cycle of nasopharyngeal carcinoma cells. Acta Physiologica Sinica. 2004, 56(2): 230-236
  10. Mao JW, Wang LW, Sun XR, Zhu LY, Li P, Zhong P, Nie SH, Jacob T, Chen LX*. Volume-activated Cl- current in migrated nasopharyngeal carcinoma cells. Acta Physiologica Sinica. 2004, 56(4): 525-530
  11. He QF, Wang LW, Mao JW, Sun XR, Li P, Zhong P, Nie SH, Jacob T, Chen LX*. Activation of chloride current and decrease of cell volume by ATP in nasopharyngeal carcinoma cells. Acta Physiologica Sinica. 2004, 56(6): 691-696
  12. acob TJC*, Fraser C, Wang L, Walker V, O'Connor S. Psychophysical evaluation of responses to pleasant and mal-odour stimulation in human subjects; adaptation, dose response and gender differences. Int J Psychophysiol. 2003, 48: 67-80
  13. Wang L, Chen L, Zhu L, Rawle M, Nie S, Zhang J, Ping Z, Kangrong C, Jacob TJ*. Regulatory volume decrease is actively modulated during the cell cycle. J Cell Physiol. 2002
  14. Chen L, Wang L, Zhu L, Nie S, Zhang J, Zhong P, Cai B, Luo H, Jacob TJ*. Cell cycle dependent expression of volume-activated chloride currents in nasopharyngeal carcinoma cells (CNE-2Z). Am J Physiol Cell Physiol. 2002, 283: C1313-1323
  15. Wang L, Walker VE, Sardi H, Fraser C, Jacob TJ*. The correlation between physiological and psychological responses to odour stimulation in human subjects. Clin Neurophysiol. 2002, 113: 542-551
  16. Chen LX*, Wang LW, Jacob T. The role of MDR1 gene in volume-activated chloride currents in pigmented ciliary epithelial cells. Acta Physiologica Sinica. 2002, 54 (1): 1-6
  17. Wang L, Chen L, Jacob TJC*. The role of ClC-3 involume-activated chloride currents and volume regulation in bovine epithelial cells demonstrated by antisense inhibition. J Physiol. 2000, 524: 63-75
  18. Chen LX*, Wang LW. Volume-activated chloride current in pigmented ciliary epithelial cells. Acta Physiologica Sinica. 2000, 52 (5): 421-426